J P Sanchez

New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.

J. Domagala, J M Domagala, L D Hanna, 1986, Journal of medicinal chemistry.

Quinolone antibacterial agents substituted at the 7-position with spiroamines. Synthesis and structure-activity relationships.

J P Sanchez, J. Sánchez, T P Culbertson, 1990, Journal of medicinal chemistry.

Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship.

S. Hagen, J. Domagala, S E Hagen, 1991, Journal of medicinal chemistry.

Effect of lipophilicity at N-1 on activity of fluoroquinolones against mycobacteria.

J. Domagala, S. Gracheck, M. Shapiro, 1995, Journal of medicinal chemistry.