D. Torous

发表

Evaluation of the rodent micronucleus assay by a 28‐day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)–Mammalian Mutagenicity Study Group (MMS)

A. Wakata, M. Hayashi, T. Morita, 2001, Environmental and molecular mutagenesis.

Comparison of male versus female responses in the Pig-a mutation assay.

J. T. Macgregor, J. Bemis, S. Dertinger, 2015, Mutagenesis.

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Dushan N. Wadduwage, L. Samson, F. White, 2021, bioRxiv.

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Dushan N. Wadduwage, L. Samson, F. White, 2020, bioRxiv.

Flow cytometric analysis of Pig‐a gene mutation and chromosomal damage induced by procarbazine hydrochloride in CD‐1 mice

J. T. Macgregor, J. Bemis, S. Dertinger, 2013, Environmental and molecular mutagenesis.

Persistence of cisplatin-induced mutagenicity in hematopoietic stem cells: implications for secondary cancer risk following chemotherapy.

J. T. Macgregor, J. Bemis, S. Dertinger, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Diet‐induced obesity increases the frequency of Pig‐a mutant erythrocytes in male C57BL/6J mice

S. Dertinger, D. Torous, Mark Wilson, 2016, Environmental and molecular mutagenesis.

Part 2. Assessment of micronucleus formation in rats after chronic exposure to new-technology diesel exhaust in the ACES bioassay.

J. Bemis, S. Dertinger, D. Torous, 2015, Research report.

Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.

J. Bemis, S. Dertinger, W. Slob, 2016, Mutagenesis.

Micronucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans.

Yuhchyau Chen, S. Dertinger, D. Torous, 2003, Mutation research.

Part 2. Assessment of genotoxicity after exposure to diesel exhaust from U.S. 2007-compliant diesel engines: report on 1- and 3-month exposures in the ACES bioassay.

J. Bemis, S. Dertinger, D. Torous, 2012, Research report.

Flow cytometric analysis of micronuclei in peripheral blood reticulocytes: I. Intra- and interlaboratory comparison with microscopic scoring.

J. T. Macgregor, Takayoshi Suzuki, M. Moore, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Interlaboratory validation of a CD71‐based flow cytometric method (Microflow®) for the scoring of micronucleated reticulocytes in mouse peripheral blood

P. Harbach, K. Sandelin, L. Ferguson, 2005, Environmental and molecular mutagenesis.

Three‐color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood

K. Camphausen, C. Ménard, J. T. Macgregor, 2004, Environmental and molecular mutagenesis.

Flow cytometric enumeration of micronucleated reticulocytes: High transferability among 14 laboratories

M. Fenech, P. Harbach, K. Sandelin, 2001, Environmental and molecular mutagenesis.

In vivo flow cytometric Pig‐a and micronucleus assays: Highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated‐dose designs

J. T. Macgregor, J. Bemis, S. Dertinger, 2012, Environmental and molecular mutagenesis.

Assessment of systemic genetic damage in pediatric inflammatory bowel disease

J. T. Macgregor, J. Bemis, S. Dertinger, 2020, Environmental and molecular mutagenesis.

Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate.

J. T. Macgregor, J. Bemis, S. Dertinger, 2015, Mutagenesis.

3Rs friendly study designs facilitate rat liver and blood micronucleus assays and Pig‐a gene mutation assessments: Proof‐of‐concept with 13 reference chemicals

J. T. Macgregor, J. Bemis, S. Dertinger, 2019, Environmental and molecular mutagenesis.

Mouse Pig‐a and micronucleus assays respond to N‐ethyl‐N‐nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate

J. T. Macgregor, J. Bemis, S. Dertinger, 2016, Environmental and molecular mutagenesis.

Pig‐a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3‐propane sultone

J. T. Macgregor, J. Bemis, S. Dertinger, 2014, Environmental and molecular mutagenesis.

Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.

J. T. Macgregor, J. Bemis, S. Dertinger, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals.

Raymond R Tice, Leslie Recio, Kristine L Witt, 2008, Mutation research.

Cross‐Species Genetic Toxicity Assessment Accomplished by Flow Cytometric Analysis of Blood

J. Bemis, S. Dertinger, D. Torous, 2008, Current protocols in toxicology.

Flow cytometry assay for counting micronucleated erythrocytes: development process.

J. Weaver, D. Torous, 2000, Methods.

Flow cytometric scoring of micronucleated erythrocytes: an efficient platform for assessing in vivo cytogenetic damage.

Stephen D Dertinger, Makoto Hayashi, J. T. Macgregor, 2011, Mutagenesis.

Practical threshold for micronucleated reticulocyte induction observed for low doses of mitomycin C, Ara-C and colchicine.

S. Dertinger, M. Hayashi, T. Morita, 2006, Mutagenesis.

Performance of flow cytometric analysis for the micronucleus assay--a reconstruction model using serial dilutions of malaria-infected cells with normal mouse peripheral blood.

S. Dertinger, M. Hayashi, T. Morita, 2006, Mutagenesis.

Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage.

Yuhchyau Chen, S. Dertinger, Steven M. Bryce, 2007, Mutation research.

Enumeration of micronucleated reticulocytes in rat peripheral blood: a flow cytometric study.

S. Dertinger, D. Torous, D K Torous, 2000, Mutation research.

Malaria-infected erythrocytes serve as biological standards to ensure reliable and consistent scoring of micronucleated erythrocytes by flow cytometry.

S. Dertinger, T. Gasiewicz, D. Torous, 2000, Mutation research.

Lack of DNA Polymerase θ (POLQ) Radiosensitizes Bone Marrow Stromal Cells In Vitro and Increases Reticulocyte Micronuclei after Total-Body Irradiation

Hong Wang, R. Wood, S. Dertinger, 2009, Radiation research.

Enumeration of micronucleated CD71-positive human reticulocytes with a single-laser flow cytometer.

S. Dertinger, D. Torous, Richard K. Miller, 2002, Mutation research.

Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry.

O. Hyrien, Yuhchyau Chen, J. Bemis, 2007, Mutation research.

Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens.

Ollivier Hyrien, Stephen D Dertinger, James Palis, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Inter-laboratory validation of the in-vivo flow cytometric micronucleus analysis method (MicroFlow®) in China.

S. Dertinger, Zhaomin Zhong, Yang Luan, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies.

J. T. Macgregor, O. Hyrien, J. Bemis, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy.

Stephen D Dertinger, S. Dertinger, D. Torous, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Simultaneous Measurement of Benzo[a]pyrene-induced Pig-a and lacZ Mutations, Micronuclei and DNA Adducts in Muta™ Mouse

P. White, V. Arlt, D. Phillips, 2011, Environmental and molecular mutagenesis.

Integration of liver and blood micronucleus and Pig-a gene mutation endpoints into rat 28-day repeat-treatment studies: Proof-of-principle with diethylnitrosamine.

J. Bemis, S. Dertinger, D. Torous, 2018, Mutation research. Genetic toxicology and environmental mutagenesis.

Flow cytometric method for scoring rat liver micronuclei with simultaneous assessments of hepatocyte proliferation

J. Bemis, S. Dertinger, D. Torous, 2018, Environmental and molecular mutagenesis.

Diethylnitrosamine genotoxicity evaluated in sprague dawley rats using Pig‐a mutation and reticulocyte micronucleus assays

J. T. Macgregor, J. Bemis, S. Dertinger, 2014, Environmental and molecular mutagenesis.

Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays.

J. Bemis, S. Dertinger, L. Saubermann, 2020, Mutagenesis.

In vivo pig‐a and micronucleus study of the prototypical aneugen vinblastine sulfate

J. T. Macgregor, J. Bemis, S. Dertinger, 2018, Environmental and molecular mutagenesis.

Interlaboratory Pig‐a gene mutation assay trial: Studies of 1,3‐propane sultone with immunomagnetic enrichment of mutant erythrocytes

J. T. Macgregor, J. Bemis, S. Dertinger, 2011, Environmental and molecular mutagenesis.

Assessment of 5‐fluorouracil and 4‐nitroquinoline‐1‐oxide in vivo genotoxicity with Pig‐a mutation and micronucleus endpoints

S. Dertinger, D. Torous, Honggang Tu, 2014, Environmental and molecular mutagenesis.

Suitability of Long‐Term Frozen Rat Blood Samples for the Interrogation of Pig‐a Gene Mutation by Flow Cytometry

J. Bemis, S. Dertinger, J. Bhalli, 2018, Environmental and molecular mutagenesis.

A cross‐sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements

K. Shockley, K. Witt, J. Bemis, 2022, Environmental and molecular mutagenesis.

In vitro system for detecting nongenotoxic carcinogens

S. Dertinger, D. Torous, A. Tometsko, 1993, Environmental and molecular mutagenesis.

An automated method for discriminating aneugen‐ vs. clastogen‐induced micronuclei

S. Dertinger, D. Torous, D K Torous, 1998, Environmental and molecular mutagenesis.

Flow cytometric analysis of micronuclei in rat peripheral blood: An interlaboratory reproducibility study.

M. Hayashi, J. Yamate, D. Torous, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

P-118 / O-14 Cyclophosphamide and Etoposide Canine Studies Demonstrate the Cross-Species Potential of the Peripheral Blood Micronucleated Reticulocyte Endpoint(Poster Session)

S. Dertinger, D. Kirkland, G. Schmuck, 2008 .

Influence of counting methodology on erythrocyte ratios in the mouse micronucleus test

M. LeBaron, S. Dertinger, B. Gollapudi, 2013, Environmental and molecular mutagenesis.

Human blood PIG‐A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra‐ and inter‐subject variation

J. T. Macgregor, Yuhchyau Chen, J. Bemis, 2020, Environmental and molecular mutagenesis.

Induction and time-dependent accumulation of micronuclei in peripheral blood of transgenic p53+/- mice, Tg.AC (v-Ha-ras) and parental wild-type (C57BL/6 and FVB/N) mice exposed to benzene by inhalation.

J. French, L. Pluta, L. Recio, 2001, Mutagenesis.

Flow cytometric analysis of Pig‐a gene mutation and chromosomal damage induced by procarbazine hydrochloride in CD‐1 mice

J. T. Macgregor, J. Bemis, S. Dertinger, 2013, Environmental and molecular mutagenesis.

Simple and reliable enumeration of micronucleated reticulocytes with a single-laser flow cytometer.

S. Dertinger, D. Torous, D. Torous, 1996, Mutation research.

Intra‐ and inter‐laboratory reproducibility of the rat blood Pig‐a gene mutation assay

A. Elhajouji, J. Bemis, S. Dertinger, 2020, Environmental and molecular mutagenesis.

Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.

J. Bemis, S. Dertinger, W. Slob, 2016, Mutagenesis.

Impact of p53 status on heavy-ion radiation-induced micronuclei in circulating erythrocytes.

P. Chang, L. Lutze-Mann, D. Torous, 2000, Mutation research.