Stefanie König

发表

Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum.

C. Gatz, I. Feussner, K. Feussner, 2014, The New phytologist.

Indirubin core structure of glycogen synthase kinase-3 inhibitors as novel chemotype for intervention with 5-lipoxygenase.

O. Werz, A. Skaltsounis, N. Gaboriaud-Kolar, 2014, Journal of medicinal chemistry.

The indirubin derivative 6-bromoindirubin-3'-glycerol-oxime ether (6BIGOE) potently modulates inflammatory cytokine and prostaglandin release from human monocytes through GSK-3 interference.

O. Werz, A. Skaltsounis, D. Fischer, 2020, Biochemical pharmacology.

Functional Characterization of CYP94-Genes and Identification of a Novel Jasmonate Catabolite in Flowers

I. Feussner, K. Feussner, Florian Brodhun, 2016, PloS one.

Arabidopsis mutants of sphingolipid fatty acid α-hydroxylases accumulate ceramides and salicylates.

Tim Iven, I. Feussner, K. Feussner, 2012, The New phytologist.

Triterpene Acids from Frankincense and Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G

O. Werz, A. Koeberle, D. Fischer, 2018, Molecules.

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

Sandra K. Wittmann, G. Scriba, O. Werz, 2017, Scientific Reports.

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase

S. Lorkowski, O. Werz, D. Schuster, 2018, Nature Communications.

Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase.

O. Werz, J. Haeggström, E. Proschak, 2019, Cell chemical biology.

Comparative Genome Annotation.

M. Stanke, Stefanie König, Lars Romoth, 2018, Methods in molecular biology.

Myxochelin‐Inspired 5‐Lipoxygenase Inhibitors: Synthesis and Biological Evaluation

O. Werz, M. Nett, S. Pace, 2017, ChemMedChem.

Expanding the Rubterolone Family: Intrinsic Reactivity and Directed Diversification of PKS-derived Pyrans.

C. Steinbeck, O. Werz, M. Poulsen, 2018, Chemistry.

Transcriptional activation and production of tryptophan-derived secondary metabolites in arabidopsis roots contributes to the defense against the fungal vascular pathogen Verticillium longisporum.

G. Braus, Tim Iven, I. Feussner, 2012, Molecular plant.

Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159.

O. Werz, D. Steinhilber, M. Karas, 2019, Cell chemical biology.

Melleolides impact fungal translation via elongation factor 2.

O. Werz, D. Hoffmeister, C. Hertweck, 2019, Organic & biomolecular chemistry.

Disruption of Arabidopsis neutral ceramidases 1 and 2 results in specific sphingolipid imbalances triggering different phytohormone-dependent plant cell death programs.

I. Feussner, C. Herrfurth, A. Zienkiewicz, 2019, The New phytologist.

PEP7 acts as a peptide ligand for the receptor kinase SIRK1 to regulate aquaporin-mediated water influx and lateral root growth.

K. Harter, W. Schulze, X. Wu, 2022, Molecular plant.

Bioactivity and Mode of Action of Bacterial Tetramic Acids.

O. Werz, Pierre Stallforth, S. Pace, 2019, ACS chemical biology.

Phenylpropanoids and long chain fatty acid derivatives in the interaction of Arabidopsis thaliana and Verticillium longisporum

Stefanie König, 2012 .

Structure and biosynthetic assembly of gulmirecins, macrolide antibiotics from the predatory bacterium Pyxidicoccus fallax.

O. Werz, M. Nett, H. Dahse, 2014, Chemistry.

Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone.

O. Werz, Katja Wiechmann, A. Svatoš, 2017, Cell chemical biology.

Myxochelins target human 5-lipoxygenase.

O. Werz, M. Nett, H. Dahse, 2015, Journal of Natural Products.

Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5‐Lipoxygenase Inhibitors

O. Werz, M. Nett, G. König, 2015, Chembiochem : a European journal of chemical biology.

Phytochemical Profile of the Aerial Parts of Sedum sediforme and Anti-inflammatory Activity of Myricitrin

O. Werz, H. Stuppner, B. Waltenberger, 2015, Natural product communications.

Melleolides induce rapid cell death in human primary monocytes and cancer cells.

O. Werz, Katja Wiechmann, D. Hoffmeister, 2014, Bioorganic & medicinal chemistry.

Sphingolipid-Induced Programmed Cell Death is a Salicylic Acid and EDS1-Dependent Phenotype in Arabidopsis Fatty Acid Hydroxylase (Fah1, Fah2) and Ceramide Synthase (Loh2) Triple Mutants

I. Feussner, C. Herrfurth, K. Zienkiewicz, 2021, bioRxiv.

Protective Effect of Casperome®, an Orally Bioavailable Frankincense Extract, on Lipopolysaccharide- Induced Systemic Inflammation in Mice

O. Werz, A. Koeberle, A. Lupp, 2018, Front. Pharmacol..

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase

S. Lorkowski, O. Werz, D. Schuster, 2018, Nature Communications.

Cytotoxic effects and degradation products of three mycotoxins: alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in liver hepatocellular carcinoma cells.

C. Juan, A. Juan-García, M. Ruiz, 2015, Toxicology letters.

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.

O. Werz, D. Schuster, H. Stuppner, 2018, European journal of medicinal chemistry.

Simultaneous gene finding in multiple genomes

Mario Stanke, Lizzy Gerischer, Stefanie König, 2016, Bioinform..

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

Sandra K. Wittmann, G. Scriba, O. Werz, 2017, Scientific Reports.

Mitochondrial Chaperonin HSP 60 Is the Apoptosis-Related Target for Myrtucommulone Graphical Abstract Highlights

O. Werz, Katja Wiechmann, N. Wielsch, 2017 .

Novel thiazolopyridine derivatives of diflapolin as dual sEH/FLAP inhibitors with improved solubility.

O. Werz, D. Schuster, V. Temml, 2023, Bioorganic chemistry.

Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase

O. Werz, J. Haeggström, B. Samuelsson, 2023, International journal of molecular sciences.

PEP7 is a ligand for receptor kinase SIRK1 to regulate aquaporins and root growth

K. Harter, W. Schulze, X. Wu, 2022, bioRxiv.

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.

O. Werz, D. Schuster, H. Stuppner, 2018, European journal of medicinal chemistry.