R S Obach

Nonspecific binding to microsomes: impact on scale-up of in vitro intrinsic clearance to hepatic clearance as assessed through examination of warfarin, imipramine, and propranolol.

R. Obach, R S Obach, 1997, Drug metabolism and disposition: the biological fate of chemicals.

The effect of CP‐99994 on the responses to provocative motion in the cat

R. Obach, S. Mclean, R S Obach, 1997, British journal of pharmacology.

The prediction of human clearance from hepatic microsomal metabolism data.

R. Obach, R S Obach, 2001, Current opinion in drug discovery & development.

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

R. Obach, R S Obach, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression.

R. Obach, R S Obach, 2000, The Journal of pharmacology and experimental therapeutics.

Three-dimensional quantitative structure activity relationship computational approaches for prediction of human in vitro intrinsic clearance.

S. Ekins, R. Obach, R S Obach, 2000, The Journal of pharmacology and experimental therapeutics.

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

D J Rance, R. Obach, F. Macintyre, 1997, The Journal of pharmacology and experimental therapeutics.

Evaluation of Various Static In Vitro–In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug

J Snoeys, S D Hall, L Zhang, 2014, Clinical pharmacology and therapeutics.