H. Eggenweiler

发表

Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90.

Astrid Zimmermann, Djordje Musil, Hans-Michael Eggenweiler, 2012, Bioorganic & medicinal chemistry letters.

A New Monolithic‐Type HPLC Column For Fast Separations

K. Nakanishi, D. Lubda, H. Minakuchi, 2000 .

Cell survival and protein secretion associated with Golgi integrity in response to Golgi stress‐inducing agents

J. Reiling, H. Eggenweiler, R. Lindemann, 2017, Traffic.

Linkers for solid-phase synthesis of small molecules: coupling and cleavage techniques

H. Eggenweiler, 1998 .

Discovery and Structure–Activity Relationships of N‐Aryl 6‐Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors

M. Jurzak, M. Nowak, M. Kujawa, 2018, ChemMedChem.

Hsp90 hemmende triazolderivate

H. Eggenweiler, M. Wolf, 2006 .

Functional Analysis of Hsp70 Inhibitors

M. Mayer, B. Bukau, D. Musil, 2013, PloS one.

Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

R. Wade, M. Frech, J. Bomke, 2017, Nature Communications.

A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.

M. Kaiser, H. Meyer, Johannes van den Boom, 2018, Angewandte Chemie.

Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

R. Wade, M. Frech, P. Matias, 2017, Nature Communications.

1,3-dihydro-isoindole derivatives

H. Buchstaller, H. Eggenweiler, C. Sirrenberg, 2007 .

Predicting Residence Time and Drug Unbinding Pathway through Scaled Molecular Dynamics

Matteo Masetti, Maurizio Recanatini, Andrea Cavalli, 2018, J. Chem. Inf. Model..

Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties.

M. Jurzak, M. Nowak, M. Kujawa, 2019, Bioorganic & medicinal chemistry letters.

Discovery and Structure-Activity Relationships of N-Aryl 6-Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors.

M. Jurzak, M. Nowak, M. Kujawa, 2018 .

Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors.

G. Ecker, M. Frech, D. Musil, 2018, Journal of Medicinal Chemistry.

Photoredox Csp3−Csp2 Reductive Cross‐Couplings of Cereblon Ligands for PROTAC Linker Exploration in Batch and Flow

Jason D. Williams, C. Kappe, H. Eggenweiler, 2022, ChemCatChem.

Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 4

M. Nowak, M. Mikulski, H. Eggenweiler, 2019 .

Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations

D. Musil, H. Eggenweiler, M. Lehmann, 2019 .

A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.

M. Kaiser, Johannes van den Boom, F. Kaschani, 2018, Angewandte Chemie.

A novel strategy for ADME screening of prodrugs: combined use of serum and hepatocytes to integrate bioactivation and clearance, and predict exposure to both active and prodrug to the systemic circulation.

J. März, N. Hewitt, H. Buchstaller, 2014, Journal of pharmaceutical sciences.