M. Signore

发表

Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2.

A. Simeone, E. Puelles, D. Acampora, 2001, Development.

In vivo genetic ablation by Cre‐mediated expression of diphtheria toxin fragment A

J. Martinez-Barbera, N. Greene, A. Copp, 2005, Genesis.

Membrane-anchorage of Cripto protein by glycosylphosphatidylinositol and its distribution during early mouse development

E. Adamson, G. Minchiotti, M. Persico, 2000, Mechanisms of Development.

TCF7L1 is involved in hypothalamo-pituitary axis development in mice and humans

Stephen W. Wilson, S. A. Jayakody, J. Martinez-Barbera, 2016 .

1 TCF 7 L 1 is involved in hypothalamo-pituitary axis development in mice and humans

Stephen W. Wilson, S. A. Jayakody, J. Martinez-Barbera, 2016 .

SOX2 regulates the hypothalamic-pituitary axis at multiple levels.

S. A. Jayakody, J. Martinez-Barbera, M. Dattani, 2012, The Journal of clinical investigation.

Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans

S. A. Jayakody, J. Martinez-Barbera, M. Dattani, 2011, Proceedings of the National Academy of Sciences.

OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation.

A. Simeone, E. Puelles, D. Acampora, 2001, Development.

Otx genes are required for tissue specification in the developing eye.

P. Bovolenta, A. Simeone, D. Acampora, 2001, Development.

Transcription factor 7-like 1 is involved in hypothalamo–pituitary axis development in mice and humans

Stephen W. Wilson, S. A. Jayakody, M. Dattani, 2016, Proceedings of the National Academy of Sciences.

Otx genes in the development and evolution of the vertebrate brain

A. Simeone, D. Acampora, A. Annino, 2001, International Journal of Developmental Neuroscience.

DNMT1 interacts with the developmental transcriptional repressor HESX1

M. Dattani, C. Andoniadou, P. J. Hurd, 2008, Biochimica et biophysica acta.

Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain

M. Dattani, C. Andoniadou, A. Burns, 2007, Development.

Sox2(+) stem/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential.

M. Dattani, T. Jacques, P. L. Le Tissier, 2013, Cell stem cell.

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development.

K. Zaret, R. Bort, M. Signore, 2006, Developmental biology.

Anterior neural plate regionalization in cripto null mutant mouse embryos in the absence of node and primitive streak.

E. Adamson, S. Martinez, D. Echevarrı́a, 2003, Developmental Biology.

P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development

T. Rodríguez, J. Gil, M. Signore, 2018, Nature Communications.

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

N. Greene, A. Copp, D. Gerrelli, 2007, Development.

HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain

Stephen W. Wilson, E. Fuchs, C. Andoniadou, 2011, Development.

Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development.

C. Andoniadou, J. Turner, M. Signore, 2008, Developmental biology.

Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain

W. Wurst, A. Simeone, E. Puelles, 2003, Nature Neuroscience.

Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR.

A. Simeone, D. Acampora, A. Annino, 2001, Development.

Otx genes in evolution: are they involved in instructing the vertebrate brain morphology?

A. Simeone, D. Acampora, A. Annino, 2001, Journal of anatomy.

Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears

Bernd Fritzsch, Massimo Signore, A. Simeone, 2001, Development Genes and Evolution.

Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction.

E. Puelles, M. Dattani, D. Gerrelli, 2011, The Journal of clinical endocrinology and metabolism.

Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism

M. Dattani, D. Gerrelli, C. Andoniadou, 2008, Disease Models & Mechanisms.

Location and Size of Dopaminergic and Serotonergic Cell Populations Are Controlled by the Position of the Midbrain–Hindbrain Organizer

Matthias Oesterheld, Wolfgang Wurst, Massimo Signore, 2003, The Journal of Neuroscience.

Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivity

S. McMahon, K. Futai, F. Denk, 2018, Pain.

Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis

S. McMahon, L. Ramer, M. Ramer, 2015, Acta Neuropathologica Communications.

Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.

R. Rintoul, D. Rassl, G. Doherty, 2023, Cancer cell.

Supporting Online Material Materials and Methods Fig. S1 References Movies S1 to S3

M. Hartman, T. Voyno-Yasenetskaya, P. Flevaris, 2022 .

Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis

S. McMahon, L. Ramer, M. Ramer, 2015, Acta Neuropathologica Communications.

Analysis of mouse models carrying the I 26 T and R 160 C substitutions in the transcriptional repressor HESX 1 as models for septo-optic dysplasia and hypopituitarism

Dianne Gerrelli, Massimo Signore, Juan Pedro Martinez-Barbera, 2022 .