Tinka Haydn

Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling.

M. Boerries, H. Busch, S. Fulda, 2018, Cancer letters.

Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells

S. Fulda, R. Schüle, E. Metzger, 2019, International journal of cancer.

Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells

S. Fulda, R. Schuele, E. Metzger, 2017, Cell Death & Disease.

Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.

S. Fulda, W. Sippl, M. Lübbert, 2018, European journal of medicinal chemistry.

Targeting BCL-2 proteins in pediatric cancer: Dual inhibition of BCL-XL and MCL-1 leads to rapid induction of intrinsic apoptosis.

S. Fulda, M. Vogler, Tinka Haydn, 2020, Cancer letters.

Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways

M. Boerries, S. Fulda, M. Vogler, 2019, Cell Death & Differentiation.

BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis

S. Fulda, M. Vogler, Tinka Haydn, 2018, Oncogene.

Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways

M. Boerries, S. Fulda, M. Vogler, 2019, Cell Death and Differentiation.