D. Giguère

发表

En route to a carbohydrate-based vaccine against Burkholderia cepacia.

R. Roy, T. Shiao, R. Fauré, 2007, Organic & biomolecular chemistry.

A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates

Paul A. Johnson, D. Giguère, V. Denavit, 2018, Nature Communications.

Synthesis and screening of a small glycomimetic library for inhibitory activity on medically relevant galactoside-specific lectins in assays of increasing biorelevance

H. Gabius, R. Roy, S. André, 2010 .

A practical sulfenylation of 2,5-diketopiperazines.

Ya‐Ping Sun, K. Nicolaou, D. Giguère, 2012, Angewandte Chemie.

Synthesis of stable and selective inhibitors of human galectins-1 and -3.

Sachiko Sato, R. Roy, D. Giguère, 2008, Bioorganic & medicinal chemistry.

Carbohydrate triazoles and isoxazoles as inhibitors of galectins-1 and -3.

Sachiko Sato, R. Roy, D. Giguère, 2006, Chemical communications.

Aryl O- and S-galactosides and lactosides as specific inhibitors of human galectins-1 and -3: role of electrostatic potential at O-3.

Sachiko Sato, R. Roy, S. Sirois, 2006, Bioorganic & medicinal chemistry letters.

A glycan-based plasmonic sensor for prostate cancer diagnosis.

D. Boudreau, K. Robitaille, V. Fradet, 2021, The Analyst.

Palladium-catalyzed Ullmann-type reductive homocoupling of iodoaryl glycosides.

R. Roy, T. Shiao, D. Giguère, 2012, The Journal of organic chemistry.

Synthesis of C-terminal glycopeptides via oxime resin aminolysis.

N. Voyer, D. Giguère, T. Tremblay, 2019, Chemical communications.

Aromatic thioglycoside inhibitors against the virulence factor LecA from Pseudomonas aeruginosa.

A. Imberty, R. Roy, A. Varrot, 2013, Organic & biomolecular chemistry.

Inhibitory potential of chemical substitutions at bioinspired sites of β-D-galactopyranose on neoglycoprotein/cell surface binding of two classes of medically relevant lectins.

H. Gabius, R. Roy, B. Pucci, 2011, Bioorganic & medicinal chemistry.

Synthesis of fluorinated thiodigalactoside analogues.

D. Giguère, J. St‐Gelais, Christina Leclerc, 2021, Carbohydrate research.

Synthesis and lipophilicity of trifluorinated analogues of glucose.

D. Giguère, V. Denavit, J. St‐Gelais, 2019, The Journal of organic chemistry.

Exploring the Chemistry of Non-sticky Sugars: Synthesis of Polyfluorinated Carbohydrate Analogues of d-Allopyranose.

D. Giguère, V. Denavit, J. St‐Gelais, 2019, Chemistry.

Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimal

E. Winzeler, Ya‐Ping Sun, D. Smee, 2012, Journal of the American Chemical Society.

Diversity‐Oriented Synthesis of Diol‐Based Peptidomimetics as Potential HIV Protease Inhibitors and Antitumor Agents

P. Lagüe, D. Giguère, S. Fortin, 2018, Chembiochem : a European journal of chemical biology.

Enantioselective de novo synthesis of 4-deoxy-D-hexopyranoses via hetero-Diels-Alder cycloadditions: total synthesis of ezoaminuroic acid and neosidomycin.

R. Roy, T. Shiao, D. Giguère, 2011, The Journal of organic chemistry.

Protecting-group-free synthesis of clevudine (L-FMAU), a treatment of the hepatitis B virus.

D. Giguère, T. Tremblay, Jessica B. Alcée, 2022, Organic & biomolecular chemistry.

N-Arylimidazole synthesis by cross-cycloaddition of isocyanides using a novel catalytic system

R. Roy, D. Giguère, Marc-André Bonin, 2007 .

Synthesis of Protected 3-Deoxy-3-fluoro- and 4-Deoxy-4-fluoro-d-galactopyranosides from Levoglucosan.

D. Giguère, V. Denavit, D. Lainé, 2017, The Journal of organic chemistry.

Catalytic synthesis of novel 4-C-glycosyl coumarins using a domino Heck reaction/lactonization process

R. Roy, D. Giguère, Mathieu Neault, 2009 .

Surface polysaccharides from Acinetobacter baumannii: Structures and syntheses.

D. Giguère, 2015, Carbohydrate research.

Combining glycomimetic and multivalent strategies toward designing potent bacterial lectin inhibitors.

A. Imberty, A. Arnold, R. Roy, 2011, Chemistry.

Addressing the structural complexity of fluorinated glucose analogues: Insight into lipophilicities and solvation effects.

D. Giguère, D. Lainé, J. St‐Gelais, 2020, Chemistry.

Stereoselective Synthesis of Fluorinated Galactopyranosides as Potential Molecular Probes for Galactophilic Proteins: Assessment of Monofluorogalactoside-LecA Interactions.

A. Imberty, C. Rademacher, E. Shanina, 2019, Chemistry.

Synthetic development of sugar amino acid oligomers towards novel podophyllotoxin analogues.

D. Giguère, S. Fortin, Mathieu Gagné-Boulet, 2021, Bioorganic & medicinal chemistry.

A practical sulfenylation of 2,5-diketopiperazines.

Ya‐Ping Sun, K. Nicolaou, D. Giguère, 2012, Angewandte Chemie.

Total synthesis of epicoccin G.

Ya‐Ping Sun, K. Nicolaou, D. Sarlah, 2011, Journal of the American Chemical Society.

Efficient synthesis of a galectin inhibitor clinical candidate (TD139) using a Payne rearrangement/azidation reaction cascade.

D. Giguère, V. Denavit, J. St‐Gelais, 2020, Organic & biomolecular chemistry.

Fluorine effect in nucleophilic fluorination at C4 of 1,6-anhydro-2,3-dideoxy-2,3-difluoro-β-D-hexopyranose

Laurie Carrier, D. Giguère, V. Denavit, 2020, Beilstein journal of organic chemistry.

Protecting-Group-Free Synthesis of GB1107: An Orally Active Galectin-3 Antagonist

D. Giguère, J. St‐Gelais, 2021, Synthesis.

Annulative Dimerization of Carbohydrates: Synthesis of Complex C 2 ‐Symmetrical 1,4‐Dioxane‐Sugar Hybrids

D. Giguère, J. St‐Gelais, Gabrielle Robert-Scott, 2021 .

Synthetic Inhibitors of Galectins: Structures and Syntheses

D. Giguère, V. Denavit, D. Lainé, 2018 .

Galectin-1-Specific Inhibitors as a New Class of Compounds To Treat HIV-1 Infection

M. Tremblay, R. Roy, M. Ouellet, 2011, Antimicrobial Agents and Chemotherapy.

Domino Heck/lactonization-catalyzed synthesis of 3-C-linked mannopyranosyl coumarins.

R. Roy, D. Giguère, P. Cloutier, 2009, The Journal of organic chemistry.

Ring-Opening of Benzylated Gluconolactone to Access Useful Gluconamide Conjugates

T. Shiao, D. Giguère, V. Denavit, 2017 .

Squaramide Tethered Clindamycin, Chloroquine, and Mortiamide Hybrids: Design, Synthesis, and Antimalarial Activity.

N. Voyer, D. Giguère, D. Richard, 2023, ACS Medicinal Chemistry Letters.

Synthesis of Lincosamide Analogues via Oxime Resin Aminolysis

N. Voyer, D. Giguère, T. Tremblay, 2022, Synlett.

A first QSAR model for galectin-3 glycomimetic inhibitors based on 3D docked structures.

R. Roy, S. Sirois, D. Giguère, 2006, Medicinal chemistry.

Thiol–Yne Coupling between Propargyl 2,3,4,6-Tetra-O-acetyl-β-d-glucopyranoside and Thiol: Expedient Access to Neoglycolipids

R. Roy, D. Goyard, T. Shiao, 2015 .

Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus.

S. Bourgault, D. Archambault, D. Giguère, 2023, ACS infectious diseases.

Combining glycomimetic and multivalent strategies toward designing potent bacterial lectin inhibitors.

A. Imberty, A. Arnold, R. Roy, 2011, Chemistry.

Synthesis and Hydrolysis of Aryl Fluoroglycosides

D. Giguère, J. St‐Gelais, Christina Leclerc, 2023, Journal of Fluorine Chemistry.

E. Winzeler, Ya‐Ping Sun, D. Smee, 2012, Journal of the American Chemical Society.