C. Mack

发表

Transcriptional and post-transcriptional regulation of the blood pressure-associated Rho-specific GAP, ARHGAP42.

Kevin D Mangum, E. Freeman, Justin C Magin, 2019, American journal of physiology. Heart and circulatory physiology.

Sphingosine 1-Phosphate Stimulates Smooth Muscle Cell Differentiation and Proliferation by Activating Separate Serum Response Factor Co-factors*

Joan M. Taylor, C. Mack, K. Lockman, 2004, Journal of Biological Chemistry.

Signaling mechanisms that regulate smooth muscle cell differentiation.

C. Mack, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Druggable targets in the Rho pathway and their promise for therapeutic control of blood pressure

Kevin D Mangum, Joan M. Taylor, C. Mack, 2019, Pharmacology & therapeutics.

Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).

C. Vaziri, M. Rojas, Joan M. Taylor, 2014, Journal of molecular and cellular cardiology.

FRNK Expression Promotes Smooth Muscle Cell Maturation During Vascular Development and After Vascular Injury

J. Parsons, M. Rojas, Haruko Hayasaka, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Regulation of myocardin factor protein stability by the LIM-only protein FHL2.

Joan M. Taylor, C. Mack, J. S. Hinson, 2008, American journal of physiology. Heart and circulatory physiology.

Diaphanous 1 and 2 Regulate Smooth Muscle Cell Differentiation by Activating the Myocardin-Related Transcription Factors

D. Staus, Joan M. Taylor, C. Mack, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Sphingosine 1-Phosphate Receptor 2 Signals Through Leukemia-Associated RhoGEF (LARG), to Promote Smooth Muscle Cell Differentiation

D. Staus, Joan M. Taylor, C. Mack, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth*♦

D. Cyr, Qiang Zhu, Joan M. Taylor, 2016, The Journal of Biological Chemistry.

Nuclear RhoA signaling regulates MRTF-dependent SMC-specific transcription.

D. Staus, Laura Weise-Cross, Kevin D Mangum, 2014, American journal of physiology. Heart and circulatory physiology.

Formin Homology Domain–Containing Protein 1 Regulates Smooth Muscle Cell Phenotype

D. Staus, Joan M. Taylor, C. Mack, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain.

D. Staus, Joan M. Taylor, C. Mack, 2011, The Biochemical journal.

Focal Adhesion Kinase Regulates Smooth Muscle Cell Recruitment to the Developing Vasculature

M. Majesky, Joan M. Taylor, C. Mack, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Smooth muscle alpha-actin CArG elements coordinate formation of a smooth muscle cell-selective, serum response factor-containing activation complex.

G. Owens, C. Mack, M. M. Thompson, 2000, Circulation research.

Substitution of the Degenerate Smooth Muscle (SM) α-Actin CC(A/T-rich)6GG Elements with c-fos Serum Response Elements Results in Increased Basal Expression but Relaxed SM Cell Specificity and Reduced Angiotensin II Inducibility*

G. Owens, C. S. Madsen, C. Mack, 1998, The Journal of Biological Chemistry.

Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment

R. Schwartz, L. Reichardt, O. Smithies, 2007, Molecular and Cellular Biology.

FAK regulates cardiomyocyte survival following ischemia/reperfusion.

M. Rojas, Joan M. Taylor, C. Mack, 2009, Journal of molecular and cellular cardiology.

Myocyte-Restricted Focal Adhesion Kinase Deletion Attenuates Pressure Overload–Induced Hypertrophy

M. Rojas, L. Reichardt, Joan M. Taylor, 2006, Circulation research.

First Intron Promoter Regions ′ Within the 5-Actin Expression In Vivo Is Dependent on CArG Elements α Regulation of Smooth Muscle

G. Owens, C. Mack, 1999 .

Skeletal Muscle Differentiation and Fusion Are Regulated by the BAR-containing Rho-GTPase-activating Protein (Rho-GAP), GRAF1*

F. Conlon, Joan M. Taylor, C. Mack, 2011, The Journal of Biological Chemistry.

The LIM Protein Leupaxin Is Enriched in Smooth Muscle and Functions As an Serum Response Factor Cofactor to Induce Smooth Muscle Cell Gene Transcription

Joan M. Taylor, C. Mack, L. DiMichele, 2008, Circulation research.

and Response Factor Cofactor to Induce Smooth Muscle Cell Gene Transcription The LIM Protein Leupaxin Is Enriched in Smooth Muscle and Functions As an Serum

Joan M. Taylor, C. Mack, L. DiMichele, 2008 .

Selective Expression of an Endogenous Inhibitor of FAK Regulates Proliferation and Migration of Vascular Smooth Muscle Cells

J. Parsons, G. Owens, C. Regan, 2001, Molecular and Cellular Biology.

Transient Expression of FRNK Reveals Stage-Specific Requirement for Focal Adhesion Kinase Activity in Cardiac Growth

R. Schwartz, M. Rojas, Joan M. Taylor, 2009, Circulation research.

FRNK expression promotes smooth muscle cell maturation during vascular development and following vascular injury

M. Rojas, Haruko Hayasaka, T. Parsons, 2010 .

Quantifying sphingosine-1-phosphate-dependent activation of the RhoGTPases.

Joan M. Taylor, C. Mack, Matt D. Medlin, 2012, Methods in molecular biology.

GRAF1 promotes ferlin-dependent myoblast fusion.

E. McNally, Joan M. Taylor, C. Mack, 2014, Developmental biology.

Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest.

Joan M. Taylor, C. Mack, T. J. O’Neill, 2012, Journal of molecular and cellular cardiology.

S1P Receptor 2 Signals Through the RGS-RhoGEF, LARG, To Promote Smooth Muscle Cell Differentiation

D. Staus, Joan M. Taylor, C. Mack, 2010 .

Formin Homology Domain-Containing Protein 1 (FHOD1) Regulates Smooth Muscle Cell Phenotype

D. Staus, Joan M. Taylor, C. Mack, 2011 .

GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice

E. McNally, Joan M. Taylor, C. Mack, 2015, Skeletal Muscle.

Pyrroloquinoline quinone acts with flavin reductase to reduce ferryl myoglobin in vitro and protects isolated heart from re-oxygenation injury.

V. Massey, C. Mack, F. Xu, 1993, Biochemical and biophysical research communications.

Adhesion Stimulates Direct PAK1/ERK2 Association and Leads to ERK-dependent PAK1 Thr212 Phosphorylation*

Joan M. Taylor, C. Mack, Liisa J. Sundberg-Smith, 2005, Journal of Biological Chemistry.

Smooth Muscle Differentiation Marker Gene Expression Is Regulated by RhoA-mediated Actin Polymerization*

G. Owens, A. Somlyo, A. Somlyo, 2001, The Journal of Biological Chemistry.

Regulation of smooth muscle alpha-actin expression in vivo is dependent on CArG elements within the 5' and first intron promoter regions.

G. Owens, C. Mack, Christopher P. Mack, 1999, Circulation research.

An epigenetic clue to diabetic vascular disease.

C. Mack, 2008, Circulation research.

Genome-Wide RNAi Screen Identifies Regulators of Cardiomyocyte Necrosis.

J. Parker, Qiang Zhu, Joan M. Taylor, 2019, ACS pharmacology & translational science.

RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF

J. Rozenberg, Joan M. Taylor, C. Mack, 2018, Nucleic acids research.

RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF

J. Rozenberg, Joan M. Taylor, C. Mack, 2018, Nucleic acids research.

Regulation of smooth muscle differentiation by the myocardin family of serum response factor co‐factors

C. Mack, J. S. Hinson, Christopher P. Mack, 2005, Journal of thrombosis and haemostasis : JTH.

Characterization of Graf, the GTPase-activating Protein for Rho Associated with Focal Adhesion Kinase

J. Parsons, J. Hildebrand, M. Cox, 1998, The Journal of Biological Chemistry.

A role for focal adhesion kinase in vascular smooth muscle cell differentiation

Joan M. Taylor, C. Mack, Lee Mangiante, 2006 .

The Histone Demethylase, Jmjd1a, Interacts With the Myocardin Factors to Regulate SMC Differentiation Marker Gene Expression

Joan M. Taylor, C. Mack, K. Lockman, 2007, Circulation research.

DNA Methylation of a GC Repressor Element in the Smooth Muscle Myosin Heavy Chain Promoter Facilitates Binding of the Notch-Associated Transcription Factor, RBPJ/CSL1

J. Rozenberg, Joan M. Taylor, C. Mack, 2014, Arteriosclerosis, thrombosis, and vascular biology.

PKA-Dependent Phosphorylation of Serum Response Factor Inhibits Smooth Muscle–Specific Gene Expression

Joan M. Taylor, C. Mack, Alicia L. Blaker, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors.

Joan M. Taylor, C. Mack, K. Lockman, 2007, American journal of physiology. Heart and circulatory physiology.

An Endogenous Inhibitor of Focal Adhesion Kinase Blocks Rac1/JNK but Not Ras/ERK-dependent Signaling in Vascular Smooth Muscle Cells*

Joan M. Taylor, C. Mack, H. Bill, 2003, Journal of Biological Chemistry.

Molecular Regulation of the RhoGAP GRAF3 and Its Capacity to Limit Blood Pressure In Vivo

Joan M. Taylor, C. Mack, X. Bai, 2020, Cells.

A Primer on Repeated Sitting Exposure and the Cardiovascular System: Considerations for Study Design, Analysis, Interpretation, and Translation

Daniel P. Credeur, K. Stone, B. Barone Gibbs, 2021, Frontiers in Cardiovascular Medicine.

Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta.

M. Kadmiel, S. Espenschied, K. Caron, 2013, The Journal of clinical investigation.

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation

F. Conlon, Joan M. Taylor, C. Mack, 2010, Genesis.

Evidence that NADPH‐dependent methemoglobin reductase and administered riboflavin protect tissues from oxidative injury

A. Seekamp, G. Till, A. Betz, 1993, American journal of hematology.

Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility

Elaine L. Shelton, T. Furey, Kevin D Mangum, 2023, JCI insight.

The actin depolymerizing factor, Destrin, serves as a negative feedback inhibitor of smooth muscle cell differentiation.

Krsna V. Rangarajan, K. Liao, Joan M. Taylor, 2021, American journal of physiology. Heart and circulatory physiology.

Blood pressure–associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding

A. Viera, J. Schisler, C. Patterson, 2017, The Journal of clinical investigation.

Myocardial flavin reductase and riboflavin: a potential role in decreasing reoxygenation injury.

C. Mack, D. Hultquist, M. Shlafer, 1995, Biochemical and biophysical research communications.

GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure

O. Smithies, Oliver Smithies, Joan M Taylor, 2017, Small GTPases.

The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension

M. Rojas, O. Smithies, Joan M. Taylor, 2013, Nature Communications.

Inhibition of Diaphanous Formin Signaling In Vivo Impairs Cardiovascular Development and Alters Smooth Muscle Cell Phenotype

Laura Weise-Cross, Joan M. Taylor, C. Mack, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Targeted Focal Adhesion Kinase Activation in Cardiomyocytes Protects the Heart From Ischemia/Reperfusion Injury

M. Rojas, Joan M. Taylor, C. Mack, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Targeted Focal Adhesion Kinase Activation in Cardiomyocytes Protects the Heart From Ischemia/Reperfusion Injury

M. Rojas, Joan M. Taylor, C. Mack, 2012, Arteriosclerosis, thrombosis, and vascular biology.

PKA-Dependent Phosphorylation of Serum Response Factor Inhibits Smooth Muscle–Specific Gene Expression

Joan M. Taylor, C. Mack, Alicia L. Blaker, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Signaling mechanisms that regulate smooth muscle cell differentiation.

C. Mack, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Genome-Wide RNAi Screen Identi ﬁ es Regulators of Cardiomyocyte Necrosis

Joan M. Taylor, C. Mack, Zhaokang Cheng, 2022 .

GRAF1 Acts as a Downstream Mediator of Parkin to Regulate Mitophagy in Cardiomyocytes

C. Mack, Michelle Mendiola Pla, Matthew Combs, 2024, Cells.

GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis

J. Locasale, C. Mack, M. M. Pla, 2023, Nature communications.

GRAF1 Regulates Brown and Beige Adipose Differentiation and Function

Joan M. Taylor, C. Mack, M. Wabitsch, 2023, Research square.

Abstract 627: The Smooth Muscle-selective RhoGAP Graf3 Is A Critical Regulator Of Vascular Tone And Hypertension

J. Schisler, G. Stouffer, A. Oni‐Orisan, 2014, Hypertension.

The LIM Protein Leupaxin Is Enriched in Smooth Muscle and Functions As an Serum Response Factor Cofactor to Induce Smooth Muscle Cell Gene Transcription

Joan M. Taylor, C. Mack, L. DiMichele, 2008, Circulation research.

An epigenetic clue to diabetic vascular disease.

C. Mack, 2008, Circulation research.