Z. Tu

发表

Radiosynthesis and characterization of a carbon-11 PET tracer for receptor-interacting protein kinase 1.

J. Perlmutter, Qianwa Liang, Tianyu Huang, 2022, Nuclear medicine and biology.

Synthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-α receptors.

R. Mach, R. Gropler, M. Welch, 2012, Bioorganic & medicinal chemistry letters.

Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (-)-[18F]TZ3108 in rodent and the nonhuman primate brain.

J. Perlmutter, X. Zhang, Hongjun Jin, 2017, Bioorganic & medicinal chemistry.

Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors.

Xiaoxia Lu, Jinbin Xu, R. Luedtke, 2011, Journal of medicinal chemistry.

Radiosynthesis and biological evaluation of a promising sigma(2)-receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer.

R. Mach, H. Kung, M. Kung, 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Characterization of a novel iodinated sigma-2 receptor ligand as a cell proliferation marker.

R. Mach, H. Kung, M. Kung, 2006, Nuclear medicine and biology.

Synthesis and In Vivo Evaluation of 2 High-Affinity 76Br-Labeled σ2-Receptor Ligands

R. Mach, M. Welch, D. Rowland, 2006 .

Neuroprotective effects of high affinity sigma 1 receptor selective compounds

R. Mach, J. Simpkins, Shao-Hua Yang, 2012, Brain Research.

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

R. Hotchkiss, R. Mach, Katherine C. Chang, 2011, Nature communications.

Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.

Yi Su, J. Perlmutter, X. Zhang, 2016, Nuclear medicine and biology.

Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation.

R. Mach, Xuyi Yue, P. Kotzbauer, 2018, Bioorganic & medicinal chemistry letters.

PET IMAGING OF THE PHARMACOKINETICS OF SMALL MOLECULAR‐WEIGHT DRUGS

S. Moerlein, Z. Tu, 2013 .

Differential Sphingosine-1-Phosphate Receptor-1 Protein Expression in the Dorsolateral Prefrontal Cortex Between Schizophrenia Type 1 and Type 2

G. Chand, C. Rhodes, Hao Jiang, 2022, Frontiers in Psychiatry.

Synthesis and in vitro pharmacological evaluation of indolyl carboxylic amide analogues as D3 dopamine receptor selective ligands.

R. Mach, R. Luedtke, Z. Tu, 2013, MedChemComm.

Carbon-11 labeled σ2 receptor ligands for imaging breast cancer

R. Mach, C. Dence, M. Welch, 2005 .

Glycan array analysis of the antigen repertoire targeted by tumor-binding antibodies.

S. Achilefu, Baomei Wang, Z. Tu, 2012, Bioorganic & medicinal chemistry letters.

Quantitative Receptor-Based Imaging of Tumor Proliferation with the Sigma-2 Ligand [18F]ISO-1

R. Mach, M. You, D. Rowland, 2013, PloS one.

Endogenous dopamine (DA) competes with the binding of a radiolabeled D3 receptor partial agonist in vivo: A positron emission tomography study

M. Mintun, R. Mach, J. Perlmutter, 2011, Synapse.

In Vivo Characterization of Two 18F-Labeled PDE10A PET Radioligands in Nonhuman Primate Brains.

Yi Su, J. Perlmutter, X. Zhang, 2018, ACS chemical neuroscience.

Comparison of [11C]TZ1964B and [18F]MNI659 for PET imaging brain PDE10A in nonhuman primates

Yi Su, J. Perlmutter, Hongjun Jin, 2016, Pharmacology research & perspectives.

Comparison of [11C]TZ1964B and [18F]MNI659 for PET imaging brain PDE10A in nonhuman primates

Yi Su, J. Perlmutter, Hongjun Jin, 2016, Pharmacology research & perspectives.

A promising carbon-11-labeled sphingosine-1-phosphate receptor 1-specific PET tracer for imaging vascular injury

X. Zhang, Hongjun Jin, Yongjian Liu, 2017, Journal of Nuclear Cardiology.

Preclinical evaluation of the novel monoclonal antibody H6-11 for prostate cancer imaging.

Hongjun Jin, Yongjian Liu, S. Lapi, 2013, Molecular pharmaceutics.

Synthesis and In Vivo Evaluation of 2 High-Affinity 76Br-Labeled s2-Receptor Ligands

R. Mach, M. Welch, D. Ponde, 2006 .

4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies

R. Mach, F. Ntie‐Kang, S. M. Efange, 2016, Chemistry Central Journal.

Radiosynthesis and in vivo evaluation of a novel σ1 selective PET ligand.

J. Perlmutter, X. Zhang, Hongjun Jin, 2014, MedChemComm.

In vitro characterization of [3H]VAT in cells, animal and human brain tissues for vesicular acetylcholine transporter.

J. Perlmutter, Qianwa Liang, T. Benzinger, 2021, European journal of pharmacology.

In vitro and ex vivo characterization of (-)-TZ659 as a ligand for imaging the vesicular acetylcholine transporter.

J. Perlmutter, X. Zhang, Hongjun Jin, 2015, European journal of pharmacology.

Synthesis and Evaluation of 15-(4-(2-[ 18 F]Fluoroethoxy)phenyl)pentadecanoic Acid: a Potential PET Tracer for Studying Myocardial Fatty Acid Metabolism

R. Mach, C. Dence, P. Herrero, 2011 .

Absorbed radiation dosimetry of the D3-specific PET radioligand [18F]FluorTriopride estimated using rodent and nonhuman primate.

R. Mach, M. Karimi, J. Perlmutter, 2016, American journal of nuclear medicine and molecular imaging.

Synthesis and in vivo evaluation of [11C]PJ34, a potential radiotracer for imaging the role of PARP-1 in necrosis.

R. Mach, C. Dence, M. Welch, 2005, Nuclear medicine and biology.

Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents.

Lin Qiu, Hongzhen Hu, Qianwa Liang, 2020, Bioorganic & medicinal chemistry letters.

Design, synthesis, and in vitro bioactivity evaluation of fluorine-containing analogues for sphingosine-1-phosphate 2 receptor.

R. Klein, Z. Tu, Zonghua Luo, 2019, Bioorganic & medicinal chemistry.

Upregulated Sphingosine 1-Phosphate Receptor 1 Expression in Human and Murine Atherosclerotic Plaques

R. Gropler, Hongjun Jin, Xuyi Yue, 2018, Molecular Imaging and Biology.

Cholinergic imbalance in lumbar spinal cord of a rat model of multiple sclerosis

Hongjun Jin, Xuyi Yue, Z. Tu, 2018, Journal of Neuroimmunology.

Synthesis and biological characterization of stable and radioiodinated (+/-)-trans-2-hydroxy-3-P[4-(3-iodophenyl)piperidyl]-1,2,3,4-tetrahydronaphthalene (3'-IBVM).

R. Mach, S. Efange, Z. Tu, 2000, Nuclear medicine and biology.

Synthesis and characterization of [125I]TZ6544, a promising radioligand for investigating sphingosine-1-phosphate receptor 2.

R. Klein, Qianwa Liang, Hao Jiang, 2020, Nuclear medicine and biology.

Exploration of Sulfur‐Containing Analogues for Imaging Vesicular Acetylcholine Transporter in the Brain

J. Perlmutter, Hongjun Jin, Jiwei Gu, 2018, ChemMedChem.

Automated production of [¹⁸F]VAT suitable for clinical PET study of vesicular acetylcholine transporter.

J. Perlmutter, X. Zhang, S. Moerlein, 2016, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups.

X. Zhang, Xiaoxia Lu, Jinbin Xu, 2012, Bioorganic & medicinal chemistry.

Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain.

J. Perlmutter, Hongzhen Hu, Qianwa Liang, 2019, Organic & biomolecular chemistry.

Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.

R. Mach, S. Efange, Z. Tu, 2010, Journal of medicinal chemistry.

Synthesis, In Vitro and In Vivo Evaluation of 18F-labeled PET Ligands for Imaging the Vesicular Acetylcholine Transporter

R. Mach, L. Jones, S. Efange, 2009 .

Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease

J. Perlmutter, T. Egan, Hongjun Jin, 2018, European journal of pharmacology.

Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate.

X. Zhang, J. Perlmutter, Hongjun Jin, 2017, Organic & biomolecular chemistry.

In vivo Characterization of Four 18F-Labeled S1PR1 Tracers for Neuroinflammation

R. Gropler, Yun Zhou, T. Benzinger, 2020, Molecular Imaging and Biology.

Design and synthesis of pyrazolopyridine derivatives as sphingosine 1-phosphate receptor 2 ligands.

R. Klein, Xuyi Yue, Z. Tu, 2017, Bioorganic & medicinal chemistry letters.

Syntheses and in vitro biological evaluation of S1PR1 ligands and PET studies of four F-18 labeled radiotracers in the brain of nonhuman primates.

R. Gropler, J. Perlmutter, Delphine L. Chen, 2018, Organic & biomolecular chemistry.

Syntheses and in vitro evaluation of new S1PR1 compounds and initial evaluation of a lead F-18 radiotracer in rodents.

Z. Tu, Junbin Han, Adam J Rosenberg, 2018, European journal of medicinal chemistry.

Design, Synthesis, and In Vitro and In Vivo Evaluation of an (18)F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P1) PET Tracer.

Steven J Brown, Hongjun Jin, Xuyi Yue, 2016, Journal of medicinal chemistry.

Radiosynthesis and Evaluation of a C-11 Radiotracer for Transient Receptor Potential Canonical 5 in the Brain

V. Bolshakov, Lin Qiu, J. Perlmutter, 2022, Molecular Imaging and Biology.

Acute Rodent Tolerability, Toxicity, and Radiation Dosimetry Estimates of the S1P1-Specific Radioligand [11C]CS1P1

R. Gropler, R. Laforest, L. Jones, 2019, Molecular Imaging and Biology.

PET Study of Sphingosine-1-Phosphate Receptor 1 Expression in Response to Vascular Inflammation in a Rat Model of Carotid Injury

Hongjun Jin, Xuyi Yue, D. Abendschein, 2017, Molecular imaging.

A potent and selective C-11 labeled PET tracer for imaging sphingosine-1-phosphate receptor 2 in the CNS demonstrates sexually dimorphic expression.

R. Klein, Hongjun Jin, Xuyi Yue, 2015, Organic & biomolecular chemistry.

PET Imaging Study of S1PR1 Expression in a Rat Model of Multiple Sclerosis

Hongjun Jin, Xuyi Yue, Z. Tu, 2016, Molecular Imaging and Biology.

Phase 1 Evaluation of 11C-CS1P1 to Assess Safety and Dosimetry in Human Participants

T. Benzinger, R. Gropler, J. Perlmutter, 2022, The Journal of Nuclear Medicine.

Automated production of a sphingosine-1 phosphate receptor 1 (S1P1) PET radiopharmaceutical [11C]CS1P1 for human use.

J. Perlmutter, T. Benzinger, Delphine L. Chen, 2019, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Radiation dosimetry of [18F]VAT in nonhuman primates

M. Karimi, J. Perlmutter, R. Laforest, 2015, EJNMMI Research.

Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response

J. Perlmutter, T. Egan, Hongjun Jin, 2017, Nuclear medicine communications.

A promising F-18 labeled PET radiotracer (-)-[18F]VAT for assessing the VAChT in vivo

M. Karimi, J. Perlmutter, Hongjun Jin, 2015 .

Syntheses and Radiosyntheses of Two Carbon-11 Labeled Potent and Selective Radioligands for Imaging Vesicular Acetylcholine Transporter

J. Perlmutter, Z. Tu, S. Parsons, 2014, Molecular Imaging and Biology.

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules.

R. Mach, Chia-Ju Hsieh, E. Petersson, 2018, ACS chemical neuroscience.

A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands.

Z. Tu, Adam J Rosenberg, Hui Liu, 2015, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[3H]4‐(dimethylamino)‐N‐(4‐(4‐(2‐methoxyphenyl)piperazin‐1‐yl) butyl)benzamide: A selective radioligand for dopamine D3 receptors. II. Quantitative analysis of dopamine D3 and D2 receptor density ratio in the caudate‐putamen

Jinbin Xu, Wenhua Chu, M. Mintun, 2010, Synapse.

Synthesis and Characterization of a Specific Iodine‐125‐Labeled TRPC5 Radioligand

Hongzhen Hu, Qianwa Liang, Hao Jiang, 2020, ChemMedChem.

Synthesis and in vitro characterization of cinnoline and benzimidazole analogues as phosphodiesterase 10A inhibitors.

Hongjun Jin, Z. Tu, Hao Yang, 2015, Bioorganic & medicinal chemistry letters.

N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.

David E Reichert, R. Mach, M. Welch, 2005, Journal of medicinal chemistry.

Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer’s Disease and Parkinson’s Disease Treatment (2011–2020)

Z. Tu, Yanbo Yu, Xuefei Li, 2021, Molecules.

Heteroaromatic and aniline derivatives of piperidines as potent ligands for vesicular acetylcholine transporter.

J. Perlmutter, Hongjun Jin, D. Zeng, 2013, Journal of medicinal chemistry.

2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization.

R. Papke, M. Kung, S. Efange, 2001, Journal of medicinal chemistry.

Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

Robert H Mach, Robert R Luedtke, Jinbin Xu, 2005, Bioorganic & medicinal chemistry.

Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter.

R. Mach, L. Jones, S. Efange, 2009, Journal of medicinal chemistry.

Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro

R. Mach, Chia-Ju Hsieh, P. Kotzbauer, 2018, ACS omega.

The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine

Jonathan B. Mitchem, R. Mach, W. Hawkins, 2010, Molecular Cancer.

Baseline Microglial Activation Correlates With Brain Amyloidosis and Longitudinal Cognitive Decline in Alzheimer Disease

A. Fagan, M. Mintun, J. Morris, 2022, Neurology: Neuroimmunology & Neuroinflammation.

C-11 radiochemistry in cancer imaging applications.

R. Mach, Z. Tu, 2010, Current topics in medicinal chemistry.

Synthesis and in vitro biological evaluation of pyrazole group-containing analogues for PDE10A.

Haiying Zhou, Hongjun Jin, Haiying Zhou, 2013, MedChemComm.

Low-Dose Augmentation With Buprenorphine for Treatment-Resistant Depression: A Multisite Randomized Controlled Trial With Multimodal Assessment of Target Engagement

Yiyun Huang, D. Barch, B. Mulsant, 2021, Biological psychiatry global open science.

PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection

R. Gropler, J. Perlmutter, R. Klein, 2021, Molecular imaging.

Radiosynthesis and Evaluation of A Fluorine-18 Radiotracer [18F]FS1P1 for Imaging Sphingosine-1-Phosphate Receptor 1

Lin Qiu, R. Gropler, J. Perlmutter, 2022, Organic & Biomolecular Chemistry.

Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors.

R. Gropler, J. Perlmutter, B. Rogers, 2020, European journal of medicinal chemistry.

Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils.

R. Mach, B. Bacskai, A. D'avignon, 2015, Journal of medicinal chemistry.

Differential sphingosine-1-phosphate receptor-1 (S1PR1) protein expressions in the dorsolateral prefrontal cortex between schizophrenia Type 1 and Type 2

D. Wong, M. Brier, T. Benzinger, 2021, bioRxiv.

Synthesis and evaluation of 15-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)pentadecanoic acid: a potential PET tracer for studying myocardial fatty acid metabolism.

R. Mach, C. Dence, P. Herrero, 2010, Bioconjugate chemistry.

Functional assays to define agonists and antagonists of the sigma-2 receptor.

R. Mach, C. Zeng, S. Vangveravong, 2014, Analytical biochemistry.

[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.

R. Mach, L. Jones, S. Vangveravong, 2005, European journal of pharmacology.

Fluorine-18-labeled benzamide analogues for imaging the sigma2 receptor status of solid tumors with positron emission tomography.

R. Mach, M. Welch, L. Jones, 2007, Journal of medicinal chemistry.

Synthesis and Structure − Activity Relationship Studies of Conformationally Flexible Tetrahydroisoquinolinyl Triazole Carboxamide and Triazole Substituted Benzamide Analogues as σ 2 Receptor Ligands

R. Mach, C. Zeng, Jinbin Xu, 2014 .

In Vitro and In Vivo Investigation of S1PR1 Expression in the Central Nervous System Using [3H]CS1P1 and [11C]CS1P1.

Gregory F. Wu, Lin Qiu, R. Gropler, 2021, ACS chemical neuroscience.

Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.

J. Perlmutter, Hongjun Jin, Xuyi Yue, 2015, Bioorganic & medicinal chemistry.

In Vitro and In Vivo Characterization of Two C-11-Labeled PET Tracers for Vesicular Acetylcholine Transporter

J. Perlmutter, Hongjun Jin, Z. Tu, 2014, Molecular Imaging and Biology.

Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate.

J. Perlmutter, Hongjun Jin, Z. Tu, 2015, Journal of medicinal chemistry.

Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate.

Yi Su, Jinda Fan, Hongjun Jin, 2014, Bioorganic & medicinal chemistry.

Synthesis and in vitro evaluation of new analogues as inhibitors for phosphodiesterase 10A.

R. Mach, Jinbin Xu, Z. Tu, 2011, European journal of medicinal chemistry.

Synthesis and pharmacological evaluation of fluorine-containing D₃ dopamine receptor ligands.

R. Mach, Jinbin Xu, R. Luedtke, 2011, Journal of medicinal chemistry.

Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter.

J. Perlmutter, Xuyi Yue, Z. Tu, 2018, Bioorganic & medicinal chemistry letters.

Kinetic modeling of [18F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non‐human primate brain

Yi Su, J. Perlmutter, Hongjun Jin, 2018, Journal of neurochemistry.

[3H]4‐(Dimethylamino)‐N‐[4‐(4‐(2‐methoxyphenyl)piperazin‐ 1‐yl)butyl]benzamide, a selective radioligand for dopamine D3 receptors. I. In vitro characterization

M. Mintun, R. Mach, J. Perlmutter, 2009, Synapse.

Positron emission tomography imaging of dopamine D2 receptors using a highly selective radiolabeled D2 receptor partial agonist

Joel S. Perlmutter, Robert H. Mach, Shihong Li, 2013, NeuroImage.

Synthesis and characterization of selective dopamine D2 receptor antagonists.

Robert H Mach, Robert R Luedtke, Jinbin Xu, 2006, Bioorganic & medicinal chemistry.

Synthesis and evaluation of highly selective quinazoline-2,4-dione ligands for sphingosine-1-phosphate receptor 2.

R. Gropler, Z. Tu, Zonghua Luo, 2022, RSC medicinal chemistry.

Carbon-11 labeled sigma2 receptor ligands for imaging breast cancer.

R. Mach, C. Dence, M. Welch, 2005, Nuclear medicine and biology.

Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled sigma2-receptor ligands.

R. Mach, M. Welch, D. Rowland, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Chemical and enzyme-assisted syntheses of norbuprenorphine-3-β-D-glucuronide.

E. Kharasch, Z. Tu, Jinda Fan, 2011, Bioconjugate chemistry.

Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain.

Joel S Perlmutter, Kooresh I Shoghi, Robert H Mach, 2011, Bioorganic & medicinal chemistry.

Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein

R. Mach, Hongjun Jin, P. Kotzbauer, 2014, Applied sciences.

Current status of the development of PET radiotracers for imaging alpha synuclein aggregates in Lewy bodies and Lewy neurites

R. Mach, P. Kotzbauer, Z. Tu, 2017, Clinical and Translational Imaging.

Binding of the Radioligand SIL23 to α-Synuclein Fibrils in Parkinson Disease Brain Tissue Establishes Feasibility and Screening Approaches for Developing a Parkinson Disease Imaging Agent

R. Mach, J. Perlmutter, Jinbin Xu, 2013, PloS one.

Synthesis and in vitro evaluation of α-synuclein ligands.

P. Kotzbauer, Z. Tu, Jinquan Cui, 2012, Bioorganic & medicinal chemistry.

Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subject

Hui Liu, Yi Su, Joel S. Perlmutter, 2015, NeuroImage.

Carbon-11 labeled papaverine as a PET tracer for imaging PDE10A: radiosynthesis, in vitro and in vivo evaluation.

Robert H Mach, Jinbin Xu, Shihong Li, 2010, Nuclear medicine and biology.

C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production

X. Su, Yuanbao Li, Z. Tu, 2018, Cellular Physiology and Biochemistry.

Effect of cyclosporin A on the uptake of D3-selective PET radiotracers in rat brain.

R. Mach, L. Jones, Jinbin Xu, 2011, Nuclear medicine and biology.

Automated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM).

R. Mach, E. Kharasch, K. Sai, 2014, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Sigma-2 ligands induce tumour cell death by multiple signalling pathways

R. Hotchkiss, R. Mach, Katherine C. Chang, 2012, British Journal of Cancer.

Characterization of a S1PR2 specific 11C-labeled radiotracer in streptozotocin-induced diabetic murine model.

Lin Qiu, R. Gropler, Tianyu Huang, 2023, Nuclear medicine and biology.

Automated radiosynthesis of [11C]morphine for clinical investigation.

R. Mach, E. Kharasch, Konrad Meissner, 2011, Applied Radiation and Isotopes.

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.

R. Hotchkiss, R. Mach, Katherine C. Chang, 2011, Nature communications.

The impact of dopamine D2-like agonist/antagonist on [18F]VAT PET measurement of VAChT in the brain of nonhuman primates.

J. Perlmutter, Yun Zhou, Jiwei Gu, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Spatially constrained kinetic modeling with dual reference tissues improves 18F-flortaucipir PET in studies of Alzheimer disease

B. Ances, R. Gropler, J. Perlmutter, 2021, European Journal of Nuclear Medicine and Molecular Imaging.

PET imaging studies of brain S1PR1 expression in Parkinson disease

J. Perlmutter, L. Dugan, Yun Zhou, 2019 .

Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease

Andrei G. Vlassenko, Gloria Guzman Perez-Carillo, Nicole S. McKay, 2022, The Journal of Nuclear Medicine.

Discovery of a Promising Fluorine-18 Positron Emission Tomography Radiotracer for Imaging Sphingosine-1-Phosphate Receptor 1 in the Brain.

Lin Qiu, J. Perlmutter, T. Benzinger, 2023, Journal of medicinal chemistry.

Chromaproline and Chromaperidine, nicotine agonists, and Donepezil, cholinesterase inhibitor, enhance performance of memory tasks in ovariectomized rats

V. Luine, S. Efange, Z. Tu, 2002, Pharmacology Biochemistry and Behavior.

Design and synthesis of pyrazolopyridine derivatives as sphingosine 1-phosphate receptor 2 ligands.

R. Klein, Xuyi Yue, Z. Tu, 2017, Bioorganic & medicinal chemistry letters.