Andrés E Dulcey

发表

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection

Noel Southall, Wei Zheng, Xin Hu, 2015, Journal of medicinal chemistry.

Selective transport of water mediated by porous dendritic dipeptides.

Sergei A Vinogradov, Virgil Percec, S. Vinogradov, 2007, Journal of the American Chemical Society.

Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.

J. Marugan, E. Seto, S. Zanlungo, 2016, Biochimica et biophysica acta.

c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease

Noel Southall, Wei Zheng, J. Marugan, 2022, Frontiers in Cell and Developmental Biology.

Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion

Noel Southall, Zongyi Hu, Xin Hu, 2020, Nature microbiology.

Supramolecular chemistry at the liquid/solid interface probed by scanning tunnelling microscopy

E. W. Meijer, Zhijian Chen, V. Percec, 2006 .

Supramolecular dendritic liquid quasicrystals

V. Percec, G. Ungar, J. Hobbs, 2004, Nature.

The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.

B. Ramakrishnan, G. Griffiths, E. Boeggeman, 2012, Glycobiology.

Identification and Characterization of ML321: a Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity

R. Rodriguiz, W. Wetsel, R. Mach, 2022, bioRxiv.

Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor

M. Ferrer, D. Sibley, Noel Southall, 2014, Molecular Pharmacology.

Discovery, Optimization, and Characterization of Novel D2 Dopamine Receptor Selective Antagonists

Mercedes K. Taylor, M. Ferrer, D. Sibley, 2014, Journal of medicinal chemistry.

SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.

Catherine Z. Chen, M. Ferrer, Noel Southall, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues using glycosyltransferases.

G. Griffiths, P. Qasba, Andrés E. Dulcey, 2011, Tetrahedron.

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus

M. Ferrer, Noel Southall, Xin Hu, 2016, PLoS pathogens.

c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration

J. Marugan, C. Hetz, N. Inestrosa, 2023, Antioxidants.

In vivo characterization of the physicochemical properties of TLR agonist delivery that enhance vaccine immunogenicity

Michael Y. Gerner, Kylie M. Quinn, Janine K. Tom, 2015, Nature Biotechnology.

Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice

J. Marugan, Andrés E Dulcey, A. Chandía-Cristi, 2024, Cell reports.

Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells

M. Ferrer, Noel Southall, A. Jadhav, 2020, Scientific Reports.

Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK

C. Austin, Xin Hu, Wei Zheng, 2017, Autophagy.

Self-assembly of amphiphilic dendritic dipeptides into helical pores

S. D. Hudson, S. Vinogradov, V. Percec, 2004, Nature.

Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.

M. Gottesman, M. Hall, G. Griffiths, 2011, Journal of medicinal chemistry.