I. Hastings

S. Bergström, B. Brabin, S. Massawe, 2007, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Improving Pharmacokinetic-Pharmacodynamic Modeling to Investigate Anti-Infective Chemotherapy with Application to the Current Generation of Antimalarial Drugs

Ian M. Hastings, Katherine Kay, I. Hastings, 2013, PLoS Comput. Biol..

Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp

D. Ménard, I. Felger, E. Hodel, 2019, Antimicrobial Agents and Chemotherapy.

Evaluating artesunate-amodiaquine deployment, efficacy and safety: an in silico pharmacological model

Ki Bae Hong, E. Hodel, I. Hastings, 2019, bioRxiv.

Incorporating Stage Specific Drug Action into Pharmacological 1 Modelling of Antimalarial Drug Treatment 2 3

E. Hodel, I. Hastings, K. Kay, 2016 .

Incorporating Stage-Specific Drug Action into Pharmacological Modeling of Antimalarial Drug Treatment

E. Hodel, I. Hastings, K. Kay, 2016, Antimicrobial Agents and Chemotherapy.

Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness

E. Hodel, I. Hastings, K. Kay, 2015, Antimicrobial Agents and Chemotherapy.

Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling

D. Terlouw, E. Hodel, I. Hastings, 2014, Malaria Journal.

Development, Evaluation, and Application of an In Silico Model for Antimalarial Drug Treatment and Failure

I. Hastings, K. Winter, 2011, Antimicrobial Agents and Chemotherapy.

Leukocytosis as an Alarming Sign for Mortality in Patients Hospitalized in General Wards

N. Beeching, G. Gill, K. Asadollahi, 2011, Iranian journal of medical sciences.

Continued correspondence 'Will ART rollout in Africa drive an epidemic of drug-resistant HIV?'.

S. Khoo, D. Lalloo, I. Hastings, 2007, AIDS.

Will ART rollout in Africa drive an epidemic of drug resistant HIV?

S. Khoo, D. Lalloo, I. Hastings, 2006, AIDS.

Evaluating accuracy of microsatellite markers for classification of recurrent infections during routine monitoring of anti-malarial drug efficacy: A computer modelling approach.

E. Hodel, M. Pluciński, I. Hastings, 2020, Antimicrobial agents and chemotherapy.

Why is sex so frequent?

I. Hastings, 1992, Trends in ecology & evolution.

Population genetics: XYZW as nature's language of love?

I. Hastings, 2006, Heredity.

Should Deep-Sequenced Amplicons Become the New Gold Standard for Analyzing Malaria Drug Clinical Trials?

A. Lerch, I. Felger, E. Hodel, 2021, Antimicrobial agents and chemotherapy.

Should deep-sequenced amplicons become the new gold-standard for analysing malaria drug clinical trials?

A. Lerch, I. Felger, E. Hodel, 2021, bioRxiv.

Incorporating genetic selection into individual‐based models of malaria and other infectious diseases

Raman Sharma, I. Hastings, K. Kay, 2020, Evolutionary applications.

The geographical distribution of allele polymorphisms of Plasmodium vivax in different regions of Thailand.

A. Craig, I. Hastings, U. Lek-Uthai, 2012, Journal of the Medical Association of Thailand = Chotmaihet thangphaet.

The Plasmodium falciparum var gene switching rate, switching mechanism and patterns of parasite recrudescence described by mathematical modelling

M. Gatton, A. Saul, I. Hastings, 2002, Parasitology.

Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance

Thomas A. Smith, B. Genton, J. Marfurt, 2010, Malaria Journal.

Mapping of putative QTL influencing body weight on the X chromosome in mice.

W. G. Hill, P. Keightley, I. Hastings, 1994 .

Reproductive compensation and human genetic disease.

I. Hastings, 2001, Genetical research.

The impact of endemic and epidemic malaria on the risk of stillbirth in two areas of Tanzania with different malaria transmission patterns

B. Brabin, U. U. Wort, I. Hastings, 2006, Malaria Journal.

Markov chain Monte Carlo and expectation maximization approaches for estimation of haplotype frequencies for multiply infected human blood samples

G. Ken-Dror, I. Hastings, 2016, Malaria Journal.

The role of windows of selection and windows of dominance in the evolution of insecticide resistance in human disease vectors

R. Lees, A. South, I. Hastings, 2019, Evolutionary applications.

Insecticide resistance evolution with mixtures and sequences: a model-based explanation

Andy South, Ian M Hastings, A. South, 2018, Malaria Journal.

The role of growth hormone in lines of mice divergently selected on body weight.

W. G. Hill, I. Hastings, L. H. Bootland, 1993, Genetical research.

Impaired fitness of drug-resistant malaria parasites: evidence and implication on drug-deployment policies

H. Babiker, I. Hastings, G. Swedberg, 2009, Expert review of anti-infective therapy.

The anatomy of a malaria disaster: drug policy choice and mortality in African children.

P. Bloland, E. Korenromp, I. Hastings, 2007, The Lancet. Infectious diseases.

Gametocytocidal activity in antimalarial drugs speeds the spread of drug resistance

I. Hastings, 2006, Tropical medicine & international health : TM & IH.

Tolerance is the key to understanding antimalarial drug resistance.

W. Watkins, I. Hastings, 2006, Trends in parasitology.

Complex dynamics and stability of resistance to antimalarial drugs

I. Hastings, Ian M. Hastings, 2006, Parasitology.

The search for effective and sustainable treatments for Plasmodium falciparum malaria in Africa: a model of the selection of resistance by antifolate drugs and their combinations.

W. Watkins, C. Sibley, I. Hastings, 2005, The American journal of tropical medicine and hygiene.

The impact of antimalarial drug resistance mutations on parasite fitness, and its implications for the evolution of resistance.

Ian M Hastings, M. Donnelly, Martin J Donnelly, 2005, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

The origins of antimalarial drug resistance.

I. Hastings, 2004, Trends in parasitology.

How artemisinin-containing combination therapies slow the spread of antimalarial drug resistance.

I. Hastings, 2011, Trends in parasitology.

Quantifying the evolution and impact of antimalarial drug resistance: drug use, spread of resistance, and drug failure over a 12-year period in Papua New Guinea.

Thomas A. Smith, A. Schapira, B. Genton, 2010, The Journal of infectious diseases.

The genetic polymorphism of Plasmodium vivax genes in endemic regions of Thailand.

A. Craig, I. Hastings, U. Lek-Uthai, 2011, Asian Pacific journal of tropical medicine.

Incorporating genetic selection into individual-based models (IBMs) of malaria and other infectious diseases

Ian M. Hastings, Raman Sharma, Raman Sharma, 2019, bioRxiv.

Field, genetic, and modeling approaches show strong positive selection acting upon an insecticide resistance mutation in Anopheles gambiae s.s.

J. Pinto, A. Lynd, M. Donnelly, 2010, Molecular biology and evolution.

Response to: The puzzling links between malaria transmission level and drug resistance

I. Hastings, 2003 .

Malaria control and the evolution of drug resistance: an intriguing link.

I. Hastings, 2003, Trends in parasitology.

WHO antimalarial trial guidelines: good science, bad news?

I. Felger, I. Hastings, 2022, Trends in parasitology.

Modelling a predictable disaster: the rise and spread of drug-resistantmalaria.

U. d’Alessandro, I. Hastings, Ian M. Hastings, 2000, Parasitology today.

The evolution of multiple drug resistance in malaria parasites.

M. Mackinnon, I. Hastings, Ian M. Hastings, 1998, Transactions of the Royal Society of Tropical Medicine and Hygiene.

MalHaploFreq: A computer programme for estimating malaria haplotype frequencies from blood samples

Thomas A. Smith, I. Hastings, 2008, Malaria Journal.

A Computer Modelling Approach To Evaluate the Accuracy of Microsatellite Markers for Classification of Recurrent Infections during Routine Monitoring of Antimalarial Drug Efficacy

E. Hodel, M. Pluciński, I. Hastings, 2020, Antimicrobial Agents and Chemotherapy.

The influence of biological, epidemiological, and treatment factors on the establishment and spread of drug-resistant Plasmodium falciparum

M. Penny, M. Golumbeanu, S. Kelly, 2022, medRxiv.

Malaria and Irrigated Crops, Accra, Ghana

M. Donnelly, P. McCall, M. Wilson, 2005, Emerging infectious diseases.

Malaria and urbanization in sub-Saharan Africa

C. Lengeler, U. d’Alessandro, J. Trape, 2005, Malaria Journal.

Mutation and selection within the individual

Ian M. Hastings, Sarah P. Otto, S. Otto, 2004, Genetica.

Analysis of lines of mice selected on fat content. 4. Correlated responses in growth and reproduction.

W. G. Hill, I. Hastings, J. Yang, 1991, Genetical research.

Prenatal growth in lines of mice selected for body weight

W. G. Hill, L. Bünger, I. Hastings, 1996 .

Population genetic aspects of deleterious cytoplasmic genomes and their effect on the evolution of sexual reproduction.

I. Hastings, 1992, Genetical research.

Effects of thyroid hormone deficiency on mice selected for increased and decreased body weight and fatness.

W. G. Hill, L. Bünger, H. Wallace, 1998, Genetical research.

Behavioural changes as a correlated response to selection.

I. Hastings, I. S. Holmes, 1995, Genetical research.

The genetic basis of response in mouse lines divergently selected for body weight or fat content. I. The relative contributions of autosomal and sex-linked genes.

R. Veerkamp, I. Hastings, 1993, Genetical research.

Estimation of changes in genetic parameters in selected lines of mice using REML with an animal model. 2. Body weight, body composition and litter size

W. G. Hill, R. Thompson, W G Hill, 1992, Heredity.

Analysis of lines of mice selected for fat content. 2. Correlated responses in the activities of enzymes involved in lipogenesis.

W. G. Hill, I. Hastings, 1990, Genetical research.

A note on the effect of different selection criteria on carcass composition in mice

W. G. Hill, I. Hastings, 1989 .

Genetic and biochemical analyses of growth

Ian M. Hastings, I. Hastings, 1989 .

Effects of selection on food intake in the adult mouse.

L Bünger, W. G. Hill, L. Bünger, 1997, Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie.

Mathematical models of human african trypanosomiasis epidemiology.

M. Keeling, N. Chitnis, S. Torr, 2015, Advances in parasitology.

Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

S. Torr, M. Lehane, P. Solano, 2015, PLoS neglected tropical diseases.

THE IMPORTANCE OF MOSQUITO BEHAVIOURAL ADAPTATIONS TO MALARIA CONTROL IN AFRICA

John M. Marshall, Nakul Chitnis, Michelle L Gatton, 2013, Evolution; international journal of organic evolution.

Entomological indices of malaria transmission in Chikhwawa district, Southern Malawi

M. Molyneux, P. McCall, T. Mzilahowa, 2012, Malaria Journal.

Modelling parasite drug resistance: lessons for management and control strategies

I. Hastings, 2001, Tropical medicine & international health : TM & IH.

Germline selection: population genetic aspects of the sexual/asexual life cycle.

I. Hastings, Ian M. Hastings, 1991, Genetics.

Models of human genetic disease: how biased are the standard formulae?

I. Hastings, 2000, Genetical research.

Challenges in Estimating Insecticide Selection Pressures from Mosquito Field Data

I. Hastings, W. Black, Susana Barbosa, 2011, PLoS neglected tropical diseases.

The emergence of drug-resistant malaria

M. Mackinnon, I. Hastings, 1998, Parasitology.

Sex, strains and virulence.

I. Hastings, B. Wedgwood-Oppenheim, 1997, Parasitology today.

Genetics and malaria--more questions than answers.

A. Pain, A. Craig, I. Hastings, 2001, Trends in parasitology.

Potential germline competition in animals and its evolutionary implications.

I. Hastings, Ian M. Hastings, 1989, Genetics.

PfCRT and the trans‐vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX

Ruth H. Hughes, D. Fidock, P. Stocks, 2006, Molecular microbiology.

Selfish DNA as a method of pest control.

I. Hastings, 1994, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Evaluating rotations as a strategy to delay the evolution of insecticide resistance in vectors of human diseases

A. South, I. Hastings, S. Jones, 2022, bioRxiv.

A Two-Locus Model of the Evolution of Insecticide Resistance to Inform and Optimise Public Health Insecticide Deployment Strategies

Bethany Levick, Andy South, Ian M. Hastings, 2017, PLoS Comput. Biol..

American Society of Tropical Medicine and Hygiene--49th annual meeting.

I. Hastings, 2001, IDrugs : the investigational drugs journal.

Laboratory risk factors for hospital mortality in acutely admitted patients.

N. Beeching, G. Gill, G. Gill, 2007, QJM : monthly journal of the Association of Physicians.

The population genetics of alleles affecting enzyme activity.

I. Hastings, 1992, Journal of theoretical biology.

Impact of El Niño and malaria on birthweight in two areas of Tanzania with different malaria transmission patterns.

B. Brabin, T. Mutabingwa, U. U. Wort, 2004, International journal of epidemiology.

Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance.

François Nosten, Ian M Hastings, F. Nosten, 2007, The Lancet. Infectious diseases.

Can mutation and selection explain virulence in human P. falciparum infections?

Ian M Hastings, A. Saul, I. Hastings, 2004, Malaria Journal.

ogaraK: a population genetics simulator for malaria

Ian M. Hastings, Tiago Antao, T. Antão, 2011, Bioinform..

Title : Improving the role and contribution of pharmacokinetic analyses in antimalarial drug 1 clinical trials 2 3 4 Running Title : Pharmacokinetics in antimalarial drug trials

E. Hodel, I. Hastings, K. Kay, 2014 .

Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission

N. Chitnis, I. Hastings, K. Kay, 2018, Parasites & Vectors.

No room for complacency on drug resistance in Africa

Ian M. Hastings, David G. Lalloo, Saye H. Khoo, 2006, Nature.

Prediction of hospital mortality from admission laboratory data and patient age: A simple model

Ian M Hastings, N. Beeching, K. Asadollahi, 2011, Emergency medicine Australasia : EMA.

Improving the Role and Contribution of Pharmacokinetic Analyses in Antimalarial Drug Clinical Trials

E. Hodel, I. Hastings, K. Kay, 2014, Antimicrobial Agents and Chemotherapy.

Molecular markers as indicators of antimalarial drug failure rates

I. Hastings, 2007, Tropical medicine & international health : TM & IH.

Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria.

N. Speybroeck, E. van Marck, U. d’Alessandro, 2003, International journal for parasitology.

A comparison of methods to detect and quantify the markers of antimalarial drug resistance.

C. Nsanzabana, Tom A Smith, I. Hastings, 2010, The American journal of tropical medicine and hygiene.

PCR correction strategies for malaria drug trials: updates and clarifications.

G. Snounou, I. Felger, H. Beck, 2019, The Lancet. Infectious diseases.

Population genetics and the detection of immunogenic and drug-resistant loci in Plasmodium

I. Hastings, 1996, Parasitology.

The Importance of Scientific Debate in the Identification, Containment, and Control of Artemisinin Resistance.

E. Hodel, I. Hastings, K. Kay, 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Manifestations of sexual selection may depend on the genetic basis of sex determination

I. Hastings, 1994, Proceedings of the Royal Society of London. Series B: Biological Sciences.

The importance of modelling the spread of insecticide resistance in a heterogeneous environment: the example of adding synergists to bed nets

I. Hastings, Susana Barbosa, 2012, Malaria Journal.

Optimal Treatments for Severe Malaria and the Threat Posed by Artemisinin Resistance

Raman Sharma, E. Hodel, I. Hastings, 2018, The Journal of infectious diseases.

The spread of antimalarial drug resistance: A mathematical model with practical implications for ACT drug policies

N. Day, N. White, S. Yeung, 2008 .

Seasonal malaria chemoprevention and the spread of Plasmodium falciparum quintuple mutant parasites resistant to sulfadoxine-pyrimethamine: a modelling study

M. Penny, S. Kelly, I. Hastings, 2023, medRxiv.

The impact of Fisher’s Reproductive Compensation on raising equilibrium frequencies of semi-dominant, non-lethal mutations under mutation/selection balance

I. Hastings, 2021, bioRxiv.

A lifetime perspective on foraging and mortality.

I. Gordon, I. Kyriazakis, J. Yearsley, 2002, Journal of theoretical biology.

The genetic basis of response in mouse lines divergently selected for body weight or fat content. II. The contribution of genes with a large effect.

R. Veerkamp, C. Haley, S. Knott, 1993, Genetical research.

Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness

E. Hodel, I. Hastings, Katherine Kay, 2015, Antimicrobial Agents and Chemotherapy.

Analysing malaria drug trials on a per‐individual or per‐clone basis: a comparison of methods

T. Jaki, I. Hastings, K. Winter, 2013, Statistics in medicine.

Prediction of hospital mortality from admission laboratory data and patient age: A simple model

N. Beeching, K. Asadollahi, I. Hastings, 2011, Emergency Medicine Australasia.

The epidemiology of malaria in adults in a rural area of southern Mozambique

Andrew P. Morse, C. Menéndez, M. Dgedge, 2007, Malaria Journal.

Insecticide resistance management strategies for public health control of mosquitoes exhibiting polygenic resistance: A comparison of sequences, rotations, and mixtures

D. Weetman, I. Hastings, N. Hobbs, 2022, bioRxiv.

How best to co-deploy insecticides to minimise selection for resistance

A. South, J. Richardson, G. Small, 2023, bioRxiv.

Male-specific insecticide resistance and mosquito transgene dispersal.

S. Sinkins, I. Hastings, 2004, Trends in parasitology.