Yuanyuan Zhang

发表

Extruded Soluplus/SIM as an oral delivery system: characterization, interactions, in vitro and in vivo evaluations

Xing Tang, Bin Tian, Yanfei Luo, 2014, Drug delivery.

Investigation of potential toxic components based on the identification of Genkwa Flos chemical constituents and their metabolites by high-performance liquid chromatography coupled with a Q Exactive high-resolution benchtop quadrupole Orbitrap mass spectrometer.

Xiaohui Chen, Yuanyuan Zhang, Yu Chen, 2018, Journal of separation science.

A study of Semen Strychni-induced renal injury and herb-herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Integrative investigation of Semen Strychni nephrotoxicity and the protective effect of Radix Glycyrrhizae by a UPLC-MS/MS method based cell metabolomics strategy in HEK 293t cell lysates

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2015 .

Determination of 12 potential nephrotoxicity biomarkers in rat serum and urine by liquid chromatography with mass spectrometry and its application to renal failure induced by Semen Strychni.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2014, Journal of separation science.

Taurine Attenuates Calpain-2 Induction and a Series of Cell Damage via Suppression of NOX-Derived ROS in ARPE-19 Cells

Jiahong Wang, Yuanyuan Zhang, Shu-yue Ren, 2018, Oxidative medicine and cellular longevity.

Determination of a novel anticancer c-Met inhibitor LS-177 in rat plasma and tissues with a validated UPLC-MS/MS method: application to pharmacokinetics and tissue distribution study.

Xiaohui Chen, Kaishun Bi, Xing Tang, 2015, Biomedical chromatography : BMC.

In vitro metabolism of alisol A and its metabolites' identification using high-performance liquid chromatography-mass spectrometry.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Investigation of the mechanisms of Genkwa Flos hepatotoxicity by a cell metabolomics strategy combined with serum pharmacology in HL-7702 liver cells

Xiaohui Chen, Yuanyuan Zhang, Linjia Sun, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Discrimination of aqueous and vinegary extracts of Shixiao San using metabolomics coupled with multivariate data analysis and evaluation of anti-hyperlipidemic effect

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2014 .

Quantitative analysis of biomarkers of liver and kidney injury in serum and urine using ultra-fast liquid chromatography with tandem mass spectrometry coupled with a hydrophilic interaction chromatography column: Application to monitor injury induced by Euphorbiae pekinensis Radix.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2016, Journal of separation science.

Morphological and Crystalline Transitions in Monohydrous and Anhydrous Aripiprazole for a Long-Acting Injectable Suspension

Xinyi Tan, Xing Tang, Haibing He, 2017, AAPS PharmSciTech.

Supersaturation induced by Itraconazole/Soluplus® micelles provided high GI absorption in vivo

Xing Tang, Bin Tian, Haibing He, 2016 .

Theoretical Prediction of a Phase Diagram for Solid Dispersions

Xing Tang, Yu Zhang, Bin Tian, 2014, Pharmaceutical Research.

Preparation and evaluation of kaempferol-phospholipid complex for pharmacokinetics and bioavailability in SD rats.

Longshan Zhao, Xiaohui Chen, Kaishun Bi, 2015, Journal of pharmaceutical and biomedical analysis.

The hepatoprotective effect and mechanism of lotus leaf on liver injury induced by Genkwa Flos

Xiaohui Chen, Yuanyuan Zhang, Zhipeng Wang, 2020, The Journal of pharmacy and pharmacology.

Degradation kinetics of larotaxel and identification of its degradation products in alkaline condition

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2016, Journal of pharmaceutical analysis.

Nephrotoxicity evaluation of a new cembrane diterpene from Euphorbiae pekinensis Radix with HEK 293T cells and the toxicokinetics study in rats using a sensitive and reliable UFLC-MS/MS.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2016, Journal of pharmaceutical and biomedical analysis.

Effects of phospholipid complexes of total flavonoids from Persimmon (Diospyros kaki L.) leaves on experimental atherosclerosis rats.

Xiaohui Chen, Jingming Jia, Yuanyuan Zhang, 2016, Journal of ethnopharmacology.

The comparative pharmacokinetics of four bioactive ingredients after administration of Ramulus Cinnamomi-Radix Glycyrrhizae herb pair extract, Ramulus Cinnamomi extract and Radix Glycyrrhizae extract.

Longshan Zhao, Xiaohui Chen, Kaishun Bi, 2016, Biomedical chromatography : BMC.

LC-MS method for determination and pharmacokinetic study of chimaphilin in rat plasma after oral administration of the traditional Chinese medicinal preparation Lu xian cao decoction.

Xiaohui Chen, Kaishun Bi, Chul-Sa Kim, 2006, Biological & pharmaceutical bulletin.

Determination of depression biomarkers in rat plasma by liquid chromatography-mass spectrometry for the study of the antidepressant effect of Zhi-Zi-Hou-Po decoction on rat model of chronic unpredictable mild stress.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Inhibition of Starvation-Triggered Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in ARPE-19 Cells by Taurine through Modulating the Expression of Calpain-1 and Calpain-2

Yuanyuan Zhang, Shu-yue Ren, Zhouhai Zhang, 2017, International journal of molecular sciences.

Simultaneous Quantification of 13 Compounds in Guanxin Shutong Capsule by HPLC Method.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2016, Journal of chromatographic science.

Comparative pharmacokinetics of cyclophosphamide administration alone and combination with vitamin B6 in rats.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2015, Biomedical chromatography : BMC.

Development of quercetin-phospholipid complex to improve the bioavailability and protection effects against carbon tetrachloride-induced hepatotoxicity in SD rats.

Xiaohui Chen, G. Hu, Jingming Jia, 2016, Fitoterapia.

Cell-Based Screening Identifies the Active Ingredients from Traditional Chinese Medicine Formula Shixiao San as the Inhibitors of Atherosclerotic Endothelial Dysfunction

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2015, PloS one.

Determination of larotaxel and its metabolites in rat plasma by liquid chromatography-tandem mass spectrometry: application for a pharmacokinetic study.

Xiaohui Chen, Kaishun Bi, Xing Tang, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Evaluation of the indicative roles of seven potential biomarkers on hepato-nephrotoxicity induced by Genkwa Flos.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2014, Journal of ethnopharmacology.

Development of a UPLC–MS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study

Longshan Zhao, Xiaohui Chen, Kaishun Bi, 2017, Journal of pharmaceutical analysis.

Determination of 6258-70, a new semi-synthetic taxane, in rat plasma and tissues: Application to the pharmacokinetics and tissue distribution study☆

Longshan Zhao, Xiaohui Chen, Kaishun Bi, 2016, Journal of pharmaceutical analysis.

Reversible piezofluorochromism of a triphenylamine-based benzothiazole derivative with a strong fluorescence response to volatile acid vapors

Yuanyuan Zhang, Gang Li, Peng Yang, 2017 .

The absolute bioavailability investigation of LS177 in rats using ultra-performance liquid chromatography-tandem mass spectrometry.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2015, Drug testing and analysis.

Xiaohui Chen, Kaishun Bi, Yuanyuan Zhang, 2016, Journal of separation science.