Yantao He

发表

Negative regulation of TLR signaling in myeloid cells—implications for autoimmune diseases

Zhon-Yin Zhang, J. Buckner, J. Hamerman, 2016, Immunological reviews.

Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.

Nunzio Bottini, Sheng Li, Tong Liu, 2011, Journal of medicinal chemistry.

Small molecule tools for functional interrogation of protein tyrosine phosphatases

Zhon-Yin Zhang, Zhong-Yin Zhang, Yantao He, 2013, The FEBS journal.

Derivatives of Salicylic Acid as Inhibitors of YopH in Yersinia pestis

Chung F. Wong, Zunnan Huang, Zhon-Yin Zhang, 2010, Chemical biology & drug design.

Negative Regulation of Stat3 by Activating PTPN11 Mutants Contributes to the Pathogenesis of Noonan Syndrome and Juvenile Myelomonocytic Leukemia*

Xin-Yuan Fu, W. Shou, R. Chan, 2009, The Journal of Biological Chemistry.

Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.

Sanjai Kumar, Bo Zhou, Zhon-Yin Zhang, 2008, Journal of the American Chemical Society.

Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice

R. DiMarchi, D. Perez-Tilve, B. Finan, 2022, Molecular metabolism.

Cell Signaling Associated with Autoimmunity Impairs B Cutting Edge: The PTPN22 Allelic Variant

T. Habib, Zhon-Yin Zhang, J. Buckner, 2009 .

Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis Regimen.

P. Karakousis, Zhon-Yin Zhang, F. Burrows, 2016, ACS infectious diseases.

Therapeutic Potential of Menstrual Blood-Derived Stem Cell Transplantation for Intrauterine Adhesions

Yantao He, Yun Ye, Yanhua Han, 2022, Frontiers in Surgery.

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.

Jie Xu, Zhon-Yin Zhang, Zhong-Yin Zhang, 2013, Journal of medicinal chemistry.

Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).

R. Chan, Zhon-Yin Zhang, Zhihong Yu, 2010, Journal of medicinal chemistry.

The therapeutic potential of bone marrow mesenchymal stem cells in premature ovarian failure

Dongmei Chen, Huiming Ma, Yantao He, 2018, Stem Cell Research & Therapy.

A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus.

N. Bottini, F. Arnett, Javier Martín, 2008, Human molecular genetics.

Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT.

R. Negro, Zhon-Yin Zhang, L. Laurenti, 2012, Blood.

The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Hematopoietic Progenitor Hyperproliferation and Malignant Disease In Vivo

Menggang Yu, G. Sandusky, H. Boswell, 2012, Leukemia.

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.

G. Sandusky, H. Martin, G. Feng, 2012, Blood.

Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors.

Zhon-Yin Zhang, Yantao He, R. He, 2012, Bioorganic & medicinal chemistry.

Akt2 inhibits the activation of NFAT in lymphocytes by modulating calcium release from intracellular stores.

R. Geahlen, V. A. Martin, L. Parker, 2012, Cellular signalling.

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.

Jun O. Liu, C. Wells, J. Shim, 2015, ACS medicinal chemistry letters.

A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.

J. Dixon, Zhon-Yin Zhang, Yan Zhang, 2015, Bioorganic & medicinal chemistry.

Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases

Andy Hudmon, Bo Zhou, Zhon-Yin Zhang, 2007, Proceedings of the National Academy of Sciences.

Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling1

T. Habib, Zhon-Yin Zhang, J. Buckner, 2009, The Journal of Immunology.

Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

Yuehong Wang, Yan Liu, Jianyu Zheng, 2010, Proceedings of the National Academy of Sciences.

A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.

Nunzio Bottini, N. Bottini, Zhon-Yin Zhang, 2013, Journal of medicinal chemistry.

Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis.

Zhon-Yin Zhang, A. Gunawan, Yantao He, 2013, Chemical communications.

Cutting Edge Cutting Edge : The PTPN 22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling 1

T. Habib, Zhon-Yin Zhang, J. Buckner, 2009 .

The therapeutic potential of bone marrow mesenchymal stem cells in premature ovarian failure

Yantao He, Dongmei Chen, Huiming Ma, 2018, Stem Cell Research & Therapy.

A Facile Hydroxyindole Carboxylic Acid Based Focused Library Approach for Potent and Selective Inhibitors of Mycobacterium Protein Tyrosine Phosphatase B

Jie Xu, Zhon-Yin Zhang, A. Gunawan, 2013, ChemMedChem.

Double Click Reaction for the Acquisition of a Highly Potent and Selective mPTPB Inhibitor

Jie Xu, Zhon-Yin Zhang, Zhihong Yu, 2010, ChemMedChem.