R. Young

发表

Genetic Toxicology Studies

M. Aardema, T. Lawlor, R. Young, 2014 .

Genetic toxicology: web resources.

Robert R Young, R. Young, 2002, Toxicology.

Interlaboratory comparison: liver spontaneous mutant frequency from lambda/lacI transgenic mice (Big Blue) (II).

J. Short, R. Young, G. S. Provost, 1995, Mutation research.

Chapter 33 – Genetic Toxicology

R. Young, 2009 .

Assessment of the mutagenic potential of para‐chloroaniline and aniline in the liver, spleen, and bone marrow of Big Blue® rats with micronuclei analysis in peripheral blood

C. Koenig, R. Young, C. Beevers, 2018, Environmental and molecular mutagenesis.

Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing

M. Fielden, Sheroy Minocherhomji, J. Salk, 2020, Proceedings of the National Academy of Sciences.

A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats

C. Thompson, D. Proctor, M. Suh, 2015, Environmental and molecular mutagenesis.

An evaluation of 25 selected ToxCast chemicals in medium‐throughput assays to detect genotoxicity

K. Houck, M. Aardema, T. Lawlor, 2015, Environmental and molecular mutagenesis.

Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats

C. Thompson, D. Proctor, M. Suh, 2017, Toxicology and applied pharmacology.

Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488.

M. Aardema, Andrew Williams, C. Yauk, 2018, Mutation research. Genetic toxicology and environmental mutagenesis.

Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats

C. Thompson, D. Proctor, M. Suh, 2015, Environmental and molecular mutagenesis.

A review of mammalian in vivo genotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment

J. T. Macgregor, M. Aardema, C. Thompson, 2021, Critical reviews in toxicology.

Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing.

M. Aardema, Andrew Williams, C. Yauk, 2018, Mutation research. Genetic toxicology and environmental mutagenesis.

Tissue‐specific mutant frequencies and mutational spectra in cyclophosphamide‐treated lacI transgenic mice

V. Walker, R. Young, N. Gorelick, 1999, Environmental and molecular mutagenesis.

Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review

C. Yauk, F. Marchetti, J. van Benthem, 2022, Environmental and molecular mutagenesis.

Selection and Evaluation of an Appropriate Model for Screening Adenosine Analogs for Chromosome Aberrations

S. Gad, R. Young, P. Guzzie, 1991 .

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

M. LeBaron, K. Witt, M. Aardema, 2019, Mutation research. Genetic toxicology and environmental mutagenesis.

28‐Day somatic gene mutation study of 1‐bromopropane in female Big Blue® B6C3F1 mice via whole‐body inhalation: Support for a carcinogenic threshold

R. Young, J. Weinberg, M. Stelljes, 2019, Regulatory toxicology and pharmacology : RTP.

In vitro and in vivo assays of isopropanol for mutagenicity

R. Kapp, R. H. Mckee, D. J. Marino, 1993, Environmental and molecular mutagenesis.

Intralaboratory optimization and standardization of mutant screening conditions used for a lambda/lacI transgenic mouse mutagenesis assay (I).

J. Short, R. Young, G. S. Provost, 1995, Mutation research.

Evaluation of spontaneous and chemical-induced lacI mutations in germ cells from lambda/lacI transgenic mice.

G. Carr, R. Young, D. Putman, 1997, Mutation research.

Lack of genotoxic effects of sucrose acetate isobutyrate (SAIB).

T. Lawlor, M. Cifone, R. Young, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Assessment of the genotoxicity of calcium cyclamate and cyclohexylamine

D. Brusick, M. Cifone, R. Young, 1989, Environmental and molecular mutagenesis.

Assessment of the potential genotoxicity of perfluorodecanoic acid and chlorotrifluoroethylene trimer and tetramer acids.

T. Lawlor, C. Godin, B C Myhr, 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Summary of in vitro genetic toxicology assay results: Expected and unexpected effects of recent study design modifications

V. O. Wagner, M. Aardema, T. Lawlor, 2012, Environmental and molecular mutagenesis.

Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

K. Witt, C. Yauk, F. Marchetti, 2023, Nature Reviews Drug Discovery.

Error-corrected Next Generation Sequencing - Promises and Challenges for Genotoxicity and Cancer Risk Assessment.

K. Witt, F. Marchetti, Sheroy Minocherhomji, 2023, Mutation research. Reviews in mutation research.

Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): How genomics is on the path to modernizing Genetic Toxicology.

I. Martincorena, K. Witt, J. Kucab, 2023, Mutagenesis.

Tissue‐specific mutant frequencies and mutational spectra in cyclophosphamide‐treated lacI transgenic mice

V. Walker, R. Young, N. Gorelick, 1999, Environmental and molecular mutagenesis.

Genotoxicity Assessment of Mixed Oligomers of Chlorotrifluoroethylene using a Battery of In Vitro and In Vivo/In Vitro Assays

T. Lawlor, R. Young, B. Myhr, 1990 .

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

M. LeBaron, K. Witt, M. Aardema, 2019, Mutation research. Genetic toxicology and environmental mutagenesis.