B. Wen

发表

Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling

Chester L. Bowen, O. Naderer, Liangfu Chen, 2014, Drug Metabolism and Disposition.

Analytical strategies for the screening and evaluation of chemically reactive drug metabolites

W. Fitch, B. Wen, 2009 .

Bioactivation of herbal constituents: mechanisms and toxicological relevance

P. Gorycki, B. Wen, 2019, Drug metabolism reviews.

A Targeted Metabolomics MRM-MS Study on Identifying Potential Hypertension Biomarkers in Human Plasma and Evaluating Acupuncture Effects

F. Liang, Hui Zheng, Shufang Deng, 2016, Scientific Reports.

Rapid screening of glutathione-trapped reactive metabolites by linear ion trap mass spectrometry with isotope pattern-dependent scanning and postacquisition data mining.

Mingshe Zhu, Q. Ruan, Li Ma, 2008, Chemical research in toxicology.

Use of Triple Quadrupole–Linear Ion Trap Mass Spectrometry as a Single LC–MS Platform in Drug Metabolism and Pharmacokinetics Studies

Mingshe Zhu, Wenying Jian, M. Yao, 2011 .

Chapter 3 Applications of Quadrupole-Linear Ion Trap Mass Spectrometry to the Analysis of Reactive Metabolites in Drug Discovery and Development

Mingshe Zhu, B. Wen, M. Zhu, 2009 .

Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry.

W. Fitch, B. Wen, 2009, Journal of mass spectrometry : JMS.

High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry.

Mingshe Zhu, S. Nelson, Li Ma, 2008, Analytical chemistry.

Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro

A. D. Rodrigues, Hongjiang Zhang, B. Wen, 2008, Drug Metabolism and Disposition.

Andrographolide Sulfonate Is a Promising Treatment to Combat Methicillin-resistant Staphylococcus aureus and Its Biofilms

T. Mahmood, Cheng Lu, N. Xie, 2021, Frontiers in Pharmacology.

Mitigation of reactive metabolite formation for a series of 3-amino-2-pyridone inhibitors of Bruton's tyrosine kinase (BTK).

P. Wovkulich, P. Di Lello, D. Fry, 2017, Bioorganic & medicinal chemistry letters.

Metabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4

Yuan Chen, W. Fitch, B. Wen, 2009, Drug Metabolism and Disposition.

Contribution of Metabolites to P450 Inhibition–Based Drug–Drug Interactions: Scholarship from the Drug Metabolism Leadership Group of the Innovation and Quality Consortium Metabolite Group

W. Humphreys, R. Walsky, C. Prakash, 2015, Drug Metabolism and Disposition.

Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s.

B. Wen, Bo Wen, Mingyan Zhou, 2009, Chemico-biological interactions.

Applications of mass spectrometry in drug metabolism: 50 years of progress*

Mingshe Zhu, B. Wen, M. Zhu, 2015, Drug metabolism reviews.

metaX: a flexible and comprehensive software for processing metabolomics data

Siqi Liu, Zhanlong Mei, B. Wen, 2017, BMC Bioinformatics.

Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase.

M. Monshouwer, W. Fitch, S. Nelson, 2008, Chemical research in toxicology.

Contribution of Metabolites to P 450 Inhibition – Based Drug – Drug Interactions : Scholarship from the Drug Metabolism Leadership Group of the Innovation and Quality Consortium Metabolite Group s

W. Humphreys, R. Walsky, C. Prakash, 2015 .

Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4

V. Roongta, Liling Liu, B. Wen, 2014, Drug Metabolism and Disposition.

Metabonomics in Understanding Drug Metabolism and Toxicology

B. Wen, 2012 .

Lipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis

Wu Zhu, Guixue Hou, Zhanlong Mei, 2017, GigaScience.

Mass Spectrometry in Drug Metabolism: Principles and Common Practice

B. Wen, 2017 .

Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s.

Li Ma, B. Wen, M. Zhu, 2008, Chemico-biological interactions.

Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH Conjugates

B. Wen, D. Moore, 2011, Drug Metabolism and Disposition.

Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and Glutathione Conjugates

B. Wen, David J. Moore, 2011 .

Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m-Chlorophenylpiperazine

A. D. Rodrigues, Li Ma, B. Wen, 2008, Drug Metabolism and Disposition.

Common Biotransformation Reactions

S. Nelson, B. Wen, 2011 .

Metabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4

Yuan Chen, W. Fitch, B. Wen, 2009, Drug Metabolism and Disposition.

Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro

Hongjiang Zhang, B. Wen, Shu-Ying Chang, 2008, Drug Metabolism and Disposition.

metaX: a flexible and comprehensive software for processing metabolomics data

Bo Wen, Siqi Liu, Zhanlong Mei, 2017, BMC Bioinformatics.

DMD057414 1044..1054

V. Roongta, Liling Liu, B. Wen, 2014 .