K. Carson

发表

Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8).

C. Zhang, S. Ghosh, B. Jaffee, 2006, Journal of medicinal chemistry.

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).

B. D. Harris, Ahmed F. Abdel-Magid, Cynthia A. Maryanoff, 1996, The Journal of organic chemistry.

LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders.

Alan G. E. Wilson, D. Augeri, S. D. Kimball, 2009, Journal of medicinal chemistry.

LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2015, Pharmacology research & perspectives.

Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth.

B. Ganem, A. Abe, N. Radin, 1995, Journal of lipid research.

Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.

Alan G. E. Wilson, Vijay T. Ahuja, Y. Liu, 2015, Bioorganic & medicinal chemistry letters.

Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors.

Alan G. E. Wilson, M. Shen, T. Stouch, 2009, Bioorganic & medicinal chemistry letters.

Small molecule antagonists of the CC chemokine receptor 4 (CCR4).

B. Jaffee, T. Ocain, J. Gonzalo, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-molecule antagonists for interleukin-8 receptor.

D. T. Connor, B. Roth, S. Qin, 2003, Bioorganic & medicinal chemistry.

Inhibition of sphingosine 1-phosphate lyase for the treatment of rheumatoid arthritis: discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime (LX2931) and (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932).

Alan G. E. Wilson, W. K. Sonnenburg, D. Augeri, 2010, Journal of medicinal chemistry.

Reductive amination of aldehydes and ketones by using sodium triacetoxyborohydride

A. Abdel-Magid, C. Maryanoff, K. Carson, 1990 .

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures.

B. D. Harris, A. Abdel-Magid, C. Maryanoff, 1996 .

Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase

B. Ganem, N. Radin, J. Shayman, 1994 .

4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase.

Alan G. E. Wilson, J. Tarver, J. Barbosa, 2016, Bioorganic & medicinal chemistry letters.

Reductive Amination of Aldehydes and Ketones by Using Sodium Triacetoxyborohydride.

A. Abdel-Magid, C. Maryanoff, K. Carson, 1991 .

Discovery of PqsE Thioesterase Inhibitors for Pseudomonas aeruginosa using DNA-Encoded Small Molecule Library Screening.

M. Tota, Julie S. Valastyan, B. Bassler, 2019, ACS chemical biology.

Sulfonopeptide inhibitors of leukocyte adhesion

K. Carson, M. Briskin, N. Cochran, 1997 .

5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase.

Alan G. E. Wilson, M. Shen, D. Augeri, 2009, Bioorganic & medicinal chemistry letters.

Novel Potent Inhibitors of Deoxycytidine Kinase Identified and Compared by Multiple Assays

S. Patel, M. Miranda, Xuan-Chuan. Yu, 2010, Journal of biomolecular screening.

Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain

Alan G. E. Wilson, G. Shankar, S. Mandlekar, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Chapter 17. Chemokines: Targets for novel therapeutics

G. Larosa, K. Carson, B. K. Trivedi, 2000 .

Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity

Alan G. E. Wilson, Wei-Chun Chang, D. Augeri, 2014, PloS one.

Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.

Alan G. E. Wilson, N. C. Goodwin, F. Mseeh, 2017, Journal of medicinal chemistry.

Genetic and Chemical Inhibition of Sphingosine 1-Phosphate Lyase Results in Peripheral Lymphopenia and Alleviates Disease Development in Animal Models of Inflammation and Autoimmunity.

S. Anderson, D. Augeri, S. D. Kimball, 2007 .

Curtius rearrangement in the 5-phenyl-1,4-benzodiazepine series. Unprecedented participation by an imine nitrogen

M. Bock, R. M. Dipardo, R. Freidinger, 1990 .

Curtius Rearrangement in the 5-Phenyl-1,4-benzodiazepine Series. Unprecedented Participation by an Imine Nitrogen.

M. Bock, R. M. Dipardo, R. Freidinger, 1990 .

Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase.

Alan G. E. Wilson, J. Tarver, J. Barbosa, 2016, Bioorganic & medicinal chemistry letters.

Inhibition of AAK 1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain s

Alan G. E. Wilson, Malley, G. Shankar, 2016 .

Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.

Alan G. E. Wilson, Vijay T. Ahuja, Y. Liu, 2015, Bioorganic & medicinal chemistry letters.

Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders.

Alan G. E. Wilson, D. Augeri, J. Tarver, 2009, Journal of medicinal chemistry.