M. Font

发表

Nanoaggregation of inclusion complexes of glibenclamide with cyclodextrins.

J. Irache, D. Lucio, M. Font, 2017, International journal of pharmaceutics.

Structural variations on antitumour agents derived from bisacylimidoselenocarbamate. A proposal for structure-activity relationships based on the analysis of conformational behaviour.

E. Ibáñez, Elena Lizarraga, C. Sanmartín, 2013, European journal of medicinal chemistry.

Indoles and pyridazino[4,5-b]indoles as nonnucleoside analog inhibitors of HIV-1 reverse transcriptase

J. Lasarte, F. Borrás, P. Sarobe, 1995 .

Methylselenol release as a cytotoxic tool: a study of the mechanism of the activity achieved by two series of methylselenocarbamate derivatives.

E. González-Peñas, C. Sanmartín, M. Font, 2018, Metallomics : integrated biometal science.

Molecular descriptors calculation as a tool in the analysis of the antileishmanial activity achieved by two series of diselenide derivatives. An insight into its potential action mechanism.

C. Sanmartín, S. Espuelas, M. Font, 2015, Journal of molecular graphics & modelling.

Advanced HIV Infection Treated with Zidovudine Monotherapy: Lifetime Values of Absolute Cost—Effectiveness as a Pharmacoeconomic Reference for Future Studies Evaluating Antiretroviral Combination Treatments

A. Messori, S. Trippoli, M. Font, 1997, The Annals of pharmacotherapy.

Novel Heteroaryl Selenocyanates and Diselenides as Potent Antileishmanial Agents

M. Toro, P. Nguewa, C. Sanmartín, 2016, Antimicrobial Agents and Chemotherapy.

Synthesis and Biological Evaluation of Heteroaryldiamides and Heteroaryldiamines as Cytotoxic Agents, Apoptosis Inducers and Caspase‐3 Activators

J. García-Foncillas, E. Cubedo, L. Cordeu, 2006, Archiv der Pharmazie.

Cytotoxic and proapototic activities of imidoselenocarbamate derivatives are dependent on the release of methylselenol.

E. Ansó, Elena Lizarraga, M. Font, 2012, Chemical research in toxicology.

New Indole and Pyridazinoindole Analogs — Synthesis and Study as Inhibitors of Phosphodiesterases and as Inhibitors of Blood Platelet Aggregation

A. Monge, M. Font, J. Martínez-Irujo, 1995, Archiv der Pharmazie.

A novel class of cardiotonic agents: synthesis and biological evaluation of pyridazino[4,5-b]indoles with cyclic AMP phosphodiesterases inhibiting properties.

A. Monge, M. Font, I. Aldana, 1993, Journal of pharmaceutical sciences.

New 4‐Amino‐7,8‐dimethoxy‐5h‐pyrimido[5,4‐b]indole Derivatives: Synthesis and Studies as Inhibitors of Phosphodiesterases

A. Monge, M. Font, E. Cenarruzabeitia, 1993, Archiv der Pharmazie.

New Indole and Triazino[5,4‐b]indol‐4‐one Derivatives: Synthesis and Studies as Inotropics and Inhibitors of Blood Platelet Aggregation

A. Monge, M. Font, I. Aldana, 1992, Archiv der Pharmazie.

New 5H-1,2,4-triazino[5,6-b]indole and aminoindole derivatives. Synthesis and studies as inhibitors of blood platelet aggregation, anti-hypertensive agents and thromboxane synthetase inhibitors

A. Monge, M. Font, J. Palop, 1991 .

New derivatives of 5H-pyridazino (4,5-b) indole and 1,2,4-triazino (4,5-a) indole and related compounds as inhibitors of blood platelet aggregation, anti-hypertensive agents and thromboxane synthetase inhibitors

A. Monge, M. Font, E. Fernández‐Álvarez, 1988 .

Inotropic and Chronotropic Effects of 4‐(4′‐n‐Butylaniline)‐7,8‐dimethoxy‐5H‐pyrimido[5,4–b]indole in Guinea‐pig Atria

A. Monge, M. Font, E. Cenarruzabeitia, 1995, The Journal of pharmacy and pharmacology.

Inclusion Complexes of Rifampicin with Native and Derivatized Cyclodextrins: In Silico Modeling, Formulation, and Characterization

Eneko Larrañeta, Juan Domínguez-Robles, R. Donnelly, 2021, Pharmaceuticals.

Supramolecular structure of glibenclamide and β-cyclodextrins complexes.

J. Irache, D. Lucio, M. Font, 2017, International journal of pharmaceutics.

Topological and quantum molecular descriptors as effective tools for analyzing cytotoxic activity achieved by a series of (diselanediyldibenzene-4,1-diylnide)biscarbamate derivatives.

C. Sanmartín, M. Font, D. Plano, 2017, Journal of molecular graphics & modelling.

Selenium and clinical trials: new therapeutic evidence for multiple diseases.

C. Sanmartín, M. Font, D. Plano, 2011, Current medicinal chemistry.

Bisacylimidoselenocarbamates cause G2/M arrest associated with the modulation of CDK1 and Chk2 in human breast cancer MCF-7 cells.

C. Sanmartín, I. Encío, M. Font, 2013, Current medicinal chemistry.

Selenocyanates and diselenides: a new class of potent antileishmanial agents.

C. Sanmartín, A. Jiménez-Ruiz, M. Font, 2011, European journal of medicinal chemistry.

New insights into the structural requirements for pro-apoptotic agents based on 2,4-diaminoquinazoline, 2,4-diaminopyrido[2,3-d]pyrimidine and 2,4-diaminopyrimidine derivatives.

Álvaro González, C. Sanmartín, M. Font, 2011, European journal of medicinal chemistry.

Synthesis and biological evaluation of new symmetrical derivatives as cytotoxic agents and apoptosis inducers.

J. García-Foncillas, E. Cubedo, L. Cordeu, 2005, Bioorganic & medicinal chemistry.

The role of imidazole and benzimidazole heterocycles in Chagas disease: A review.

M. Font, S. Pérez-Silanes, Verónica Alcolea, 2020, European journal of medicinal chemistry.

Argentine plant extracts active against polymerase and ribonuclease H activities of HIV‐1 reverse transcriptase

J. Lasarte, M. Cuevas, M. Sanromán, 1999, Phytotherapy research : PTR.

Novel hybrid selenosulfonamides as potent antileishmanial agents.

P. Nguewa, C. Sanmartín, Kilian Jesús Gutiérrez, 2014, European journal of medicinal chemistry.

Assessment of β-lapachone loaded in lecithin-chitosan nanoparticles for the topical treatment of cutaneous leishmaniasis in L. major infected BALB/c mice.

J. Irache, E. Larrea, C. Sanmartín, 2015, Nanomedicine : nanotechnology, biology, and medicine.

Structure-activity relationships in quinoline Reissert derivatives with HIV-1 reverse transcriptase inhibitory activity.

A. Monge, M. Font, B. Heras, 1997, Drug design and discovery.

Biological profile of new apoptotic agents based on 2,4-pyrido[2,3-d]pyrimidine derivatives.

E. Bandrés, J. García-Foncillas, E. Cubedo, 2007, Bioorganic & medicinal chemistry.

Synthesis and anti-HIV-1 activities of new pyrimido[5,4-b]indoles.

J. Lasarte, F. Borrás, P. Sarobe, 1999, Farmaco.

Sulfur and selenium derivatives of quinazoline and pyrido[2,3-d]pyrimidine: synthesis and study of their potential cytotoxic activity in vitro.

C. Sanmartín, I. Encío, M. Font, 2012, European journal of medicinal chemistry.

Synthesis and evaluation of new Reissert analogs as HIV-1 RT inhibitors. 2. Benzo[f]quinoline and pyridine derivatives.

J. Lasarte, F. Borrás, C. San Martín, 1997, Drug design and discovery.

Antihypertensive agents: pyridazino (4,5-b)indole derivatives.

M. Font, I. Aldana, P. Parrado, 1982, Journal of pharmaceutical sciences.

Synthesis and Pharmacological Screening of Several Aroyl and Heteroaroyl Selenylacetic Acid Derivatives as Cytotoxic and Antiproliferative Agents

C. Prior, A. Calvo, C. Sanmartín, 2009, Molecules.

1-Hydrazino-4-(3,5-dimethyl-1-pyrazolyl)-5H-pyridazino[4,5-b]indole. A new antihypertensive agent

A. Monge, M. Font, I. Aldana, 1991 .

A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer.

C. Cruchaga, E. Ansó, A. Rouzaut, 2007, The Biochemical journal.

Synthesis and Biological Evaluation of 2,4,6‐Functionalized Derivatives of Pyrido[2,3‐d]pyrimidines as Cytotoxic Agents and Apoptosis Inducers

J. García-Foncillas, E. Cubedo, L. Cordeu, 2007, Archiv der Pharmazie.

Synthesis and antiproliferative activity of novel methylselenocarbamates.

C. Sanmartín, I. Encío, M. Font, 2014, European journal of medicinal chemistry.

Synthesis and antiproliferative activity of novel selenoester derivatives.

C. Prior, C. Jacob, A. Calvo, 2014, European journal of medicinal chemistry.

Synthesis and in vitro Anticancer Activities of some Selenadiazole Derivatives

C. Sanmartín, I. Encío, M. Font, 2010, Archiv der Pharmazie.

Structural characteristics of phosphoramide derivatives as urease inhibitors. Requirements for activity.

J. García-Mina, C. Sanmartín, M. Font, 2008, Journal of agricultural and food chemistry.

Design, synthesis, and biological evaluation of phosphoramide derivatives as urease inhibitors.

J. García-Mina, C. Sanmartín, M. Font, 2008, Journal of agricultural and food chemistry.

Two ellagitannins from the leaves of Terminalia triﬂora with inhibitory activity on HIV‐1 reverse transcriptase

A. Monge, M. Font, V. Martino, 2004, Phytotherapy research : PTR.

New symmetrical quinazoline derivatives selectively induce apoptosis in human cancer cells

E. Bandrés, E. Cubedo, R. Malumbres, 2006, Cancer biology & therapy.

Effect of the synthetic polyamine N,N′-bis-(3-aminopropyl) cyclohexane-1,4-diamine (DCD) on rat spinal cord nociceptive transmission

C. Paeile, M. Font, N. Bilbeny, 2004, Brain Research.

Novel structural insights for imidoselenocarbamates with antitumoral activity related to their ability to generate methylselenol.

E. Ansó, C. Sanmartín, M. Font, 2012, Bioorganic & medicinal chemistry.

The enzyme inducers 3-methylcholanthrene and phenobarbital affect the activities of glucocorticoid hormone-regulated enzymes in rat liver and kidney.

L. Weber, M. Boll, A. Stampfl, 1998, Toxicology.

Antihypertensive and vasodilator effect of A-80b, a new pyridazino indole derivative.

A. Monge, M. Font, I. Aldana, 1992, European journal of pharmacology.

Selective thromboxane synthetase inhibitors and antihypertensive agents. New derivatives of 4-hydrazino-5H-pyridazino[4,5-b]indole, 4-hydrazinopyridazino[4,5-a]indole, and related compounds.

A. Monge, M. Font, E. Fernández‐Álvarez, 1987, Journal of medicinal chemistry.

Kinase regulation by sulfur and selenium containing compounds.

C. Sanmartín, M. Font, D. Plano, 2011, Current cancer drug targets.

Synthesis and antiproliferative activity of novel symmetrical alkylthio- and alkylseleno-imidocarbamates.

E. Ibáñez, C. Prior, A. Calvo, 2011, European journal of medicinal chemistry.

Innovative lead compounds and formulation strategies as newer kinetoplastid therapies.

J. Irache, P. Nguewa, C. Sanmartín, 2012, Current medicinal chemistry.

Thermal stability and decomposition of sulphur and selenium compounds

Elena Lizarraga, C. Sanmartín, M. Font, 2009 .

New 5H-pyridazino[4,5-b]indole derivatives. Synthesis and studies as inhibitors of blood platelet aggregation and inotropics.

A. Monge, M. Font, I. Aldana, 1991, Journal of medicinal chemistry.

New 5H‐Pyridazino(4,5‐b)indole Derivatives. Synthesis and Studies as Inhibitors of Blood Platelet Aggregation and Inotropics.

A. Monge, M. Font, I. Aldana, 1992 .

Prioritization of Mycotoxins Based on Their Genotoxic Potential with an In Silico-In Vitro Strategy

A. Vettorazzi, E. González-Peñas, A. López de Cerain, 2021, Toxins.

Inhibitory effect against polymerase and ribonuclease activities of HIV‐reverse transcriptase of the aqueous leaf extract of Terminalia triflora

J. Lasarte, M. Sanromán, P. López, 2002, Phytotherapy research : PTR.

A new polyamine derivative, a structural analog of spermine, with in vivo activity as an inhibitor of ethanol appetite.

C. Sanmartín, C. Paeile, M. Font, 2005, Bioorganic & medicinal chemistry.

Effect of natural and synthetic polyamines on ethanol intake in UChB drinker rats.

C. Paeile, M. Font, N. Bilbeny, 2005, Alcohol.

A dihydroselenoquinazoline inhibits S6 ribosomal protein signalling, induces apoptosis and inhibits autophagy in MCF-7 cells.

C. Sanmartín, I. Encío, M. Font, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Selective Thromboxane Synthetase Inhibitors and Antihypertensive Agents. New Derivatives of 4-Hydrazino-5H-pyridazino(4,5-b)indole, 4-Hydrazinopyridazino(4,5-a)indole, and Related Compounds.

A. Monge, M. Font, E. Fernández‐Álvarez, 1987 .

Action of metadoxine on isolated human and rat alcohol and aldehyde dehydrogenases. Effect on enzymes in chronic ethanol-fed rats.

X. Parés, A. Moreno, M. Font, 1991, Methods and findings in experimental and clinical pharmacology.

Sulfur and selenium derivatives of quinazoline and pyrido[2,3-d]pyrimidine: synthesis and study of their potential cytotoxic activity in vitro.

C. Sanmartín, I. Encío, M. Font, 2012, European journal of medicinal chemistry.

Molecular symmetry: a structural property frequently present in new cytotoxic and proapoptotic drugs.

C. Sanmartín, M. Font, J. Palop, 2006, Mini reviews in medicinal chemistry.

Preparation method Type of cyclodextrin Drug-cyclodextrin ratio

J. Irache, D. Lucio, M. Font, 2017 .

Synthesis and Biological Evaluation of 2,4,6‐Functionalized Derivatives of Pyrido[2,3‐d]pyrimidines as Cytotoxic Agents and Apoptosis Inducers

J. García-Foncillas, E. Cubedo, C. Sanmartín, 2007, Archiv der Pharmazie.

Synthesis and evaluation of new Reissert analogs as HIV-1 reverse transcriptase inhibitors. 1. Quinoline and quinoxaline derivatives.

J. Lasarte, F. Borrás, P. Sarobe, 1997, Drug design and discovery.

Topological and quantum molecular descriptors as effective tools for analyzing cytotoxic activity achieved by a series of (diselanediyldibenzene-4,1-diylnide)biscarbamate derivatives.

C. Sanmartín, M. Font, D. Plano, 2017, Journal of molecular graphics & modelling.

Effect of ME-3451-106, an aqueous extract of Stichaster striatus with inhibitory activity of voluntary alcohol intake, in genetically drinker rats: Isolation and identification of the active fraction.

C. Paeile, M. Font, N. Bilbeny, 2006, Journal of ethnopharmacology.