Tianyuan Lu

发表

Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models

C. Greenwood, J. Loredo-Osti, K. Oualkacha, 2020, PLoS genetics.

Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes

C. Greenwood, J. Richards, Madeline Gregory, 2020, Cardiovascular Diabetology.

Genetic and Epigenetic Signatures Associated with the Divergence of Aquilegia Species

Linfeng Li, Xiang Gao, Aisheng Xiong, 2022, Genes.

Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis

C. Greenwood, M. Hudson, K. Klein, 2019, BMC Medical Genomics.

Identifying Causes of Fracture Beyond Bone Mineral Density: Evidence From Human Genetics

C. Greenwood, J. Richards, V. Forgetta, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study

V. Forgetta, Sirui Zhou, J. Richards, 2022, Biological Psychiatry.

Genetic and epigenetic characteristics associated with the rapid radiation of Aquilegia species

A. Xiong, Linfeng Li, Xiang Gao, 2019, bioRxiv.

Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types

J. Mar, Tianyuan Lu, 2020, Biology of sex differences.

Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases

Kevin Y. H. Liang, C. Greenwood, P. Raina, 2023, Nature Genetics.

A sparse additive model for high-dimensional interactions with an exposure variable

Yi Yang, Tianyuan Lu, Michael S Kobor, 2018, Comput. Stat. Data Anal..

Rapid Divergence Followed by Adaptation to Contrasting Ecological Niches of Two Closely Related Columbine Species Aquilegia japonica and A. oxysepala

Bao Liu, Linfeng Li, Tianyuan Lu, 2019, Genome biology and evolution.

Reshuffling of the ancestral core-eudicot genome shaped chromatin topology and epigenetic modification in Panax

Y. van de Peer, Bao Liu, J. Wendel, 2022, Nature Communications.

Genetic determinants of polygenic prediction accuracy within a population

C. Greenwood, J. Richards, V. Forgetta, 2022, Genetics.

Capturing additional genetic risk from family history for improved polygenic risk prediction

C. Greenwood, J. Richards, V. Forgetta, 2022, Communications Biology.

Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening

C. Greenwood, J. Richards, V. Forgetta, 2020, Genetics in Medicine.

H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

Dylan M. Marchione, B. Garcia, E. Bareke, 2020, Cell reports.

Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression

C. Greenwood, J. Richards, K. Oualkacha, 2021, Genetic epidemiology.

Detecting cord blood cell type-specific epigenetic associations with gestational diabetes mellitus and early childhood growth

C. Greenwood, M. Hivert, L. Bouchard, 2021, Clinical epigenetics.

Genetic and epigenetic characteristics associated with the rapid radiation of Aquilegia species

A. Xiong, Linfeng Li, Xiang Gao, 2019, bioRxiv.

Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity

Kevin Y. H. Liang, N. Timpson, J. Richards, 2022, medRxiv.

Evolutionary Contribution of Duplicated Genes to Genome Evolution in the Ginseng Species Complex

Bao Liu, Linfeng Li, J. Zhao, 2021, Genome biology and evolution.

A Polygenic Risk Score to Predict Future Adult Short Stature Among Children

C. Greenwood, J. Perry, N. Timpson, 2021, The Journal of clinical endocrinology and metabolism.

Considering strategies for SNP selection in genetic and polygenic risk scores

Lai Jiang, Linbo Wang, J. St-Pierre, 2022, Frontiers in Genetics.

Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases.

J. Richards, V. Forgetta, Tianyuan Lu, 2022, Genetics in medicine : official journal of the American College of Medical Genetics.

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

C. Greenwood, J. Kanis, D. Bennett, 2021, Genome Medicine.

Predicting ExWAS findings from GWAS data: a shorter path to causal genes

Kevin Y. H. Liang, J. Richards, Y. Farjoun, 2023, Human Genetics.

eXclusionarY: 10 years later, where are the sex chromosomes in GWASs?

Tianyuan Lu, A. D. Paterson, Zhong Wang, 2023, American journal of human genetics.

Colocalization of expression transcripts with COVID-19 outcomes is dependent on cell-type and cell-state

J. Richards, Y. Farjoun, Sirui Zhou, 2023 .

Review of Anomaly Detection Algorithms for Data Streams

Tianyuan Lu, Xiaoyong Zhao, Lei Wang, 2023, Applied Sciences.

Development of risk prediction models for depression combining genetic and early life risk factors

Tianyuan Lu, P. Silveira, C. Greenwood, 2023, Frontiers in neuroscience.

Colocalization of expression transcripts with COVID-19 outcomes is rare across cell states, cell types and organs.

J. Richards, Y. Farjoun, Sirui Zhou, 2023, medRxiv.

Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity

Kevin Y. H. Liang, N. Timpson, J. Richards, 2023, Nature Metabolism.

COL6A3-derived endotrophin mediates the effect of obesity on coronary artery disease: an integrative proteogenomics analysis

Shidong, Kevin Y. H. Liang, N. Timpson, 2023, medRxiv.

Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study

J. Richards, N. Inagaki, G. Butler-Laporte, 2022, Frontiers in Endocrinology.

COL6A3-derived endotrophin mediates the effect of obesity on coronary artery disease: 1 an integrative proteogenomics analysis 2

Kevin Y. H. Liang, N. Timpson, C. Langenberg, 2023 .

Vitamin D and the preclinical Alzheimer cognitive composite cognition (PACC) score: a two-sample mendelian randomization study

J. Richards, Yann Ilboudo, G. Butler-Laporte, 2022, medRxiv.

Novel insights into systemic sclerosis using a sensitive computational method to analyze whole-genome bisulfite sequencing data

C. Greenwood, M. Hudson, Yixiao Zeng, 2023, Clinical Epigenetics.

eXclusionarY: Ten years later, where are the sex chromosomes in GWAS?

Tianyuan Lu, A. D. Paterson, Zhong Wang, 2023, bioRxiv.

An atlas of genetic determinants of forearm fracture

O. Mäkitie, T. Tuomi, S. Movérare-Skrtic, 2023, Nature Genetics.

HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases

Kevin Y. H. Liang, A. Metspalu, T. Esko, 2023, Communications biology.

Associations of cardiometabolic polygenic risk scores with cardiovascular disease in African Americans

Tianyuan Lu, Yaffe Kristine, Yano Yuichiro, 2023, Research square.

HLA allele-calling using whole-exome sequencing identifies 129 novel associations in 11 autoimmune diseases: a multi-ancestry analysis in the UK Biobank

Kevin Y. H. Liang, A. Metspalu, T. Esko, 2023, medRxiv.

Well-Controlled Dynamic Reserves Calculation of Abnormally High-Pressured Gas Reservoirs Developed with Edge and Bottom Aquifers

Tianyuan Lu, Youyou Cheng, Cheng-qian Tan, 2023, Processes.

Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk

Tianyuan Lu, Celia M. T. Greenwood, Sirui Zhou, 2023, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vitamin D, Cognition, and Alzheimer's Disease: Observational and Two-Sample Mendelian Randomization Studies.

G. Butler-Laporte, Tianyuan Lu, Y. Ilboudo, 2024, Journal of Alzheimer's disease : JAD.

A plasma protein-based risk score to predict hip fractures

K. Hveem, B. Åsvold, E. Coward, 2024, Nature aging.

Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures

K. Hveem, B. Åsvold, A. Langhammer, 2024, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.