W. Offen

发表

Functional and informatics analysis enables glycosyltransferase activity prediction

Benjamin G. Davis, Dianna J. Bowles, Matthew G. Davidson, 2018, Nature Chemical Biology.

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine

S. A. Nasseri, S. Withers, G. Davies, 2020, Molecules.

Gluco-1H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor

G. A. van der Marel, M. Artola, G. Davies, 2018, Journal of the American Chemical Society.

Correction: Synthesis and application of a highly branched, mechanism-based 2-deoxy-2-fluoro-oligosaccharide inhibitor of endo-xyloglucanases.

H. Brumer, G. Davies, N. Jain, 2018, Organic & biomolecular chemistry.

Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases

H. Overkleeft, G. Davies, B. Florea, 2021, Chemistry.

Competitive and Covalent Inhibitors of Human Lysosomal Retaining Exoglucosidases

M. Artola, G. Davies, J. Aerts, 2018 .

Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway.

R. Kim, G. Davies, K. Stubbs, 2014, Acta crystallographica. Section D, Biological crystallography.

Structural and functional insight into human O-GlcNAcase 3

G. Davies, C. Roth, G. R. Hemsworth, 2018 .

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

H. Overkleeft, M. Artola, J. Jiang, 2017, Chemical communications.

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.

F. Parmeggiani, G. Davies, S. Charnock, 2020, Cell chemical biology.

Three-dimensional structure of a variant `Termamyl-like' Geobacillus stearothermophilus α-amylase at 1.9 Å resolution.

T. Borchert, K. Wilson, G. Davies, 2015, Acta crystallographica. Section F, Structural biology communications.

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors

G. A. van der Marel, M. Artola, G. Davies, 2017, Journal of the American Chemical Society.

Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution.

H. Gilbert, D. Scott, J. Turkenburg, 2003, Journal of molecular biology.

Structure of Papaver somniferum O-Methyltransferase 1 Reveals Initiation of Noscapine Biosynthesis with Implications for Plant Natural Product Methylation

T. Winzer, I. Graham, G. Davies, 2019, ACS Catalysis.

Discovery of a Fungal Copper Radical Oxidase with High Catalytic Efficiency toward 5-Hydroxymethylfurfural and Benzyl Alcohols for Bioprocessing

B. Henrissat, H. Brumer, E. Blagova, 2020, ACS Catalysis.

Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.

Claire Dumon, A. Vasella, L. Tailford, 2008, Nature chemical biology.

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

G. A. van der Marel, M. Artola, G. Davies, 2017, ACS central science.

In vitro and in vivo characterization of three Cellvibrio japonicus glycoside hydrolase family 5 members reveals potent xyloglucan backbone-cleaving functions

H. Brumer, G. Davies, N. Jain, 2018, Biotechnology for Biofuels.

Structural and functional insight into human O-GlcNAcase

G. Davies, C. Roth, G. R. Hemsworth, 2017, Nature chemical biology.

Structure and Activity of Paenibacillus polymyxa Xyloglucanase from Glycoside Hydrolase Family 44

H. Brumer, K. Wilson, G. Davies, 2011, The Journal of Biological Chemistry.

Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis.

S. Withers, H. Gilbert, G. Davies, 2009, Chemical communications.

Structure and activity of the Streptomyces coelicolor A3(2) β-N-acetylhexosaminidase provides further insight into GH20 family catalysis and inhibition.

N. Doucet, G. Davies, F. Shareck, 2014, Biochemistry.

An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex.

I. Smith, A. Wilkinson, R. Lewis, 1998, Journal of molecular biology.

Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A.

P. Youngman, A. Wilkinson, R. Lewis, 1999, Acta crystallographica. Section D, Biological crystallography.

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

C. Ford, G. Davies, B. G. Davis, 2006 .

Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic metabolism in plants

G. Davies, R. Edwards, D. Bowles, 2007, Proceedings of the National Academy of Sciences.

RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations.

A. Antson, A. Wilkinson, G. Dodson, 1997, Protein engineering.

Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-d-glucosidases

K. Wilson, S. McNicholas, J. Turkenburg, 2016, Acta crystallographica. Section D, Structural biology.

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

C. Ford, G. Davies, B. G. Davis, 2006, The EMBO journal.

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

H. Overkleeft, M. Artola, J. Jiang, 2017, Chemical communications.

Structural and functional insight into human O-GlcNAcase

G. Davies, C. Roth, G. R. Hemsworth, 2017, Nature chemical biology.

A Multiplexing Activity-Based Protein-Profiling Platform for Dissection of a Native Bacterial Xyloglucan-Degrading System

H. Overkleeft, W. Offen, J. Codée, 2023, ACS central science.