R. Gugasyan

发表

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

A. Strasser, T. Mak, R. Hakem, 2009, Immunity.

The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia

Stefan P. Glaser, D. Vaux, G. Salvesen, 2016, Science Translational Medicine.

Independent Selection by I-A Molecules of Two Epitopes Found in Tandem in an Extended Polypeptide Antigen

I. Vidavsky, R. Gugasyan, Unanue, 2000 .

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

D. Vaux, M. Gaestel, G. Brumatti, 2016, Cancer cell.

Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF‐κB pathway

S. Gerondakis, R. Grumont, P. Tsichlis, 2011, Immunology and cell biology.

cells activated by TLR-9 signals differentiation and survival of plasmacytoid and conventional dendritic B1 and c-Rel transcription factors in the κ

S. Gerondakis, R. Grumont, H. Hochrein, 2013 .

Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction

A. Strasser, V. Dixit, S. Gerondakis, 2007, Cell Death and Differentiation.

Bcl-2 transgene expression fails to prevent fatal hepatocyte apoptosis induced by endogenous TNFα in mice lacking RelA

A. Strasser, S. Gerondakis, L. O'Reilly, 2006, Cell Death and Differentiation.

Distinct roles for the NF-kappaB1 and c-Rel transcription factors in the differentiation and survival of plasmacytoid and conventional dendritic cells activated by TLR-9 signals.

Meredith O'Keeffe, S. Gerondakis, R. Grumont, 2005, Blood.

The NF-κB transcription factor RelA is required for the tolerogenic function of Foxp3(+) regulatory T cells.

Haroon Naeem, S. Gerondakis, R. Grumont, 2016, Journal of autoimmunity.

A. Roberts, C. Quilici, T. Kitamura, 2002, The Journal of cell biology.

The NF‐κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties

A. Strasser, G. Belz, Meredith O'Keeffe, 2012, The EMBO journal.

Rel/NF‐κB transcription factors: key mediators of B‐cell activation

S. Gerondakis, M. Grossmann, Y. Nakamura, 2000 .

Rel/NF-kappaB transcription factors: key mediators of B-cell activation.

S. Gerondakis, M. Grossmann, Y. Nakamura, 2000, Immunological reviews.

C-Rel Regulates Interleukin 12 P70 Expression in Cd8+ Dendritic Cells by Specifically Inducing p35 Gene Transcription

Meredith O'Keeffe, S. Gerondakis, R. Grumont, 2001, The Journal of experimental medicine.

Unravelling the complexities of the NF-κB signalling pathway using mouse knockout and transgenic models

S. Gerondakis, R. Grumont, A. Banerjee, 2006, Oncogene.

The Transcription Factors c-rel and RelA Control Epidermal Development and Homeostasis in Embryonic and Adult Skin via Distinct Mechanisms

George Varigos, Tim Thomas, George Grigoriadis, 2004, Molecular and Cellular Biology.

The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

D. Baltimore, A. Strasser, S. Gerondakis, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells.

S. Nutt, A. Voss, T. Thomas, 2006, Genes & development.

Loss of NF‐&kgr;B1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT‐1‐Dependent Manner

M. Christie, A. Strasser, G. Smyth, 2018, Immunity.

The anti‐apoptotic activities of Rel and RelA required during B‐cell maturation involve the regulation of Bcl‐2 expression

Steve Gerondakis, A. Strasser, Jerry M. Adams, 2000, The EMBO journal.

cells by neutralizing Bim via distinct mechanisms B1 and c-Rel cooperate to promote the survival of TLR4-activated B κ NF-

A. Strasser, R. Grumont, C. White, 2012 .

NF-kappaB1 and c-Rel cooperate to promote the survival of TLR4-activated B cells by neutralizing Bim via distinct mechanisms.

A. Strasser, S. Gerondakis, R. Grumont, 2008, Blood.

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

R. Cone, P. Ramsland, R. Gugasyan, 2015, Front. Physiol..

Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition

D. Anderson, R. Cone, R. Gugasyan, 2017, Mucosal Immunology.

c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells

M. F. Shannon, Karen L. Bunting, Li Wu, 2009, The Journal of experimental medicine.

NF‐κB subunit specificity in hemopoiesis

S. Gerondakis, R. Grumont, T. Sidwell, 2012, Immunological reviews.

The Role of NFκB in T-lymphocyte Development and Function

S. Berzins, R. Gugasyan, L. K. Lie, 2012 .

Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells.

Steve Gerondakis, M. McMahon, S. Gerondakis, 2006, Proceedings of the National Academy of Sciences of the United States of America.

c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells

M. F. Shannon, Karen L. Bunting, Li Wu, 2010, The Journal of Experimental Medicine.

Dendritic Cells by Specifically Inducing p 35 Gene Transcription

S. Gerondakis, R. Grumont, C. White, 2001 .

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

A. Strasser, M. Febbraio, K. Fairfax, 2016, The Journal of experimental medicine.

Isolation and quantitation of a minor determinant of hen egg white lysozyme bound to I-Ak by using peptide-specific immunoaffinity.

E. Unanue, C. Nelson, I. Vidavsky, 1998, Journal of immunology.

Immunoaffinity by Using Peptide-Specific k Bound to I-A Determinant of Hen Egg White Lysozyme Isolation and Quantitation of a Minor

E. Unanue, C. Nelson, I. Vidavsky, 1998 .

Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota

R. Gugasyan, Joshua A. Hayward, G. Tachedjian, 2020, Frontiers in Cellular and Infection Microbiology.

Prevention of splenic granuloma formation in adjuvant arthritis by 2-acetyl-4-tetrahydroxybutylimidazole (THI).

T. Mandel, R. Gugasyan, I. Wicks, 1997, Immunology letters.

The effect of 2-acetyl-4-tetrahydroxybutylimidazole on lymphocyte subsets during a contact hypersensitivity response in the NOD mouse.

T. Mandel, R. Gugasyan, C. Losinno, 1995, Immunology letters.

Independent Selection by I-Ak Molecules of Two Epitopes Found in Tandem in an Extended Polypeptide Antigen1

E. Unanue, I. Vidavsky, K. van der Drift, 2000, The Journal of Immunology.

Extended Polypeptide Antigen Two Epitopes Found in Tandem in an Molecules ofkIndependent Selection

Koen van der Drift, E. Unanue, I. Vidavsky, 2000 .

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

A. Strasser, T. Mak, R. Hakem, 2009, Immunity.

Correction: Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics (Cancer Cell (2016) 30(3) (499–500) (S1535610816000350) (10.1016/j.ccell.2016.01.006))

Stefan P. Glaser, D. Vaux, M. Gaestel, 2016 .

Emigration of mature T cells from the thymus is inhibited by the imidazole‐based compound 2‐acetyl‐4‐tetrahydroxybutylimidazole

R. Scollay, R. Gugasyan, Shortman, 1998, Immunology.