Warren L. Lee

Warren L. Lee, N. Filewod, 2015, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

The lung microvascular endothelium as a therapeutic target in severe influenza.

S. Mubareka, Susan M. Armstrong, Warren L. Lee, 2013, Antiviral research.

Influenza Infects Lung Microvascular Endothelium Leading to Microvascular Leak: Role of Apoptosis and Claudin-5

T. Moraes, Changsen Wang, Susan M. Armstrong, 2012, PloS one.

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.

G. Keller, M. Wheeler, Xuetao Sun, 2020, The Journal of clinical investigation.

The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice.

A. Advani, S. Advani, Warren L. Lee, 2020, Endocrinology.

CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery.

B. Heit, G. Fairn, Hoon-Ki Sung, 2019, American journal of physiology. Lung cellular and molecular physiology.

Transcellular vesicular transport in epithelial and endothelial cells: Challenges and opportunities

G. Fairn, Warren L. Lee, K. Fung, 2018, Traffic.

Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells

Arthur S Slutsky, Haibo Zhang, Yimin Li, 2016, Scientific Reports.

Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2–SR-BI Axis

B. Steinberg, N. Goldenberg, Changsen Wang, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Prostaglandin I2 Receptor Agonism Preserves β-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms

K. Thai, A. Advani, Syamantak Majumder, 2016, Diabetes.

IP RECEPTOR AGONISM PRESERVES BETA-CELL FUNCTION AND ATTENUATES ALBUMINURIA THROUGH NEPHRIN-DEPENDENT MECHANISMS

K. Thai, A. Advani, Syamantak Majumder, 2016 .

Endothelial activation and dysfunction in the pathogenesis of influenza A virus infection

Susan M. Armstrong, Warren L. Lee, Ilyse Darwish, 2013, Virulence.

Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein–Coupled Estrogen Receptor) and SR-BI (Scavenger Receptor Class B Type 1)

Michael G. Sugiyama, Warren L. Lee, S. Ghaffari, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice.

P. Loke, K. Cadwell, Sergei B Koralov, 2019, Cell host & microbe.

The CXCR 4 / CXCR 7 / SDF-1 pathway contributes to the pathogenesis of Shiga toxin – associated hemolytic uremic syndrome in humans and mice

J. Fish, C. Matouk, P. Marsden, 2011 .

Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding scavenger receptor B1

C. Beauchemin, G. Fairn, K. Fung, 2024, bioRxiv.

BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells

C. Ramírez, C. Fernández-Hernando, W. Sessa, 2020, The Journal of Biological Chemistry.

Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis.

B. Heit, A. Klip, P. Bilan, 2015, American journal of physiology. Endocrinology and metabolism.

FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses

B. Raught, G. Fairn, J. Rini, 2022, bioRxiv.

FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses

B. Raught, G. Fairn, Michael G. Sugiyama, 2020, bioRxiv.

Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation.

Xinran Liu, M. A. Lasunción, C. Ramírez, 2019, Circulation.

Inflammation Without Vascular Leakage - Science Fiction No Longer?

Warren L. Lee, N. Filewod, 2019, American journal of respiratory and critical care medicine.

Broken Barriers: A New Take on Sepsis Pathogenesis

Arthur S Slutsky, B. Steinberg, N. Goldenberg, 2011, Science Translational Medicine.

Neutrophil activation and acute lung injury

G. Downey, Warren L. Lee, 2001, Current opinion in critical care.

Interactions of Influenza and SARS-CoV-2 with the Lung Endothelium: Similarities, Differences, and Implications for Therapy

Warren L. Lee, Elyse Latreille, 2021, Viruses.

On, Around, and Through: Neutrophil-endothelial Interactions in Innate Immunity Neutrophils and Innate Immune Response

G. Downey, C. Yamashita, R. Zemans, 2022 .

Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation.

M. Cybulsky, J. Jongstra-Bilen, Clinton S. Robbins, 2021, Circulation research.

Sepsis and endothelial permeability.

Arthur S Slutsky, Warren L. Lee, Warren L Lee, 2010, The New England journal of medicine.

Role of CrkII in Fcγ Receptor-mediated Phagocytosis*

S. Grinstein, Warren L. Lee, K. Ireton, 2007, Journal of Biological Chemistry.

Phagocytosis by neutrophils.

S. Grinstein, R. Harrison, Warren L. Lee, 2003, Microbes and infection.

Development of a Zebrafish Sepsis Model for High-Throughput Drug Discovery

J. Marshall, C. D. dos Santos, A. Slutsky, 2017, Molecular medicine.

Adhesion Molecules: Master Controllers of the Circulatory System.

W. Kuebler, G. Downey, E. Schmidt, 2016, Comprehensive Physiology.

Long noncoding RNA SNHG12 integrates a DNA-PK–mediated DNA damage response and vascular senescence

P. Libby, J. Auwerx, P. Stone, 2020, Science Translational Medicine.

Translational Research in Acute Lung Injury and Pulmonary Fibrosis Thrombin stimulates albumin transcytosis in lung microvascular endothelial cells via activation of acid sphingomyelinase

M. Drab, W. Kuebler, M. Ochs, 2016 .

Thrombin stimulates albumin transcytosis in lung 1 microvascular endothelial cells via activation of 2 acid sphingomyelinase 3 4

Goldenberg, M. Drab, W. Kuebler, 2016 .

SUPPLEMENTAL DATA Cardioprotective GLP-1 metabolite prevents ischemic injury by inhibiting mitochondrial trifunctional protein-α

G. Keller, M. Wheeler, Xuetao Sun, 2022 .

A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis.

M. Cybulsky, N. Seidah, B. Heit, 2015, Cardiovascular research.

Shuttling glucose across brain microvessels, with a little help from GLUT1 and AMP kinase. Focus on "AMP kinase regulation of sugar transport in brain capillary endothelial cells during acute metabolic stress".

A. Klip, Warren L. Lee, 2012, American journal of physiology. Cell physiology.

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

B. Heit, G. Fairn, Steffen Nyegaard, 2017, Front. Physiol..

The Tangled Webs That Neutrophils Weave

S. Grinstein, Warren L. Lee, 2004, Science.

Abstract 11607: Novel Assay for Detection of LDL Transcytosis Across Coronary Endothelium Reveals an Unexpected Role for SR-B1

M. Cybulsky, B. Heit, Michael G. Sugiyama, 2014 .

Immunotherapy for Sepsis: A Good Idea or Another Dead End?

Warren L. Lee, 2018, Anesthesiology.

Quantitative analysis of membrane remodeling at the phagocytic cup.

Sergio Grinstein, S. Grinstein, D. Mason, 2007, Molecular biology of the cell.

Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells

B. Heit, A. Klip, S. Bolz, 2015, Molecular biology of the cell.

Lung Ultrasound and Microbubbles Enhance Aminoglycoside Efficacy and Delivery to the Lung in Escherichia coli-induced Pneumonia and Acute Respiratory Distress Syndrome.

W. Kuebler, L. Brochard, Michael G. Sugiyama, 2018, American journal of respiratory and critical care medicine.

Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury

A. Advani, Michael G. Sugiyama, Changsen Wang, 2015, Journal of Virology.

Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice

C. Fernández-Hernando, W. Sessa, G. Tellides, 2023, Nature Cardiovascular Research.

Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles

J. Fish, V. Torres, A. Kapus, 2023, Frontiers in Immunology.

Role of ubiquitin and proteasomes in phagosome maturation.

S. Grinstein, Warren L. Lee, A. Schreiber, 2005, Molecular biology of the cell.

Slit2 prevents neutrophil recruitment and renal ischemia-reperfusion injury.

C. Sokollik, Liping Huang, M. Puthia, 2013, Journal of the American Society of Nephrology : JASN.

Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall

J. Fish, E. Aikawa, Sasha A. Singh, 2023, bioRxiv.

LDL Transcytosis by the Arterial Endothelium—Atherosclerosis by a Thousand Cuts?

Warren L. Lee, Tse Wing Winnie Ho, Andria Henry, 2023, Current Atherosclerosis Reports.

Do viral infections mimic bacterial sepsis? The role of microvascular permeability: A review of mechanisms and methods.

B. Steinberg, N. Goldenberg, Warren L. Lee, 2012, Antiviral research.

The lung microvascular endothelium as a therapeutic target in severe influenza.

S. Mubareka, Susan M. Armstrong, Warren L. Lee, 2013, Antiviral research.

Is strengthening the endothelial barrier a therapeutic strategy for Ebola?

Warren L. Lee, N. Filewod, 2015, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

On, around, and through: neutrophil-endothelial interactions in innate immunity.

G. Downey, C. Yamashita, R. Zemans, 2011, Physiology.

A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis.

M. Cybulsky, N. Seidah, B. Heit, 2015, Cardiovascular research.

Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein–Coupled Estrogen Receptor) and SR-BI

Michael G. Sugiyama, Warren L. Lee, S. Ghaffari, 2018 .