H. Haikala

发表

Troponin C-mediated calcium sensitization by levosimendan accelerates the proportional development of isometric tension.

J. Levijoki, H. Haikala, I. Lindén, 1995, Journal of molecular and cellular cardiology.

Pharmacological mechanisms contributing to the clinical efficacy of levosimendan.

K. Csapo, I. Édes, Z. Papp, 2006, Cardiovascular drug reviews.

Cardiac troponin C as a target protein for a novel calcium sensitizing drug, levosimendan.

J. Levijoki, H. Haikala, I. Lindén, 1995, Journal of molecular and cellular cardiology.

The effects of levosimendan and OR-1896 on isolated hearts, myocyte-sized preparations and phosphodiesterase enzymes of the guinea pig.

I. Édes, P. Kaheinen, J. Levijoki, 2004, European journal of pharmacology.

Effect of Levosimendan on Balance between ATP Production and Consumption in Isolated Perfused Guinea-Pig Heart before Ischemia or after Reperfusion

P. Pollesello, H. Haikala, O. Eriksson, 2004, Journal of cardiovascular pharmacology.

Mechanisms of action of calcium-sensitizing drugs

H. Haikala, I. Lindén, 1995 .

Antiarrhythmic effect and altered calcium sequestration by a cardiotonic agent OR-1259

H. Haikala, 1991 .

Antieosinophilic Activity of Simendans

E. Moilanen, Ritva Tumelius, H. Kankaanranta, 2007, Journal of Pharmacology and Experimental Therapeutics.

Calcium sensitivity enhancers.

P. Pollesello, H. Haikala, 2000, IDrugs : the investigational drugs journal.

Mechanisms of action of calcium-sensitizing drugs.

H. Haikala, I. Lindén, Inge-Britt Lindén, 1995, Journal of cardiovascular pharmacology.

Troponin C–Mediated Calcium Sensitization Induced by Levosimendan Does Not Impair Relaxation

J. Levijoki, H. Haikala, I. Lindén, 1995, Journal of cardiovascular pharmacology.

Effects of Levosimendan and Milrinone on Oxygen Consumption in Isolated Guinea-Pig Heart

P. Kaheinen, J. Levijoki, P. Pollesello, 2004, Journal of cardiovascular pharmacology.

Biochemical properties of OR-1259--a positive inotropic and vasodilatory compound with an antiarrhythmic effect.

A. Raasmaja, H. Haikala, I. Lindén, 1992, Advances in experimental medicine and biology.

Pharmacology of Levosimendan: A New Myofilament Calcium Sensitizer

P. Pentikäinen, P. Pagel, D. Warltier, 1996 .

Positive inotropic effect of levosimendan is correlated to its stereoselective Ca2+-sensitizing effect but not to stereoselective phosphodiesterase inhibition.

A. Borbély, P. Kaheinen, Z. Papp, 2006, Basic & clinical pharmacology & toxicology.

The nicotine-induced changes in striatal dopamine metabolism of mice depend on body temperature

H. Haikala, L. Ahtee, Tuula Karmalahti, 1986, Brain Research.

Effect of neonatal nomifensine exposure on adult behavior and brain monoamines in rats

H. Haikala, L. Ahtee, L. Hilakivi, 2005, Journal of Neural Transmission.

Different changes in striatal dopamine metabolism induced by nicotine in mice kept at different ambient temperatures

H. Haikala, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

Antagonism of the nicotine-induced changes of the striatal dopamine metabolism in mice by mecamylamine and pempidine

H. Haikala, L. Ahtee, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

Two Inotropes With Different Mechanisms of Action: Contractile, PDE-Inhibitory and Direct Myofibrillar Effects of Levosimendan and Enoximone

Szabolcs Szilágyi, István Bak, J. Levijoki, 2005, Journal of cardiovascular pharmacology.

The role of cAMP- and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan.

P. Kaheinen, J. Levijoki, H. Haikala, 1997, Cardiovascular research.

Changes in brain monoamine metabolism during withdrawal from chronic oral self-administration of morphine and in response to a morphine challenge in the withdrawn state.

H. Haikala, L. Ahtee, L. Attila, 1989, The Journal of pharmacology and experimental therapeutics.

Levosimendan Increases Diastolic Coronary Flow in Isolated Guinea-Pig Heart by Opening ATP-Sensitive Potassium Channels

P. Kaheinen, J. Levijoki, P. Pollesello, 2001, Journal of cardiovascular pharmacology.

ORM-3819 promotes cardiac contractility through Ca(2+) sensitization in combination with selective PDE III inhibition, a novel approach to inotropy.

J. Papp, J. Levijoki, Z. Papp, 2016, European journal of pharmacology.

Dual effects of nicotine on neuroleptic-induced changes of striatal dopamine metabolism in mice.

H. Haikala, 1989, Pharmacology & toxicology.

Nicotine antagonizes the effects of reserpine on the striatal metabolism of dopamine, 5-hydroxytryptamine and noradrenaline in hypothermic but not in normothermic mice

H. Haikala, T. Leikola-Pelho, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effects of levosimendan on cardiac remodeling and cardiomyocyte apoptosis in hypertensive Dahl/Rapp rats

E. Vahtola, M. Louhelainen, S. Merasto, 2007, British journal of pharmacology.

Levosimendan, a calcium sensitizer in cardiac muscle, induces relaxation in coronary smooth muscle through calcium desensitization.

R. Paul, H. Haikala, H. Haikala, 1999, The Journal of pharmacology and experimental therapeutics.

Sequential changes of noradrenaline content of vein grafts in rats: Quantitative estimation by high‐performance liquid chromatography using electrochemical detection

T. Waris, J. Hukki, M. Castrèn, 1989, Microsurgery.

Further evidence for the cardiac troponin C mediated calcium sensitization by levosimendan: structure-response and binding analysis with analogs of levosimendan.

A. Annila, I. Kilpeläinen, J. Levijoki, 2000, Journal of molecular and cellular cardiology.

Improved survival with simendan after experimental myocardial infarction in rats.

P. Kaheinen, J. Levijoki, P. Pollesello, 2001, European journal of pharmacology.