M. Lai

发表

Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

A. Kimchi, Ruey-Hwa Chen, Yung-Hsuan Wu, 2020, Cell Death & Disease.

Removal of Syndecan-1 Promotes TRAIL-Induced Apoptosis in Myeloma Cells

Yung-Hsuan Wu, M. Lai, Chenyin Yang, 2012, The Journal of Immunology.

Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation

Wen-Hsien Liu, M. Lai, Huey-Wen Hsiao, 2007, The EMBO journal.

Selective activation of NFAT by promyelocytic leukemia protein

M. Lai, Y-H Lo, C-C Wu, 2008, Oncogene.

Nuclear Factor of Activated T Cells c Is a Target of p38 Mitogen-Activated Protein Kinase in T Cells

H. Shih, M. Lai, S. Hsu, 2003, Molecular and Cellular Biology.

Paxillin phosphorylation by JNK and p38 is required for NFAT activation

M. Lai, W. Tsou, A. Chang, 2012, European journal of immunology.

Efficiency of Cytoplasmic Delivery by pH-Sensitive Liposomes to Cells in Culture

F. Szoka, J. Dijkstra, K. Hong, 1990, Pharmaceutical Research.

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

M. Lai, Kuo-Ting Lee, Chih-Yang Wang, 2016, Oncotarget.

Apoptotic signal of Fas is not mediated by ceramide.

S. Han, C. Chou, T. Luh, 1998, Blood.

Ezrin is a negative regulator of death receptor-induced apoptosis

S. Hsieh, W. Kuo, M. Lai, 2010, Oncogene.

IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells

M. Lai, Wan-Chen Hsieh, Ya‐Jen Chang, 2018, Nature Communications.

Deltex1 suppresses T cell function and is a biomarker for diagnosis and disease activity of systemic lupus erythematosus

Ming-Huang Chen, D. Chang, Chang-Youh Tsai, 2019, Rheumatology.

Deltex1 suppresses T cell function and is a biomarker for diagnosis and disease activity of systemic lupus erythematosus.

Ming-Huang Chen, D. Chang, Chang-Youh Tsai, 2019, Rheumatology.

Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo

S. Jiang, Wen-Hsien Liu, Ting-Fang Chou, 2015, Nature Communications.

HIF-2α is indispensable for regulatory T cell function

Alan Chuan-Ying Lai, Hsuan-Yin Pan, Shuting Mo, 2020, Nature Communications.

Hypoxia‐inducible factor 1α plays a predominantly negative role in regulatory T cell functions

M. Lai, Tzu-Sheng Hsu, 2018, Journal of leukocyte biology.

c-Jun NH2-terminal Kinase Activation Leads to a FADD-dependent but Fas Ligand-independent Cell Death in Jurkat T Cells*

M. Lai, Yun Chen, 2001, The Journal of Biological Chemistry.

T CELL RECEPTOR GENE USAGE IN THE RESPONSE TO X REPRESSOR cI PROTEIN An Apparent Bias in the Usage of a Va Gene Element

M. Gefter, J. Guillet, John A. Smith, 2003 .

Restricted V-(D)-J junctional regions in the T cell response to lambda-repressor. Identification of residues critical for antigen recognition.

M. Gefter, Y. Jang, M. Lai, 1990, Journal of immunology.

Infection‐induced inflammation from specific inborn errors of immunity to COVID‐19

Cheng-Lung Ku, M. Lai, I-Ting Chen, 2021, The FEBS journal.

Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap-/- mice.

M. Lai, S. Hsu, S. Miaw, 2014, Blood.

PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Inability to resolve speci fi c infection generates innate immunode fi ciency syndrome in Xiap 2 / 2 mice

M. Lai, S. Hsu, S. Miaw, 2014 .

Isolation and characterization of nuclear proteins that bind to T cell receptor V beta decamer motif.

C. Chung, M. Lai, Y. Hsueh, 1992, Journal of immunology.

Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling

You-Wen He, Yung-Hsuan Wu, Shuting Mo, 2015, The Journal of Immunology.

Atypical signaling defects prevent IL-2 gene expression in lpr/lpr CD4-CD8- cells.

S. Han, M. Lai, S. Hsu, 1998, Journal of biomedical science.

DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation

C. Chou, T. Luh, Huey-Lan Huang, 2003, Oncogene.

T cell receptor gene usage in the response to lambda repressor cI protein. An apparent bias in the usage of a V alpha gene element

M. Gefter, J. Smith, J. Guillet, 1988, The Journal of experimental medicine.

T cell epitope selection: dominance may be determined by both affinity for major histocompatibility complex and stoichiometry of epitope

M. Lai, C. Pan, W. F. Li, 1992, European journal of immunology.

Tumor suppressor death-associated protein kinase is required for full IL-1 (cid:1) production

A. Kimchi, W. Kuo, Ting-Fang Chou, 2011 .

Regulation of inflammation by DAPK

Ruey-Hwa Chen, M. Lai, 2014, Apoptosis.

Mitogen-activated Protein Kinase Kinase Antagonized Fas-associated Death Domain Protein–mediated Apoptosis by Induced FLICE-inhibitory Protein Expression

M. Lai, S. Hsu, J. Yeh, 1998, The Journal of experimental medicine.

Attenuation of Bone Mass and Increase of Osteoclast Formation in Decoy Receptor 3 Transgenic Mice*

Wan-Wan Lin, W. Fu, S. Hsieh, 2007, Journal of Biological Chemistry.

of thymocyte development Involvement of p38 mitogen activated protein kinase in different stages

Jiahuai Han, M. Lai, S. Hsu, 2013 .

Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development.

Jiahuai Han, M. Lai, S. Hsu, 2003, Blood.

Transcriptomic Analysis and C-Terminal Epitope Tagging Reveal Differential Processing and Signaling of Endogenous TLR3 and TLR7

Ting-Fang Wang, Chiung-Ya Chen, Ting-Fang Chou, 2021, Frontiers in Immunology.

Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy.

S. Jiang, Wen-Hsien Liu, Yung-Hsuan Wu, 2009, Immunity.

Receptor 3 Transgenic Mice Attenuation of Th 1 Response in Decoy HsiehYang

S. Hsieh, T. Hsu, M. Lai, 2005 .

Sensitization of Cells to TRAIL-induced Apoptosis by Decoy Receptor 3*

S. Hsieh, T. Hsu, M. Lai, 2004, Journal of Biological Chemistry.

The Tumor Suppressor Death-Associated Protein Kinase Targets to TCR-Stimulated NF-κB Activation1

Ruey-Hwa Chen, M. Lai, Li-Wen Fang, 2008, The Journal of Immunology.

NF-kappa B-dependent Fas ligand expression.

S. Han, H. H. Lee, M. Lai, 1999, European journal of immunology.

cAMP analogs prevent activation-induced apoptosis of T cell hybridomas.

M. Lai, M. Liou, Y. Yang, 1993, Journal of immunology.

Lymphoma Expression Degradation and Sustains Casitas B-Lineage q Deltex1 Promotes Protein Kinase C

Wen-Hsien Liu, M. Lai, Huey-Wen Hsiao, 2014 .

c-FLICE inhibitory protein expression inhibits T-cell activation

M. Lai, M-Z Lai, T-S Tai, 2004, Cell Death and Differentiation.

Atypical Signaling Defects Prevent IL-2 Gene Expression in lpr/lpr CD4–CD8– Cells

Hong-Erh Liang, M. Lai, S. Hsu, 1998, Journal of Biomedical Science.

T lymphocyte response to bacteriophage lambda repressor cI protein. Recognition of the same peptide presented by Ia molecules of different haplotypes.

D. Ross, M. Gefter, J. Smith, 1987, Journal of immunology.

Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells

S. Hsieh, Yung-Hsuan Wu, Fu-Yi Hsieh, 2022, Science advances.

Reactive oxygen species promote raft formation in T lymphocytes.

Huey-Lan Huang, M. Lai, W. Tsou, 2007, Free radical biology & medicine.

Deltex1 Promotes Protein Kinase Cθ Degradation and Sustains Casitas B-Lineage Lymphoma Expression

Wen-Hsien Liu, M. Lai, Huey-Wen Hsiao, 2014, The Journal of Immunology.

Interaction of peptide antigens and class II major histocompatibility complex antigens

M. Gefter, J. Guillet, John A. Smith, 1986, Nature.

Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation

S. Jiang, S-T Chen, W. Kuo, 2013, Cell Death and Differentiation.

production β IL-1 Tumor suppressor death-associated protein kinase is required for full

A. Kimchi, W. Kuo, Ruey-Hwa Chen, 2012 .

Tumor suppressor death-associated protein kinase is required for full IL-1β production.

A. Kimchi, W. Kuo, Ruey-Hwa Chen, 2011, Blood.

Deltex Regulates T-Cell Activation by Targeted Degradation of Active MEKK1

Wen-Hsien Liu, M. Lai, 2005, Molecular and Cellular Biology.

Selective contact during TCR recognition.

Y. Liaw, M. Lai, Y. Shen, 1996, International immunology.

Interleukin-3 Stimulation of mcl-1 Gene Transcription Involves Activation of the PU.1 Transcription Factor through a p38 Mitogen-Activated Protein Kinase-Dependent Pathway

H. Yang-Yen, Ju-Ming Wang, M. Lai, 2003, Molecular and Cellular Biology.

Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

A. Kimchi, Ruey-Hwa Chen, Yung-Hsuan Wu, 2020, Cell Death & Disease.

Regulation of inflammation by DAPK

Ruey-Hwa Chen, M. Lai, 2014, Apoptosis.

Immunological self, nonself discrimination.

A Sette, H. Grey, A. Sette, 1987, Science.

CREB Is One Component of the Binding Complex of the Ces-2/E2A-HLF Binding Element and Is an Integral Part of the Interleukin-3 Survival Signal

Changyuan Huang, Jyh-Rong Chao, Shern-Fwu Lee, 2001, Molecular and Cellular Biology.

Promyelocytic Leukemia Protein (PML) Functions as a Glucocorticoid Receptor Co-activator by Sequestering Daxx to the PML Oncogenic Domains (PODs) to Enhance Its Transactivation Potential*

Ming-Zong Lai, H. Shih, D. Ann, 2003, The Journal of Biological Chemistry.

Identical peptides recognized by MHC class I- and II-restricted T cells

M. Gefter, J. Smith, D. Perkins, 1989, The Journal of experimental medicine.

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

S. Liang, Yi-Ching Wang, Chun-Ming Chen, 2017, The Journal of clinical investigation.

Promyelocytic leukemia protein targets MK2 to promote cytotoxicity

H. Shih, Yung-Hsuan Wu, Fu-Yi Hsieh, 2021, EMBO reports.

NF‐κB‐dependent Fas ligand expression

Hsiu-Hsiang Lee, M. Lai, S. Hsu, 1999 .

Impaired TNFα-induced A20 expression in E1A/Ras-transformed cells

S. Benchimol, C. Mirtsos, W. Yeh, 2009, British Journal of Cancer.

CD28-costimulation activates cyclic AMP-responsive element-binding protein in T lymphocytes.

S. Ng, M. Lai, Y. Hsueh, 1997, Journal of immunology.

Ming-Zong Lai Targeted Degradation of Active MEKK 1 Deltex Regulates T-Cell Activation

Wen-Hsien Liu, M. Lai, 2005 .

Flexibility of the T cell receptor repertoire

D. Chou, Hong-Erh Liang, M. Lai, 1994, European journal of immunology.

A peptide binding weakly to the major histocompatibility molecule augments T cell responses

M. Lai, M. L. Feng, 1994, European journal of immunology.

p38 Mitogen-activated Protein Kinase Is Involved in Fas Ligand Expression*

Jiahuai Han, M. Lai, S. Hsu, 1999, The Journal of Biological Chemistry.

Phosphatidylinositide 3-Kinase Priming Couples c-FLIP to T Cell Activation*

Wan-Ni Yu, M. Lai, Li-Wen Fang, 2004, Journal of Biological Chemistry.

Nitric oxide increased interleukin‐4 expression in T lymphocytes

M. Lai, R.‐H. CHANG, M.‐H. LIN FENG, 1997, Immunology.

Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression

A. Kimchi, Ruey-Hwa Chen, Ting-Fang Chou, 2016, Nature Communications.

Increased p300 Expression Inhibits Glucocorticoid Receptor-T-Cell Receptor Antagonism but Does Not Affect Thymocyte Positive Selection

H. Shih, M. Lai, Cheng-Tai Yu, 2002, Molecular and Cellular Biology.

(CREB) Binding Protein Interaction Induced AMP-Responsive Element Binding Protein Multiple Signals Required for Cyclic

Cheng-Tai Yu, Hsiu-ming Shih, Ming-Zong Lai, 2013 .

Multiple Signals Required for Cyclic AMP-Responsive Element Binding Protein (CREB) Binding Protein Interaction Induced by CD3/CD28 Costimulation1

H. Shih, M. Lai, Cheng-Tai Yu, 2001, The Journal of Immunology.

Attenuation of Th1 Response in Decoy Receptor 3 Transgenic Mice1

Yung-Chi Chang, Ming-Zong Lai, S. Hsieh, 2005, The Journal of Immunology.

Overexpression of activation transcriptional factor 1 in lymphomas and in activated lymphocytes.

M. Lai, Y. Hsueh, 1995, Journal of immunology.

Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and human.

H. Shih, S. Jiang, W. Kuo, 2013, Blood.

Antagonism of p53-dependent apoptosis by mitogen signals.

M. Lai, Y. Lin, M. Lai, 1999, Cancer research.

Antagonism of p 53-dependent Apoptosis by Mitogen Signals 1

M. Lai, Young-Sun Lin, M. Lai, 1999 .

IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells

M. Lai, Wan-Chen Hsieh, Ya‐Jen Chang, 2018, Nature Communications.

c-FLIP is a target of the E3 ligase deltex1 in gastric cancer

M. Lai, P. Hsu, Tzu-Sheng Hsu, 2018, Cell Death & Disease.

Modulation of restricted class II T cell responses by peptides derived from self class II molecule

M. Gefter, M. Lai, Wan‐Fen Li, 1992, European journal of immunology.

Overexpression of mitogen‐activated protein kinase kinase kinase reversed cAMP inhibiton of NF‐χB in T cells

Hsiu-Hsiang Lee, M. Lai, Huang‐Yao Ho, 1997 .

the same peptide presented by Ia molecules of lambda repressor cI protein . Recognition of T lymphocyte response to bacteriophage

M. Gefter, J. Guillet, M. Lai, 2001 .

Sensitization of cells to TRAIL-induced apoptosis by decoy receptor 3.

S. Hsieh, T. Hsu, M. Lai, 2004, The Journal of biological chemistry.

Role of aromatic residues in the structure-function relationship of alpha-bungarotoxin.

M. Hung, M. Lai, M. Lai, 1982, Biochemistry.

Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development.

Jiahuai Han, M. Lai, S. Hsu, 2003, Blood.

c-FLIP is a target of the E3 ligase deltex1 in gastric cancer

M. Lai, P. Hsu, Tzu-Sheng Hsu, 2018, Cell Death & Disease.