A. Erxleben

发表

Application of Vibrational Spectroscopy to Study Solid-state Transformations of Pharmaceuticals.

A. Erxleben, 2016, Current pharmaceutical design.

Effects of ball-milling and cryomilling on sulfamerazine polymorphs: a quantitative study.

Pól Macfhionnghaile, P. McArdle, Yun Hu, 2014, Journal of pharmaceutical sciences.

Accessing New 5‐α‐(3,3‐Disubstituted Oxindole)‐Benzylamine Derivatives from Isatin: Stereoselective Organocatalytic Three Component Petasis Reaction

C. S. Marques, A. Burke, P. McArdle, 2020, European Journal of Organic Chemistry.

Supramolecular Structures and Tautomerism of Carboxylate Salts of Adenine and Pharmaceutically Relevant N6-Substituted Adenine

A. Erxleben, C. McHugh, 2011 .

Structures and properties of Zn(II) coordination polymers

A. Erxleben, 2003 .

Effects of material thickness and processing method on poly(lactic-co-glycolic acid) degradation and mechanical performance

Reyhaneh Neghabat Shirazi, P. McHugh, Y. Rochev, 2016, Journal of Materials Science: Materials in Medicine.

A Comprehensive Cocrystal Screening Study of Chlorothiazide

A. Pallipurath, P. McArdle, A. Erxleben, 2017 .

Rapid hydrolysis of phosphate monoesters by zirconium(IV) complexes in neutral solution

A. Erxleben, F. Coleman, 2012 .

Di- and poly-nuclear zinc(II) Schiff base complexes: synthesis, structural studies and reaction with an α-amino acid ester

A. Erxleben, J. Hermann, 2000 .

Sublimation – a green route to new solid-state forms

P. McArdle, A. Erxleben, 2021, CrystEngComm.

A Comprehensive near Infrared Spectroscopic Study of the Limits of Quantitative Analysis of Sulfathiazole Polymorphism

Pól Macfhionnghaile, P. McArdle, Yun Hu, 2013 .

Cytotoxicity and ROS production of novel Pt(IV) oxaliplatin derivatives with indole propionic acid

M. Devereux, A. Erxleben, Dina A. Tolan, 2019, Inorganica Chimica Acta.

DNA damage and induction of apoptosis in pancreatic cancer cells by a new dinuclear bis(triazacyclonane) copper complex.

V. Gandin, C. Marzano, A. Erxleben, 2015, Journal of inorganic biochemistry.

Mixed ligand cobalt(II) picolinate complexes: synthesis, characterization, DNA binding and photocleavage.

C. Näther, A. Erxleben, A. Kumbhar, 2011, Dalton transactions.

Cytotoxicity and antimicrobial activity of triorganotin(IV) complexes of phenylcyanamide prepared by sonochemical synthesis

P. McArdle, A. Erxleben, L. Tabrizi, 2015 .

Application vibrational spectroscopy to study solid-state transformations of

A. Erxleben, 2019 .

Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling.

V. Caron, A. Healy, O. Corrigan, 2013, Molecular pharmaceutics.

Crystalline adducts of the Lawsone molecule (2-hydroxy-1,4-naphthaquinone): optical properties and computational modelling

J. Skelton, W. Jones, A. Pallipurath, 2015 .

Salts, Binary and Ternary Cocrystals of Pyrimethamine: Mechanosynthesis, Solution Crystallization, and Crystallization from the Gas Phase

P. McArdle, A. Erxleben, Niamh Walsh, 2021 .

Interactions between [AuX4]− (X = Cl, CN) and cytosine and guanine model nucleobases: salt formation with (hemi-) protonated bases, coordination, and oxidative degradation of guanine

E. Freisinger, A. Schimanski, B. Lippert, 1998 .

Synthesis and spectroscopy of phosphonate derivatives of uracil and thymine. X‐ray crystal structure of diethyl 6‐uracilmethylphosphonate

B. Lippert, J. Ochocki, A. Erxleben, 1997 .

Antitumor platinum(IV) derivatives of carboplatin and the histone deacetylase inhibitor 4-phenylbutyric acid.

L. Morrison, V. Gandin, C. Marzano, 2017, Journal of inorganic biochemistry.

Oxidative Stress Induced by Pt(IV) Pro-drugs Based on the Cisplatin Scaffold and Indole Carboxylic Acids in Axial Position

L. Morrison, V. Gandin, C. Marzano, 2016, Scientific Reports.

phosphate-targeted dinuclear Cu(II) complex combining groove binding and oxidative DNA

C. Slator, Z. Molphy, A. Kellett, 2020 .

Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes

V. Gandin, A. Kellett, C. Marzano, 2019, JBIC Journal of Biological Inorganic Chemistry.

Synthesis, single-crystal and solution structure analysis and in vitro cytotoxic activity of two novel complexes of ruthenium(II) with in situ formed flavanone-based ligands.

L. Szmigiero, A. Garza-Ortiz, J. Reedijk, 2010, Dalton transactions.

Spontaneous reduction of mixed 2,2'-bipyridine/methylamine/chloro complexes of Pt(IV) in water in the presence of light is accompanied by complex isomerization, loss of methylamine, and formation of a strong oxidant, presumably HOCl.

B. Meunier, G. Pratviel, B. Lippert, 2007, Chemistry.

Solid-state transformations of sulfathiazole polymorphs: The effects of and

Alan G. Ryder, Boyan Li, P. McArdle, 2020 .

Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug.

V. Caron, A. Healy, Pól Macfhionnghaile, 2013, Journal of pharmaceutical sciences.

Synthesis and structure of [[Ag(SalGly)].0.33H20]n: an infinite double helical coordination polymer.

A. Erxleben, 2001, Inorganic chemistry.

Hydrogen bond directed honeycomb-like porous network structure of tris(bipyridyl-glycoluril)cobalt(III) chloride

R. Banerjee, Pradip Pachfule, A. Erxleben, 2011 .

Transition metal salen complexes in bioinorganic and medicinal chemistry

A. Erxleben, 2017 .

Coordination polymers derived from silver salts and an aliphatic N , O ligand

A. Erxleben, 2003 .

Synthesis, spectroscopy and magnetism of novel metal complexes of 3-aminoflavone (3-af). X-ray crystal structure of 3-af and [Cu(3-af)2(NO3)2]

J. Ochocki, A. Erxleben, B. Żurowska, 2009 .

Synthesis, crystal structure and solution behavior of a novel tetranuclear Zn(II) Schiff base complex

A. Erxleben, J. Hermann, 2000 .

Phosphate Diester Cleavage, DNA Interaction and Cytotoxic Activity of a Bimetallic Bis(1,4,7‐triazacyclononane) Zinc Complex

V. Gandin, C. Marzano, A. Erxleben, 2014 .

A comprehensive spectroscopic study of the polymorphs of and their phase

J. A. Zeitler, J. Sibik, A. Pallipurath, 2019 .

A comprehensive spectroscopic study of the polymorphs of diflunisal and their phase transformations.

J. A. Zeitler, J. Sibik, A. Pallipurath, 2017, International journal of pharmaceutics.

Unexpected effects of catalytic amounts of additives on crystallization from the gas phase: Depression of the sublimation temperature and polymorph control

P. McArdle, A. Erxleben, N. Kamali, 2016 .

Formation of Salts and Molecular Ionic Cocrystals of Fluoroquinolones and α,ω-Dicarboxylic Acids

A. Erxleben, Ciarán O’Malley, P. McArdle, 2022, Crystal growth & design.

Dual-drug amorphous formulation of gliclazide

P. McArdle, A. Erxleben, Marwah Aljohani, 2021, Drug development and industrial pharmacy.

Influence of Excipients on Cocrystal Stability and Formation

P. McArdle, A. Erxleben, Marwah Aljohani, 2020, Crystal Growth & Design.

Heteronuclear μ-1-methylcytosinato-N3,N4 complexes containing very short Pt → Cu dative bonds

B. Lippert, A. Erxleben, J. Hüttermann, 1996 .

The Uracil C(5) Position as a Metal Binding Site: Solution and X-ray Crystal Structure Studies of Pt(II) and Hg(II) Compounds.

B. Lippert, A. Erxleben, Ingo Rombeck, 1996, Inorganic chemistry.

Nickel(II) and cobalt(II) complexes of lidocaine: Synthesis, structure and comparative in vitro evaluations of biological perspectives.

P. McArdle, A. Erxleben, L. Tabrizi, 2015, European journal of medicinal chemistry.

Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)2(X)2] X2 · nH2O (X=NO3−,CIO4−) and [Cu(L′)]2 · 2CH3OH

A. Erxleben, 2009 .

Magnesium Versus Zinc Coordination to Multidentate Schiff Base Ligands

A. Erxleben, D. Schumacher, 2001 .

Solvent‐dependent Switch of Magnesium Ions between Different Binding Sites in a Compartmental Schiff Base Ligand

A. Erxleben, F. Coleman, D. Dux, 2013 .

On Mixed‐Valence Dinuclear PtII, PtIII Nucleobase Complexes Derived from cis‐Diamineplatinum(II): Effect of steric bulk of amine ligands on the Pt‐oxidation state

B. Lippert, A. Erxleben, Matthias Peilert, 1996 .

Anion‐Dependent Substitution of Zinc by Magnesium in Mononuclear Schiff Base Complexes

A. Erxleben, J. Hermann, D. Schumacher, 2002 .

Mono- and dinuclear zinc complexes derived from unsymmetric binucleating ligands: synthesis, characterization, and formation of tetranuclear arrays.

A. Erxleben, 2001, Inorganic chemistry.

DNA binding, cleavage and cytotoxicity of a novel dimetallic Fe(III) triaza-cyclononane complex

V. Gandin, P. Kavanagh, L. Nodari, 2016 .

Synthesis and spectroscopy of diethyl (pyridinylmethyl)phosphates and their palladium (II) complexes: X-ray crystal structures of Pd(II) complexes

B. Lippert, J. Ochocki, A. Erxleben, 2005 .

Model of the most abundant DNA interstrand cross-link of Transplatin: X-ray structures of two modifications and H bonding behavior in the solid state and in solution of trans-[Pt(NH3)2(1-MeC-N3)(9-EtGH-N7)](ClO4)2·nH2O (1-MeC=1-methylcytosine; 9-EtGH=9-ethylguanine)

J. Britten, A. Albinati, B. Lippert, 2002 .

Interactions of copper complexes with nucleic acids

A. Erxleben, 2018 .

A Cu(ii) complex targeting the translocator protein: in vitro and in vivo antitumor potential and mechanistic insights.

V. Gandin, A. Erxleben, B. Fresch, 2016, Chemical communications.

Advances in the Development of DNA-Cleaving Metal Complexes as Anticancer Agents

A. Erxleben, 2013 .

Interactions of molybdocene dichloride with histidine- and methionine-containing peptides

A. Erxleben, J. Kottmann, 2006 .

Ruthenium(II) polypyridyl complexes with hydrophobic ancillary ligand as Aβ aggregation inhibitors.

Vinod Jani, A. Erxleben, A. Kumbhar, 2016, European journal of medicinal chemistry.

Mechanistic Studies of Homo- and Heterodinuclear Zinc Phosphoesterase Mimics: What Has Been Learned?

A. Erxleben, 2019, Front. Chem..

Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters.

A. Erxleben, M. Tacke, J. Claffey, 2010, Journal of inorganic biochemistry.

Mitochondria-Targeting Anticancer Metal Complexes.

A. Erxleben, 2019, Current medicinal chemistry.

Application of Ball Milling for Highly Selective Mechanochemical Polymorph Transformations

P. McArdle, A. Erxleben, Katarzyna Gniado, 2018, Organic Process Research & Development.

A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage

C. Slator, Z. Molphy, A. Kellett, 2018, Nucleic acids research.

Properties and applications of flavonoid metal complexes

J. Ochocki, A. Erxleben, Maria M Kasprzak, 2015 .

trans-a2Pt(II) (a=NH3, CH3NH2) modified purine base pairs and triples: Hydrogen bonding between self-complementary pairs and triples and heterometal (Ag+) coordination leading to a 1 D helix

E. Freisinger, B. Lippert, A. Erxleben, 2000 .

Heteronuclear Pt–Pd, Pt2Cu and Pt2Ni complexes with bridging acetamidate: crystal structures and spectroscopic studies

A. Albinati, B. Lippert, A. Erxleben, 1996 .

First examples of polymeric mixed-metal (Pt–Ag) complexes containing single acetamidate bridges: cis-[(NH3)2Pt(NHCOMe)2Ag]NO3·4H2O and trans-[(NH3)2Pt(NHCOMe)2Ag]NO3·1.5H2O

B. Lippert, A. Erxleben, 1996 .

Conversion of acetonitrile into acetamide in the co-ordination spheres of cis- and trans-MII(amine)2(M = Pt or Pd). Solution and crystal structural studies

B. Lippert, A. Erxleben, I. Mutikainen, 1994 .

Expanding the NUIG MOF family: synthesis and characterization of new MOFs for selective CO2 adsorption, metal ion removal from aqueous systems, and drug delivery applications.

L. Morrison, M. Zaworotko, A. Tasiopoulos, 2021, Dalton transactions.

Silver co-ordination compounds with aliphatic nitriles containing amino nitrogen as H bond donor or additional metal binding site: formation of a ring, a chain, a polymeric sheet and a 3D polymeric channeled structure

A. Erxleben, 2002 .

Copper(ii) mixed-ligand polypyridyl complexes with doxycycline - structures and biological evaluation.

F. Hoffmann, J. Obaleye, Ayesha Khan, 2016, Dalton transactions.

Title Application of ball milling for highly selectivemechanochemical polymorph transformations

P. McArdle, A. Erxleben, Katarzyna Gniado, 2019 .

Reaction behavior of molybdocene dichloride towards ribonucleosides and ribonucleoside monophosphates: Rare example of sugar coordination

A. Erxleben, Lyuba Yovkova, 2006 .

Platinum complex [(en)Pt(uracilate)]44+: a metal analog of calix[4]arene. Similarities and differences with classical calix[4]arenes

B. Lippert, A. Erxleben, H. Rauter, 1994 .

Synthesis and structure of a helical coordination polymer: ([Zn2(bdaip)(mu-OH)(OH)]NO3.2H2O) infinity (Hbdaip. = 2,6-bis(N-[2-(dimethylamino)ethyl]iminomethyl)-4-methylphenol).

A. Erxleben, 2001, Inorganic chemistry.

Ga(III) complexes as models for the M(III) site of purple acid phosphatase: ligand effects on the hydrolytic reactivity toward bis(2,4-dinitrophenyl) phosphate.

Andrea Erxleben, M. Hynes, Michael J Hynes, 2010, Inorganic chemistry.

The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems.

Pól Macfhionnghaile, P. McArdle, A. Erxleben, 2018, International journal of pharmaceutics.

Solid-state transformations of sulfathiazole polymorphs: The effects of milling and humidity

Alan G. Ryder, B. K. Hodnett, Å. Rasmuson, 2013 .

Amorphous Solid Dispersions of Sulfonamide/Soluplus® and Sulfonamide/PVP Prepared by Ball Milling

A. Healy, O. Corrigan, P. McArdle, 2013, AAPS PharmSciTech.

Heteronuclear Nucleobase Complexes as Tools for the Isolation of the Minor Rotamer of the Parent Compound: Synthesis and Crystal Structure Determination of Head-Head and Head-Tail Forms of trans-[(CH3NH2)2Pt(1-MeC-N3)2]2+ (1-MeC = 1-methylcytosine)

I. Sóvágó, B. Lippert, A. Erxleben, 1995 .

Glycosyl squaramides, a new class of supramolecular gelators.

R. Moreira, A. Erxleben, S. Arufe, 2020, Soft matter.

Unprecedented morphology control of gas phase cocrystal growth using multi zone heating and tailor made additives.

P. McArdle, A. Erxleben, Ciarán O’Malley, 2020, Chemical communications.

Ternary complex of cisplatin with glycine and 1-methyluracil: cis-[(NH3)2Pt(glyH-N)(1-MeU-N3)]ClO4·H2O

B. Lippert, A. Erxleben, S. Höhmann, 1996 .

Differences in Coformer Interactions of the 2,4-Diaminopyrimidines Pyrimethamine and Trimethoprim

J. Simmie, P. McArdle, A. Erxleben, 2022, Crystal growth & design.

Hydrogen Bonding Networks and Solid-State Conversions in Benzamidinium Salts

P. McArdle, A. Erxleben, N. Kamali, 2015 .

Cocrystal Applications in Drug Delivery

A. Erxleben, 2020, Pharmaceutics.

Anisotropic Crystal Growth in Flat and Nonflat Systems: The Important Influence of van der Waals Contact Molecular Stacking on Crystal Growth and Dissolution

N. Walshe, J. Karpinska, P. McArdle, 2015 .

Tailoring Cocrystal and Salt Formation and Controlling the Crystal Habit of Diflunisal

A. Pallipurath, P. McArdle, A. Erxleben, 2016 .

Synthesis, Crystal Structure and Electrochemical Studies of a Hydrazone Schiff Base Complex of Titanium(IV)

P. Mayer, H. H. Monfared, A. Erxleben, 2009 .

Spontaneous Solid-State Cocrystallization of Caffeine and Urea

Pól Macfhionnghaile, P. McArdle, A. Erxleben, 2020, Crystal Growth & Design.

Mechanochemical Reaction of Sulfathiazole with Carboxylic Acids: Formation of a Cocrystal, a Salt, and Coamorphous Solids

Yun Hu, Andrea Erxleben, Patrick McArdle, 2014 .

The Very Different Effect of Water on Nucleation, Crystallization, and Hydrate Stability of Zingerone and Vanillate Esters

P. McArdle, A. Erxleben, Marwah Aljohani, 2020, Crystal Growth & Design.

Shining Light on Growth-Dependent Surface Chemistry of Organic Crystals: A Polarized Raman Spectroscopic and Computational Study of Aspirin

J. Skelton, A. Pallipurath, P. McArdle, 2019, Crystal Growth & Design.

17β-Hydroxy-17α-methylandrosta-1,4-dien-3-one

Jolanta Karpinska, Andrea Erxleben, Patrick McArdle, 2012, Acta crystallographica. Section E, Structure reports online.

Nanomechanical properties of poly(lactic-co-glycolic) acid film during degradation.

Reyhaneh Neghabat Shirazi, Fawaz Aldabbagh, Andrea Erxleben, 2014, Acta biomaterialia.

Novel Pt(IV) Pro-drugs Displaying Antimitochondrial Effects.

C. Chintha, L. Morrison, Afshin Samali, 2020, Molecular pharmaceutics.

Pt(IV) pro-drugs with an axial HDAC inhibitor demonstrate multimodal mechanisms involving DNA damage and apoptosis independent of cisplatin resistance in A2780/A2780cis cells.

M. Devereux, L. Morrison, A. Erxleben, 2020, Journal of inorganic biochemistry.

The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems.

T. Rades, K. Löbmann, A. Erxleben, 2016, International journal of pharmaceutics.

Investigation of the formation of drug‐drug cocrystals and coamorphous systems of the antidiabetic drug gliclazide

Pól Macfhionnghaile, P. McArdle, A. Erxleben, 2019, International journal of pharmaceutics.

Factors Controlling Persistent Needle Crystal Growth: The Importance of Dominant One-Dimensional Secondary Bonding, Stacked Structures, and van der Waals Contact

P. McArdle, A. Erxleben, Ciarán O’Malley, 2021, Crystal growth & design.

Manipulating Cocrystal Size and Morphology using a Combination of Temperature Cycling and Additives

D. Croker, V. Svoboda, P. McArdle, 2020 .

Water-based ultrasonic synthesis of SbSI nanoneedles

G. O'Connor, Y. Gun’ko, Y. Rochev, 2015 .

Gold(I) Complexes with a Quinazoline Carboxamide Alkynyl Ligand: Synthesis, Cytotoxicity, and Mechanistic Studies

C. Chintha, J. Ramos, L. Morrison, 2021, European journal of inorganic chemistry.

Co-crystal forms of the BCS class IV drug sulfamethoxazole

P. McArdle, A. Erxleben, Marwah Aljohani, 2018, Acta Crystallographica Section A Foundations and Advances.

Quantitative analysis of sulfathiazole polymorphs in ternary mixtures by attenuated total reflectance infrared, near-infrared and Raman spectroscopy.

Alan G. Ryder, P. McArdle, Yun Hu, 2010, Journal of pharmaceutical and biomedical analysis.

Crystallization from the Gas Phase: Morphology

P. McArdle, A. Erxleben, 2020 .

Effects of ball-milling and cryomilling on sulfamerazine polymorphs: A quantitative

Pól Macfhionnghaile, P. McArdle, Yun Hu, 2018 .

Applications of Low Temperature Gradient Sublimation in Vacuo: Rapid Production of High Quality Crystals. The First Solvent-Free Crystals of Ethinyl Estradiol

J. Karpinska, P. McArdle, A. Erxleben, 2013 .

17β-Hydroxy-17α-methylandrostano[3,2-c]pyrazole, Stanozolol: The Crystal Structures of Polymorphs 1 and 2 and 10 Solvates

J. Karpinska, P. McArdle, A. Erxleben, 2011 .

Investigation of Non-covalent Interactions of Metal Complexes with DNA in Cell-free Systems.

A. Erxleben, 2017, Chimia.

Amorphous Solid Dispersions of Sulfonamide/Soluplus® and Sulfonamide/PVP Prepared by Ball Milling

V. Caron, A. Healy, O. Corrigan, 2013, AAPS PharmSciTech.

Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes

V. Gandin, A. Kellett, C. Marzano, 2019, JBIC Journal of Biological Inorganic Chemistry.

Use of Sublimation Catalysis and Polycrystalline Powder Templates for Polymorph Control of Gas Phase Crystallization

M. Mahon, P. McArdle, A. Erxleben, 2018 .

Bis(purine) Complexes of trans-a2PtII: Preparation and X-ray Structures of Bis(9-methyladenine) and Mixed 9-Methyladenine, 9-Methylguanine Complexes and Chemistry Relevant to Metal-Modified Nucleobase Triples and Quartets

B. Lippert, A. Erxleben, A. Schreiber, 1996 .

Association patterns of platinated purine nucleobases in metal-modified pairs and triples.

B. Costisella, M. Roitzsch, B. Lippert, 2002, Inorganic chemistry.

B. Lippert, A. Erxleben, A. Schreiber, 1999 .

Sulfamerazine: Understanding the Influence of Slip Planes in the Polymorphic Phase Transformation through X-Ray Crystallographic Studies and ab Initio Lattice Dynamics.

J. Skelton, M. Warren, A. Pallipurath, 2015, Molecular pharmaceutics.

Coordination polymers of CdII and PbII derived from bipyridine-glycoluril: influence of metal-ion size and counter-ions.

A. Erxleben, Debamitra Chakravarty, A. Kumbhar, 2019, Acta crystallographica. Section C, Structural chemistry.

Copper(ii) mixed-ligand polypyridyl complexes with doxycycline - structures and biological evaluation.

F. Hoffmann, J. Obaleye, Ayesha Khan, 2016, Dalton transactions.

Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling.

V. Caron, A. Healy, O. Corrigan, 2013, Molecular pharmaceutics.

Crystallization from the Gas Phase: Morphology Control, Co-Crystal and Salt Formation

P. McArdle, A. Erxleben, Ciarán O’Malley, 2020, Proceedings.

Interaction of molybdocene dichloride with cysteine-containing peptides: coordination, regioselective hydrolysis, and intramolecular aminolysis.

Andrea Erxleben, A. Erxleben, 2005, Inorganic chemistry.