Dongguang Qin

Structure-based design, synthesis, evaluation, and crystallographic studies of conformationally constrained Smac mimetics as inhibitors of the X-linked inhibitor of apoptosis protein (XIAP).

Su Qiu, Jianfeng Lu, Chao-Yie Yang, 2008, Journal of medicinal chemistry.

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

Su Qiu, Guoping Wang, Wei Gao, 2006, Journal of medicinal chemistry.

Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

Xueliang Fang, Su Qiu, Xueliang Fang, 2006, Journal of medicinal chemistry.

Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

Xueliang Fang, Su Qiu, Xueliang Fang, 2006, Journal of medicinal chemistry.

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Dajun Yang, Su Qiu, Guoping Wang, 2008, Proceedings of the National Academy of Sciences.

Potent and orally active small-molecule inhibitors of the MDM2-p53 interaction.

Shanghai Yu, Dajun Yang, Su Qiu, 2009, Journal of medicinal chemistry.