J Schoepfer

Structure-based design of compounds inhibiting Grb2-SH2 mediated protein-protein interactions in signal transduction pathways.

P. Furet, C. García-echeverría, H. Fretz, 2000, Current pharmaceutical design.

Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain.

P. Furet, C. García-echeverría, H. Fretz, 1997, Journal of medicinal chemistry.

Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain.

P. Furet, C. García-echeverría, H. Fretz, 1998, Journal of medicinal chemistry.

Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic.

P. Furet, C. García-echeverría, J. Schoepfer, 1999, Journal of medicinal chemistry.