A. Arighi

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Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

Veronica Redaelli, Sebastien Ourselin, Martina Bocchetta, 2019, Brain : a journal of neurology.

MiRNA Profiling in Plasma Neural-Derived Small Extracellular Vesicles from Patients with Alzheimer’s Disease

D. Galimberti, C. Fenoglio, E. Scarpini, 2020, Cells.

The Brain is Hypothermic in Patients with Mitochondrial Diseases

N. Bresolin, G. Comi, R. del Bo, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Structural and metabolic cerebral alterations between elderly bipolar disorder and behavioural variant frontotemporal dementia: A combined MRI-PET study

P. Brambilla, A. Altamura, D. Galimberti, 2018, The Australian and New Zealand journal of psychiatry.

A Critical Review on Structural Neuroimaging Studies in BD: a Transdiagnostic Perspective from Psychosis to Fronto-Temporal Dementia

M. Bellani, P. Brambilla, D. Galimberti, 2020, Current Behavioral Neuroscience Reports.

Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2019, The Lancet Neurology.

White Matter Hyperintensities Are No Major Confounder for Alzheimer’s Disease Cerebrospinal Fluid Biomarkers

Linda J. C. van Waalwijk van Doorn, G. Frisoni, H. Soininen, 2020, Journal of Alzheimer's disease : JAD.

PRNP P39L Variant is a Rare Cause of Frontotemporal Dementia in Italian Population.

D. Mari, S. Sorbi, C. Mariani, 2016, Journal of Alzheimer's disease : JAD.

Brain temperature in multiple sclerosis

N. Bresolin, D. Galimberti, E. Scarpini, 2014, Multiple sclerosis.

Low CSF β-amyloid levels predict early regional grey matter atrophy in multiple sclerosis.

D. Galimberti, C. Fenoglio, E. Scarpini, 2019, Multiple sclerosis and related disorders.

Amyloid PET as a marker of normal-appearing white matter early damage in multiple sclerosis: correlation with CSF β-amyloid levels and brain volumes

M. Bozzali, D. Galimberti, C. Fenoglio, 2018, European Journal of Nuclear Medicine and Molecular Imaging.

PINK1 parkinsonism and Parkinson disease: distinguishable brain mitochondrial function and metabolomics.

N. Bresolin, G. Marotta, M. Rango, 2013, Mitochondrion.

A novel MAPT mutation associated with the clinical phenotype of progressive nonfluent aphasia

N. Bresolin, S. Cappa, D. Galimberti, 2011, Alzheimer's & Dementia.

Profiling of Ubiquitination Pathway Genes in Peripheral Cells from Patients with Frontotemporal Dementia due to C9ORF72 and GRN Mutations

D. Galimberti, C. Fenoglio, E. Scarpini, 2015, International journal of molecular sciences.

White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2019, NeuroImage: Clinical.

Lactate detection in the brain of growth-restricted fetuses with magnetic resonance spectroscopy.

N. Bresolin, G. Pardi, I. Cetin, 2011, American journal of obstetrics and gynecology.

Magnetic resonance spectroscopy in Parkinson's disease and parkinsonian syndromes.

N. Bresolin, G. Nappi, E. Martignoni, 2007, Functional neurology.

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes.

Linda J. C. van Waalwijk van Doorn, K. Blennow, J. Molinuevo, 2017, Journal of Alzheimer's disease : JAD.

Patient-Reported Symptoms and Sequelae 12 Months After COVID-19 in Hospitalized Adults: A Multicenter Long-Term Follow-Up Study

M. Mantero, P. Brambilla, P. Lampertico, 2022, Frontiers in Medicine.

Plasma Screening for Progranulin Mutations in Patients with Progressive Supranuclear Palsy and Corticobasal Syndromes.

D. Galimberti, C. Fenoglio, E. Scarpini, 2016, Journal of Alzheimer's disease : JAD.

Accuracy of the clinical diagnosis of dementia with Lewy bodies (DLB) among the Italian Dementia Centers: a study by the Italian DLB study group (DLB-SINdem)

D. Perani, C. Babiloni, M. Bozzali, 2022, Neurological Sciences.

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study

D. Galimberti, M. Bocchetta, J. Rohrer, 2018, Neurobiology of Aging.

CSF β-amyloid and white matter damage: a new perspective on Alzheimer’s disease

Giovanni Giulietti, Marco Bozzali, Alberto Calvi, 2017, Journal of Neurology, Neurosurgery, and Psychiatry.

Inflammatory molecules in Frontotemporal Dementia: Cerebrospinal fluid signature of progranulin mutation carriers

D. Galimberti, C. Fenoglio, E. Scarpini, 2015, Brain, Behavior, and Immunity.

Aquaporin-4 cerebrospinal fluid levels are higher in neurodegenerative dementia: looking at glymphatic system dysregulation

F. Turkheimer, D. Galimberti, C. Fenoglio, 2022, Alzheimer's Research & Therapy.

Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data

S. Cappa, S. Weintraub, S. Sorbi, 2022, Alzheimer's Research & Therapy.

miRNA Expression Is Increased in Serum from Patients with Semantic Variant Primary Progressive Aphasia

D. Galimberti, C. Fenoglio, M. Serpente, 2022, International journal of molecular sciences.

Behavioral Variant of Frontotemporal Dementia and Homicide in a Historical Case

G. Sartori, S. Zago, C. Scarpazza, 2021, The Journal of the American Academy of Psychiatry and the Law.

Early onset behavioral variant frontotemporal dementia due to the C9ORF72 hexanucleotide repeat expansion: psychiatric clinical presentations.

N. Bresolin, D. Galimberti, C. Fenoglio, 2012, Journal of Alzheimer's disease : JAD.

Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2022, Journal of Neuroinflammation.

Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations

Jennifer M. Nicholas, P. Thompson, R. Keren, 2022, Journal of Neurology.

The CBI‐R detects early behavioural impairment in genetic frontotemporal dementia

Nick C Fox, M. Freedman, S. Ourselin, 2022, Annals of clinical and translational neurology.

The novel GRN g.1159_1160delTG mutation is associated with behavioral variant frontotemporal dementia.

D. Galimberti, C. Fenoglio, E. Scarpini, 2015, Journal of Alzheimer's disease : JAD.

The Role of Glymphatic System in Alzheimer’s and Parkinson’s Disease Pathogenesis

D. Galimberti, M. Serpente, M. D’Anca, 2022, Biomedicines.

Evidence of CNS β-amyloid deposition in Nasu-Hakola disease due to the TREM2 Q33X mutation

D. Galimberti, C. Fenoglio, E. Scarpini, 2017, Neurology.

Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Jennifer M. Nicholas, Sheng-Yang M. Goh, M. Freedman, 2022, Nature Medicine.

Monozygotic Twins with Frontotemporal Dementia Due To Thr272fs GRN Mutation Discordant for Age At Onset.

D. Galimberti, C. Fenoglio, E. Scarpini, 2019, Journal of Alzheimer's disease : JAD.

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy – Related In ﬂ ammation A Multicenter Prospective Longitudinal Cohort Study

R. Marconi, G. Basso, D. Inzitari, 2022 .

Diogenes syndrome in dementia: a case report

P. Brambilla, D. Galimberti, E. Scarpini, 2021, BJPsych Open.

Ischaemic Stroke of the “Hand-Knob” Area Due to Paradoxical Cerebral Air Embolism after Central Venous Catheterization—A Doubly Rare Occurrence: A Case Report and an Overview of Pathophysiology, Diagnosis, and Treatment

S. Carugo, T. Lucchi, A. Arighi, 2022, Brain sciences.

Myoinositol content in the human brain is modified by transcranial direct current stimulation in a matter of minutes: A 1H‐MRS study

A. Priori, S. Marceglia, F. Cogiamanian, 2008, Magnetic resonance in medicine.

Partial recovery after severe immune reconstitution inflammatory syndrome in a multiple sclerosis patient with progressive multifocal leukoencephalopathy.

G. Comi, D. Galimberti, E. Scarpini, 2014, Immunotherapy.

Cerebrospinal fluid glutamate changes in functional movement disorders

A. Priori, D. Galimberti, T. Bocci, 2020, NPJ Parkinson's disease.

QEEG abnormalities in cognitively unimpaired patients with delirium

C. Babiloni, M. Onofrj, L. Bonanni, 2022, Journal of Neurology, Neurosurgery, and Psychiatry.

A 66-year-old patient with vanishing white matter disease due to the p.Ala87Val EIF2B3 mutation

N. Bresolin, D. Galimberti, E. Scarpini, 2012, Neurology.

A Novel Automated Chemiluminescence Method for Detecting Cerebrospinal Fluid Amyloid-Beta 1-42 and 1-40, Total Tau and Phosphorylated-Tau: Implications for Improving Diagnostic Performance in Alzheimer’s Disease

D. Galimberti, C. Fenoglio, E. Scarpini, 2022, Biomedicines.

CIRCULATING AND INTRATHECAL MIRNAS AS POTENTIAL BIOMARKERS FOR ALZHEIMER'S DISEASE

D. Galimberti, C. Fenoglio, E. Scarpini, 2014, Alzheimer's & Dementia.

Quantitative susceptibility mapping of the normal-appearing white matter as a potential new marker of disability progression in multiple sclerosis

A. Bianchi, D. Galimberti, C. Fenoglio, 2022, European Radiology.

Oligomeric α-synuclein and tau aggregates in NDEVs differentiate Parkinson's disease from atypical parkinsonisms

C. Fenoglio, F. Guerini, C. Agliardi, 2023, Neurobiology of Disease.

The Neuroanatomy of Somatoform Disorders: A Magnetic Resonance Imaging Study.

P. Brambilla, A. Altamura, D. Galimberti, 2019, Psychosomatics.

CSF β-amyloid predicts prognosis in patients with multiple sclerosis

M. Bozzali, D. Galimberti, C. Fenoglio, 2018, Multiple sclerosis.

Usefulness of Multi-Parametric MRI for the Investigation of Posterior Cortical Atrophy

N. Bresolin, M. Bozzali, D. Galimberti, 2015, PloS one.

Behavioral and Neurophysiological Effects of Transcranial Direct Current Stimulation (tDCS) in Fronto-Temporal Dementia

A. Priori, S. Marceglia, M. Vergari, 2018, Front. Behav. Neurosci..

Biomarkers and phenotypic expression in Alzheimer’s disease: exploring the contribution of frailty in the Alzheimer’s Disease Neuroimaging Initiative

M. Cesari, I. Arisi, D. Galimberti, 2020, GeroScience.

Plasma microglial-derived extracellular vesicles are increased in frail patients with Mild Cognitive Impairment and exert a neurotoxic effect

Arosio, D. Galimberti, C. Fenoglio, 2023, GeroScience.

Enzyme Activity in Frozen Vegetables

M. Joslyn, A. Arighi, G. L. March, 1936 .

Evidence of retinal anterograde neurodegeneration in the very early stages of multiple sclerosis: a longitudinal OCT study

D. Galimberti, C. Fenoglio, E. Scarpini, 2020, Neurological Sciences.

Circulating Non-Coding RNA Levels Are Altered in Autosomal Dominant Frontotemporal Dementia

D. Galimberti, C. Fenoglio, E. Scarpini, 2022, International journal of molecular sciences.

Role of aquaporins in hydrocephalus: what do we know and where do we stand? A systematic review

C. Giussani, E. Sganzerla, Camilla de Laurentis, 2020, Journal of Neurology.

Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study

Jennifer M. Nicholas, M. Freedman, N. Fox, 2021, Alzheimer's & dementia.

Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2020, Cortex.

Brain temperature: What do we know?

N. Bresolin, M. Rango, A. Arighi, 2012, Neuroreport.

Increased brain temperature in Parkinson’s disease

N. Bresolin, M. Rango, A. Arighi, 2012, Neuroreport.

A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2021, Brain : a journal of neurology.

Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis

Veronica Redaelli, Sebastien Ourselin, Martina Bocchetta, 2015, The Lancet Neurology.

Hallucinations in Neurological Disorders

A. Fonzo, E. Monfrini, A. Arighi, 2018 .

Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2019, Neurobiology of Aging.

Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales

Nick C Fox, M. Freedman, S. Ourselin, 2018, Alzheimer's research & therapy.

Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales

Jennifer M. Nicholas, M. Freedman, R. Keren, 2022, Journal of Neurology.

ID 303 – Transcranial direct current stimulation (tDCS) in patients with frontotemporal dementia

A. Priori, M. Vergari, R. Ferrucci, 2016, Clinical Neurophysiology.

Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study

M. Freedman, J. Dukart, R. Keren, 2023, Neurobiology of Disease.

Autosomal Dominant Frontotemporal Lobar Degeneration Due to the C9ORF72 Hexanucleotide Repeat Expansion: Late-Onset Psychotic Clinical Presentation

G. Comi, S. Cappa, M. Filippi, 2013, Biological Psychiatry.

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2020, NeuroImage: Clinical.

Alzheimer’s Disease Diagnosis: Discrepancy between Clinical, Neuroimaging, and Cerebrospinal Fluid Biomarkers Criteria in an Italian Cohort of Geriatric Outpatients: A Retrospective Cross-sectional Study

D. Mari, E. Scarpini, M. Marcucci, 2017, Front. Med..

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Nick C Fox, Keith A. Johnson, Raymond Scott Turner, 2017, Nature Communications.

Parieto-occipital sulcus widening differentiates posterior cortical atrophy from typical Alzheimer disease

D. Galimberti, E. Scarpini, F. Triulzi, 2020, NeuroImage: Clinical.

Facing the digital divide into a dementia clinic during COVID-19 pandemic: caregiver age matters

D. Galimberti, E. Scarpini, M. D. De Riz, 2021, Neurological Sciences.

Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative cohort

J. E. Iglesias, Jennifer M. Nicholas, M. Freedman, 2023, Brain communications.

Differential early subcortical involvement in genetic FTD within the GENFI cohort

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2021, NeuroImage: Clinical.

Central hyperthermia, brain hyperthermia and low hypothalamus temperature

N. Bresolin, M. Rango, A. Arighi, 2012, Clinical Autonomic Research.

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy–Related Inflammation

R. Marconi, R. Carare, G. Basso, 2021, Neurology.

The loss of macular ganglion cells begins from the early stages of disease and correlates with brain atrophy in multiple sclerosis patients

Francesco Viola, Eleonora Benatti, Fabio Triulzi, 2019, Multiple sclerosis.

Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia.

P. Mazzanti, C. Mussi, D. Cucinotta, 2020, Journal of the American Medical Directors Association.

Analysis of C9orf72 Intermediate Alleles in a Retrospective Cohort of Neurological Patients: Risk Factors for Alzheimer's Disease?

D. Galimberti, C. Fenoglio, E. Scarpini, 2021, Journal of Alzheimer's disease : JAD.

Circulating miRNAs as potential biomarkers in Alzheimer's disease.

D. Galimberti, C. Fenoglio, E. Scarpini, 2014, Journal of Alzheimer's disease : JAD.

Banks of the Superior Temporal Sulcus in Alzheimer's Disease: A Pilot Quantitative Susceptibility Mapping Study.

D. Galimberti, C. Fenoglio, E. Scarpini, 2023, Journal of Alzheimer's disease : JAD.

Late‐onset presentation and phenotypic heterogeneity of the rare R377W PSEN1 mutation

Y. Pijnenburg, D. Galimberti, C. Fenoglio, 2020, European journal of neurology.

Inflammatory expression profile in peripheral blood mononuclear cells from patients with Nasu‐Hakola Disease

D. Galimberti, C. Fenoglio, L. Piccio, 2019, Cytokine.

Unravelling the Association Between Amyloid-PET and Cerebrospinal Fluid Biomarkers in the Alzheimer’s Disease Spectrum: Who Really Deserves an A+?

D. Galimberti, C. Fenoglio, E. Scarpini, 2021, Journal of Alzheimer's Disease.

Testing the 2018 NIA-AA research framework in a retrospective large cohort of patients with cognitive impairment: from biological biomarkers to clinical syndromes

D. Galimberti, C. Fenoglio, E. Scarpini, 2019, Alzheimer's Research & Therapy.

CSF β-amyloid as a putative biomarker of disease progression in multiple sclerosis

M. Bozzali, D. Galimberti, C. Fenoglio, 2017, Multiple sclerosis.

Alemtuzumab in multiple sclerosis during the COVID-19 pandemic: A mild uncomplicated infection despite intense immunosuppression

D. Galimberti, E. Scarpini, M. D. De Riz, 2020, Multiple sclerosis.

Language impairment in the genetic forms of behavioural variant frontotemporal dementia

Jennifer M. Nicholas, M. Freedman, R. Keren, 2022, Journal of Neurology.

A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

Jennifer M. Nicholas, M. Freedman, S. Ourselin, 2021, Molecular Neurodegeneration.

Sciatic endometriosis presenting as periodic (catamenial) sciatic radiculopathy

N. Bresolin, D. Galimberti, E. Scarpini, 2012, Journal of Neurology.

Theme 08 - Clinical Imaging and Electrophysiology

Jennifer M. Nicholas, M. Freedman, R. Keren, 2022, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.

Balò’s concentric sclerosis: still to be considered as a variant of multiple sclerosis?

D. Galimberti, E. Scarpini, S. Avignone, 2015, Neurological Sciences.

Association of Superficial White Matter Alterations with Cerebrospinal Fluid Biomarkers and Cognitive Decline in Neurodegenerative Dementia

A. Leemans, A. Bianchi, D. Galimberti, 2021, Journal of Alzheimer's Disease.

Caregiver Tele-Assistance for Reduction of Emotional Distress During the COVID-19 Pandemic. Psychological Support to Caregivers of People with Dementia: The Italian Experience.

D. Galimberti, E. Scarpini, A. Nobili, 2021, Journal of Alzheimer's disease : JAD.

Niemann-Pick Type C 1 (NPC1) and NPC2 Gene Variability in Demented Patients with Evidence of Brain Amyloid Deposition.

D. Galimberti, C. Fenoglio, E. Scarpini, 2021, Journal of Alzheimer's disease : JAD.

Detection of the SQSTM1 Mutation in a Patient with Early-Onset Hippocampal Amnestic Syndrome.

D. Galimberti, C. Fenoglio, E. Scarpini, 2020, Journal of Alzheimer's disease : JAD.

Profiling of Specific Gene Expression Pathways in Peripheral Cells from Prodromal Alzheimer's Disease Patients.

D. Galimberti, C. Fenoglio, E. Scarpini, 2018, Journal of Alzheimer's disease : JAD.

Amyloid PET imaging and dementias: potential applications in detecting and quantifying early white matter damage

M. Bozzali, D. Galimberti, C. Fenoglio, 2022, Alzheimer's research & therapy.

Clinical features and disease course of patients with acute ischaemic stroke just before the Italian index case: Was COVID-19 already there?

N. Bresolin, S. Corti, D. Galimberti, 2021, Internal and Emergency Medicine.

Cerebrospinal Fluid Level of Aquaporin4: A New Window on Glymphatic System Involvement in Neurodegenerative Disease?

D. Galimberti, C. Fenoglio, E. Scarpini, 2019, Journal of Alzheimer's disease : JAD.

Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study

Nick C Fox, Jennifer M. Nicholas, M. Freedman, 2022, Journal of Neuroinflammation.

Conversion Disorders Across Psychiatry and Neurology

E. Scarpini, A. Arighi, T. Carandini, 2018, Clinical Cases in Psychiatry: Integrating Translational Neuroscience Approaches.

Testing the 2018 NIA-AA research framework in a retrospective large cohort of patients with cognitive impairment: from biological biomarkers to clinical syndromes

D. Galimberti, C. Fenoglio, E. Scarpini, 2019, Alzheimer's Research & Therapy.

Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohort

Jennifer M. Nicholas, M. Freedman, R. Keren, 2023, Journal of the Neurological Sciences.

Klotho Gene Expression Is Decreased in Peripheral Blood Mononuclear Cells in Patients with Alzheimer's Disease and Frontotemporal Dementia.

D. Galimberti, C. Fenoglio, E. Scarpini, 2023, Journal of Alzheimer's disease : JAD.

Predominant right temporal lobe atrophy: Clinical, neuropsychological and structural differences based on amyloid status.

D. Galimberti, C. Fenoglio, E. Scarpini, 2023, European journal of neurology.

Myoinositol content in the human brain is modified by transcranial direct current stimulation in a matter of minutes: A 1H‐MRS study

A. Priori, S. Marceglia, F. Cogiamanian, 2008, Magnetic resonance in medicine.

Autosomal Dominant Frontotemporal Lobar Degeneration Due to the C9ORF72 Hexanucleotide Repeat Expansion: Late-Onset Psychotic Clinical Presentation

M. Filippi, M. Franceschi, F. Agosta, 2013, Biological Psychiatry.

Altered Extracellular Vesicle miRNA Profile in Prodromal Alzheimer’s Disease

D. Galimberti, C. Fenoglio, E. Scarpini, 2023, International journal of molecular sciences.

Circulating miRNAs as potential biomarkers in Alzheimer’s disease

D. Galimberti, C. Fenoglio, E. Scarpini, 2013 .

Telemedicine for cognitive impairment: a telephone survey of patients’ experiences with neurological video consultation

S. Barbieri, R. Ferrucci, E. Scarpini, 2023, Neurological Sciences.

Diagnostic accuracy of research criteria for prodromal frontotemporal dementia

Y. Pijnenburg, T. Rittman, B. Nacmias, 2024, Alzheimer's Research & Therapy.

Clinical validity of the Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB) in Mild Cognitive Impairment and Alzheimer’s Disease

M. Cotelli, F. Rossetto, E. Catricalà, 2024, Alzheimer's research & therapy.

Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia.

P. Mazzanti, C. Mussi, D. Cucinotta, 2020, Journal of the American Medical Directors Association.