N. Ramamoorthi

发表

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Jinfeng Liu, Saritha Kusam, Jeffrey Tom, 2015, Nature.

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)

Daniele Di Mauro, J. Hackney, I. McInnes, 2019, Annals of the rheumatic diseases.

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

S. Kummerfeld, M. Barnes, D. M. van der Heijde, 2019, Cell reports.

Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis

Z. Modrušan, Jason A. Vander Heiden, P. Wolters, 2020, Cell reports. Medicine.

Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor Fenebrutinib (GDC‐0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial

J. Galanter, D. Isenberg, L. Chinn, 2021, Arthritis & rheumatology.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2017, JCI insight.

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

M. Barnes, D. M. van der Heijde, R. Landewé, 2019, Annals of the rheumatic diseases.

Tick Saliva Immunosuppressor, Salp15 Cutting Edge: CD4 Is the Receptor for the

E. Fikrig, C. Yengo, J. Anguita, 2013 .

Cutting Edge: CD4 Is the Receptor for the Tick Saliva Immunosuppressor, Salp151

Ashish, E. Fikrig, C. Yengo, 2006, The Journal of Immunology.

IL-27 promotes T cell–dependent colitis through multiple mechanisms

L. Diehl, M. Batten, N. Kljavin, 2011, The Journal of experimental medicine.

Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double‐Blind, Phase II Trial

Stanley B. Cohen, J. Galanter, M. Genovese, 2020, Arthritis & rheumatology.

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells

S. Tangye, D. Danilenko, M. Batten, 2010, The Journal of experimental medicine.

Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva.

T. van der Poll, E. Fikrig, R. D. Beer, 2008, Journal of Infectious Diseases.

Coinfection with Borrelia burgdorferi sensu stricto and Borrelia garinii alters the course of murine Lyme borreliosis.

T. van der Poll, E. Fikrig, P. Speelman, 2007, FEMS immunology and medical microbiology.

A novel family of anticoagulants from the saliva of Ixodes scapularis

R. Koski, E. Fikrig, S. Narasimhan, 2002, Insect molecular biology.

Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.

Matthew S. Johnson, M. Ultsch, J. Veal, 2022, Journal of medicinal chemistry.

The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks

E. Fikrig, Daniel C. Desrosiers, J. Radolf, 2007, Molecular microbiology.

LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation

A. Wuster, T. Behrens, J. Monroe, 2018, The Journal of Immunology.

Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity

E. Kenigsberg, M. Dubinsky, M. Clatworthy, 2022, Nature Medicine.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2018, Nature Communications.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2018, Nature Communications.

The Lyme disease agent exploits a tick protein to infect the mammalian host

R. Koski, E. Fikrig, S. Narasimhan, 2005, Nature.

TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi

Ruth R. Montgomery, E. Fikrig, S. Telford, 2004, Cell.

The Tick Salivary Protein Salp15 Inhibits the Killing of Serum-Sensitive Borrelia burgdorferi Sensu Lato Isolates

E. Fikrig, A. V. van Dam, N. Ramamoorthi, 2008, Infection and Immunity.

Salp15, an ixodes scapularis salivary protein, inhibits CD4(+) T cell activation.

E. Fikrig, P. Askenase, J. Anguita, 2002, Immunity.

Identification of Salp15 homologues in Ixodes ricinus ticks.

E. Fikrig, A. Nijhof, F. Jongejan, 2007, Vector borne and zoonotic diseases.

Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

J. DeVoss, D. Seshasayee, W. Sandoval, 2016, Nature.

The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation

J. Hackney, C. Pitzalis, M. Townsend, 2019, The Journal of Immunology.

Depletion of major pathogenic cells in asthma by targeting CRTh2.

I. Hötzel, J. Payandeh, D. Yan, 2016, JCI insight.

ACTIVATION OF HUMAN MAST CELLS TO DOWN- REGULATE MONOCYTE-MEDIATED IMMUNE RESPONSES Chapter 6

T. Huizinga, R. Toes, G. Marone, 2016 .

Ability of Interleukin‐33– and Immune Complex–Triggered Activation of Human Mast Cells to Down‐Regulate Monocyte‐Mediated Immune Responses

G. Marone, J. Suurmond, C. Pitzalis, 2015, Arthritis & rheumatology.

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

J. Hackney, D. Heijde, I. McInnes, 2019, Annals of the rheumatic diseases.

An interleukin 6 responsive plasma cell signature is associated with disease progression in systemic sclerosis interstitial lung disease

Z. Modrušan, T. Ramalingam, J. Arron, 2023, iScience.

Ability of Interleukin‐33– and Immune Complex–Triggered Activation of Human Mast Cells to Down‐Regulate Monocyte‐Mediated Immune Responses

G. Marone, J. Suurmond, C. Pitzalis, 2015, Arthritis & rheumatology.

Depletion of major pathogenic cells in asthma by targeting CRTh2.

I. Hötzel, J. Payandeh, D. Yan, 2016, JCI insight.