David E Sanin

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Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing

David E Sanin, Adrian P Mountford, D. E. Sanin, 2015, Parasites & Vectors.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity

Joerg M. Buescher, D. Green, N. Yosef, 2021, Cell.

Polyamine metabolism regulates the T cell epigenome through hypusination

Joerg M. Buescher, D. Green, N. Yosef, 2020, bioRxiv.

Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling

E. Pearce, K. Grzes, K. Klavins, 2022, Mucosal Immunology.

Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity

D. O’Sullivan, Jonathan D. Curtis, E. Pearce, 2020, Cell metabolism.

IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism

David E Sanin, D. E. Sanin, A. Mountford, 2015, The Journal of Immunology.

Predictive framework of macrophage activation

Jonathan D. Curtis, E. Pearce, K. Grzes, 2021, bioRxiv.

Acetate Promotes T Cell Effector Function during Glucose Restriction.

T. Jenuwein, Jonathan D. Curtis, Chih-Hao Chang, 2019, Cell reports.

Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function.

Maxim N. Artyomov, Qiongyu Chen, B. Everts, 2016, Immunity.

Triacylglycerol synthesis enhances macrophage inflammatory function

E. Pearce, E. Pearce, M. Corrado, 2020, Nature Communications.

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

E. Pearce, K. Grzes, M. Corrado, 2019, Cell metabolism.

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

O. Kretz, Qiongyu Chen, S. C. Huang, 2016, Cell.

Metabolic interventions in the immune response to cancer

E. Pearce, Erika L. Pearce, David E Sanin, 2019, Nature Reviews Immunology.

Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection

Jonathan D. Curtis, E. Pearce, E. Pearce, 2022, Science Immunology.

Prostate cancer androgen receptor activity dictates efficacy of Bipolar Androgen Therapy

Elizabeth A. Thompson, J. Luo, Jun Luo, 2022, medRxiv.

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage

Joerg M. Buescher, E. Pearce, B. Kelly, 2019, Nature Immunology.

Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection

David E Sanin, D. E. Sanin, A. Mountford, 2015, International journal for parasitology.

Fever supports CD8+ effector T cell responses by promoting mitochondrial translation

M. Buck, Jonathan D. Curtis, E. Pearce, 2021, Proceedings of the National Academy of Sciences.

Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.

T. Langer, E. Pearce, J. Brüning, 2021, Cell metabolism.

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM).

Jason M. Lynam, I. Fairlamb, J. Moir, 2012, Dalton transactions.

A common framework of monocyte-derived macrophage activation

Jonathan D. Curtis, E. Pearce, K. Grzes, 2022, Science Immunology.

Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive

David E Sanin, D. E. Sanin, A. Mountford, 2015, PLoS pathogens.

Is Linked to Genes CREB-MediatedRegulated by a TLR-Driven IL-10 Production in Macrophages Is

David E Sanin, D. E. Sanin, A. Mountford, 2015 .

An LKB1–mitochondria axis controls TH17 effector function

Joerg M. Buescher, T. Jenuwein, D. O’Sullivan, 2022, Nature.

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

B. Bengsch, Jovana Cupovic, B. Kelly, 2024, Nature communications.

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

Joerg M. Buescher, E. Pearce, K. Grzes, 2023, bioRxiv.

Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2

S. C. Huang, M. Buck, Jonathan D. Curtis, 2018, Immunity.

Mitochondrial DNA in Lung Cancer.

Xiangdong Wang, David E Sanin, D. E. Sanin, 2017, Advances in experimental medicine and biology.

Live Imaging of Mitosomes and Hydrogenosomes by HaloTag Technology

D. Van Tyne, P. Doležal, J. Tachezy, 2012, PloS one.

Sulfur sequestration promotes multicellularity during nutrient limitation

Joerg M. Buescher, Jonathan D. Curtis, T. Becker, 2021, Nature.

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

Joerg M. Buescher, S. Austin, S. Balabanov, 2019, Cell metabolism.

Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF

E. Pearce, K. E. El Kasmi, P. Murray, 2022, Life Science Alliance.

Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters.

E. Pearce, K. Grzes, R. Voll, 2021, Immunity.

Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade

C. Bertozzi, G. Monaco, B. Kasenda, 2021, bioRxiv.

Heterogeneity of exhausted T cells in the tumor microenvironment is linked to patient survival following resection in hepatocellular carcinoma

Yan Lu, Meng-Xin Tian, Wei-ren Liu, 2020, Oncoimmunology.

In macrophages fatty acid oxidation spares glutamate for use in diverse metabolic pathways required for alternative activation

E. Pearce, Lauar B. Monteiro, Erika L. Pearce, 2022, bioRxiv.

Phosphoinositide acyl chain saturation drives CD8^+ effector T cell signaling and function

Joerg M. Buescher, Liang Zhao, Jonathan D. Curtis, 2023, Nature Immunology.