J. Beech

发表

A simple, open and extensible gating Control unit for cardiac and respiratory synchronisation control in small animal MRI and demonstration of its robust performance in steady-state maintained CINE-MRI

B. Vojnovic, V. Kersemans, D. Allen, 2021, Magnetic resonance imaging.

A chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke

S. Williams, T. Meade, S. Williams, 2009, NeuroImage.

Subcutaneous tumor volume measurement in the awake, manually restrained mouse using MRI

B. Cornelissen, V. Kersemans, S. Smart, 2013, Journal of magnetic resonance imaging : JMRI.

Anaesthetic Impairment of Immune Function Is Mediated via GABAA Receptors

J. Trowsdale, D. Menon, A. J. Thompson, 2011, PloS one.

Neuroprotection in Ischemia–Reperfusion Injury: An Antiinflammatory Approach Using a Novel Broad-Spectrum Chemokine Inhibitor

Steven C. R. Williams, D. Menon, D. Grainger, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Early-stage 11C-Flumazenil PET predicts day-14 selective neuronal loss in a rodent model of transient focal cerebral ischemia

J. Baron, D. Menon, T. Fryer, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Ultrasonography-guided intracardiac injection: an improvement for quantitative brain colonization assays.

R. Muschel, J. Beech, L. Balathasan, 2013, The American journal of pathology.

Benzodiazepine Binding Site Occupancy by the Novel GABAA Receptor Subtype-Selective Drug 7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in Rats, Primates, and Humans

J. Baron, T. Fryer, D. Wong, 2010, Journal of Pharmacology and Experimental Therapeutics.

Comparison of Lorazepam [7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one] Occupancy of Rat Brain γ-Aminobutyric AcidA Receptors Measured Using in Vivo [3H]Flumazenil (8-Fluoro 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester)

J. Baron, T. Fryer, J. Atack, 2007, Journal of Pharmacology and Experimental Therapeutics.

Imaging post-ischaemic cellular changes using 11C-flumazenil & microPET following temporary distal MCA occlusion in the spontaneous hypertensive rat (SHR)

J. Baron, D. Menon, T. Fryer, 2005 .

MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform

M. Gaze, B. Vojnovic, M. Hill, 2016, The British journal of radiology.

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

N. Morrell, Jingxu Guo, D. Grainger, 2020, Nature Communications.

Automated MicroSPECT/MicroCT Image Analysis of the Mouse Thyroid Gland.

C. Menq, K. Powell, S. Jhiang, 2017, Thyroid : official journal of the American Thyroid Association.

Comparison of Lorazepam [7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2 H -1,4-benzodiazepin-2-one] Occupancy of Rat Brain (cid:1) -Aminobutyric Acid A Receptors Measured Using in Vivo [ 3 H]Flumazenil (8-Fluoro 5,6-dihydro-5-methyl-6-oxo-4 H -imidazo[1,5- a ][1,4]benzodiazepine-3-carboxylic Ac

J. Baron, T. Fryer, J. Atack, 2007 .

Comparison of Lorazepam Occupancy of Rat Brain GABAA Receptors Measured Using In Vivo [H]Flumazenil Binding and [C]Flumazenil microPET

J. Baron, T. Fryer, J. Atack, 2006 .

Bicarbonate and cytoplasmic pH

H. F. Woods, R. Unwin, K. Buckler, 1990, The Lancet.

Bicarbonate in the treatment of metabolic acidosis: effects on hepatic intracellular pH, gluconeogenesis, and lactate disposal in rats.

J. Beech, R. Iles, R. D. Cohen, 1993, Metabolism: clinical and experimental.

Haemodynamic and metabolic effects in diabetic ketoacidosis in rats of treatment with sodium bicarbonate or a mixture of sodium bicarbonate and sodium carbonate

J. Beech, R. Iles, T. Going, 1995, Diabetologia.

The effects of sodium bicarbonate and a mixture of sodium bicarbonate and carbonate ("Carbicarb") on skeletal muscle pH and hemodynamic status in rats with hypovolemic shock.

S. Williams, J. Beech, R. Iles, 1994, Metabolism: clinical and experimental.

Journal of Cerehral Blood Flow and Metabolism a Temporal Mri Assessment of Neuropathology after Transient Middle Cerebral Artery Occlusion in the Rat: Correlations with Behavior

H. Hodges, A. Hunter, D. Virley, 2022 .

MRI assessment of the blood-brain barrier in a hamster model of scrapie.

Jimmy D Bell, I. Cox, J. Hope, 1995, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.

Cerebroprotective Effect of the Nitric Oxide Synthase Inhibitors, 1-(2-Trifluoromethylphenyl) Imidazole and 7-Nitro Indazole, after Transient Focal Cerebral Ischemia in the Rat

K. J. Escott, B. Meldrum, P. Bath, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Further characterisation of a thromboembolic model of stroke in the rat

Steven C. R. Williams, D. Menon, A. A. Parsons, 2001, Brain Research.

miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.

M. Gorospe, A. Harris, R. Muschel, 2011, Molecular cell.

Resolution of Stroke Deficits Following Contralateral Grafts of Conditionally Immortal Neuroepithelial Stem Cells

John S. Beech, R. P. Stroemer, H. Hodges, 2001, Stroke.

Recruitment of a myeloid cell subset (CD11b/Gr1mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis *

R. Muschel, J. Im, D. Allen, 2013, Hepatology.

Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain

Steven C. R. Williams, B. Meldrum, P. Bath, 2001, Brain Research.

Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth

A. Harris, Wei Zhang, F. Buffa, 2016, Oncotarget.

Dual inhibition of the PI3K/mTOR pathway increases tumor radiosensitivity by normalizing tumor vasculature.

R. Muschel, J. Im, E. Fokas, 2012, Cancer research.

Delta-like ligand 4-notch blockade and tumor radiation response.

A. Harris, R. Muschel, J. Im, 2011, Journal of the National Cancer Institute.

Cd11b+ myeloid cells support hepatic metastasis through down‐regulation of angiopoietin‐like 7 in cancer cells

R. Muschel, V. Kersemans, D. Allen, 2015, Hepatology.

The MHP36 line of murine neural stem cells expresses functional CXCR1 chemokine receptors that initiate chemotaxis in vitro

D. Menon, D. Grainger, P. Mastroeni, 2007, Journal of Neuroimmunology.

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

N. Morrell, Jingxu Guo, D. Grainger, 2020, Nature Communications.

Hepatic intracellular pH in Vivo using F‐quene 1 and 19F NMR spectroscopy

J. Beech, R. Iles, R A Iles, 1991, Magnetic resonance in medicine.

Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma.

T. H. van der Kwast, W. Lam, I. Jurisica, 2012, The Journal of clinical investigation.

The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions

D. Engelman, A. Harris, A. Moshnikova, 2015, Proceedings of the National Academy of Sciences.

Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

A. Harris, B. Slotman, R. Muschel, 2016, Oncotarget.

A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation

D. Wang, Peter S. Jones, Franklin I. Aigbirhio, 2012, NeuroImage.

Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis

R. Muschel, J. Im, D. Allen, 2013, Oncoimmunology.

The neuronal nitric oxide synthase inhibitor, TRIM, as a neuroprotective agent: effects in models of cerebral ischaemia using histological and magnetic resonance imaging techniques

Steven C. R. Williams, L. Gregory, M. O'Neill, 2003, Brain Research.

A resistive heating system for homeothermic maintenance in small animals

Stuart Gilchrist, John S. Beech, Veerle Kersemans, 2015, Magnetic resonance imaging.

Multi-modal characterisation of the neocortical clip model of focal cerebral ischaemia by MRI, behaviour and immunohistochemistry

John S. Beech, Andrew S. Lowe, A. Lowe, 2007, Brain Research.

Late changes in blood–brain barrier permeability in a rat tMCAO model of stroke detected by gadolinium-enhanced MRI

S. Williams, D. Cash, M. Mesquita, 2020, Neurological research.

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

D. Cash, G. Kartje, Barbara Haenzi, 2016, Journal of visualized experiments : JoVE.

Single-subject statistical mapping of acute brain hypoxia in the rat following middle cerebral artery occlusion: A microPET study

John S. Beech, Franklin I. Aigbirhio, Tim D. Fryer, 2011, Experimental Neurology.

The Development of Technology for Effective Respiratory-Gated Irradiation Using an Image-Guided Small Animal Irradiator

M A Hill, J M Thompson, A Kavanagh, 2017, Radiation Research.

Prospective gating control for highly efficient cardio-respiratory synchronised short and constant TR MRI in the mouse

Michael Brady, Paul Kinchesh, Stuart Gilchrist, 2018, Magnetic resonance imaging.

Improving In Vivo High-Resolution CT Imaging of the Tumour Vasculature in Xenograft Mouse Models through Reduction of Motion and Bone-Streak Artefacts

J. Schnabel, B. Irving, R. Muschel, 2015, PloS one.

Imaging of Brain Hypoxia in Permanent and Temporary Middle Cerebral Artery Occlusion in the Rat using 18F-Fluoromisonidazole and Positron Emission Tomography: A Pilot Study

Young T. Hong, Jean-Claude Baron, David K Menon, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Parametric Mapping of [18F]Fluoromisonidazole Positron Emission Tomography using Basis Functions

Young T. Hong, Jean-Claude Baron, John S Beech, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat

D. Wang, Peter S. Jones, David K. Menon, 2010, NeuroImage.

Glucose utilization by interscapular brown adipose tissue in vivo during nutritional transitions in the rat.

M. Holness, M. Sugden, J. Beech, 1991, The Biochemical journal.

Myeloid cells are recruited by liver metastases and aid their development

R. Muschel, D. Allen, S. Smart, 2013 .

GSK249320, A Monoclonal Antibody Against the Axon Outgrowth Inhibition Molecule Myelin-Associated Glycoprotein, Improves Outcome of Rodents with Experimental Stroke

S. Cramer, S. Williams, D. Cash, 2016, Journal of neurology and experimental neuroscience.

Cd11b+ myeloid cells support hepatic metastasis through down‐regulation of angiopoietin‐like 7 in cancer cells

R. Muschel, V. Kersemans, D. Allen, 2015, Hepatology.

Recruitment of a myeloid cell subset (CD11b/Gr1mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis *

R. Muschel, J. Im, D. Allen, 2013, Hepatology.

19F n.m.r. indicators of hepatic intracellular pH in vivo

J. Beech, R. Iles, 1987 .

miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.

M. Gorospe, A. Harris, R. Muschel, 2011, Molecular cell.

Small animal, whole brain fMRI: Innocuous and nociceptive forepaw stimulation

A. Lowe, S. Williams, J. Beech, 2007, NeuroImage.