P. Raubo

发表

1-Phenyl-8-azabicyclo[3.2.1]octane ethers: a novel series of neurokinin (NK1) antagonists.

Alan Wheeldon, Clare London, Piotr Raubo, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and structure of oxetane containing tripeptide motifs.

Nathaniel G. Martin, N. H. Powell, R. Notman, 2014, Chemical communications.

Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.

M. Beer, J. Stanton, I. Huscroft, 2006, Bioorganic & medicinal chemistry letters.

The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1

A. Nyström, M. Någård, M. S. Winzell, 2017, PloS one.

Development of a novel BCL6 PROTAC to provide insight into small molecule targeting of BCL6

David M. Wilson, Qing Cao, M. Waring, 2018 .

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.

David M. Wilson, Qing Cao, M. Waring, 2018, ACS chemical biology.

Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors.

Matthew Grist, C. Chuaqui, Qing Cao, 2017, Journal of medicinal chemistry.

Development of a stepwise [3 + 3] annelation to functionalized piperidines.

J. P. Harrity, P. Raubo, K. M. Goodenough, 2005, Organic letters.

Sarcosine based indandione hGlyT1 inhibitors.

S. Fletcher, I. Huscroft, P. Raubo, 2006, Bioorganic & medicinal chemistry letters.

The discovery and evaluation of 3-amino-2(1H)-pyrazinones as a novel series of selective p38α MAP kinase inhibitors.

P. Raubo, P. Willis, R. Evans, 2020, Bioorganic & medicinal chemistry letters.

Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy.

A. Bailey, Robert D. M. Davies, Alastair J. H. Brown, 2017, Journal of medicinal chemistry.

An iron-catalysed C–C bond-forming spirocyclization cascade providing sustainable access to new 3D heterocyclic frameworks

L. Brown, J. Birkett, J. Sweeney, 2016, Nature Chemistry.

Solid-Phase Synthesis of Oxetane Modified Peptides.

M. Shipman, Astrid Knuhtsen, P. Raubo, 2017, Organic letters.

Tandem Transformations Initiated by the Migration of a Silyl Group. Some New Synthetic Applications of Silyloxiranes

P. Jankowski, P. Raubo, J. Wicha, 1995 .

Synthesis of Oxetane- and Azetidine-Containing Spirocycles Related to the 2,5-Diketopiperazine Framework

N. H. Powell, G. Clarkson, M. Shipman, 2015 .

Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts.

J. P. Harrity, P. Raubo, Anne-Chloé M. A. Nassoy, 2015, Chemical communications.

Discovery of a Thiadiazole-Pyridazine Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.

Mairi M. Littleson, Peter D Smith, Peng-Fei Wang, 2019, Journal of medicinal chemistry.

Synthesis and cycloaddition chemistry of oxetanyl-substituted sydnones

J. P. Harrity, P. Raubo, Anne-Chloé M. A. Nassoy, 2013 .

A concise asymmetric route to Nuphar alkaloids. A formal synthesis of (-)-deoxynupharidine.

J. P. Harrity, P. Raubo, W. Moran, 2003, Organic letters.

Development of a flexible approach to Nuphar alkaloids via two enantiospecific piperidine-forming reactions.

J. P. Harrity, P. Raubo, W. Moran, 2005, The Journal of organic chemistry.

A mechanistic study of the Lewis base-directed cycloaddition of 2-pyrones and alkynylboranes.

A. Meijer, J. P. Harrity, P. Raubo, 2014, Journal of the American Chemical Society.

1-Phenyl-8-azabicyclo[3.2.1]octane ethers: a novel series of neurokinin (NK1) antagonists.

Alan Wheeldon, Clare London, Piotr Raubo, 2006, Bioorganic & medicinal chemistry letters.

Synthesis of the glycidol (1R,2R)-1-iodo-2-(triphenylsilyloxy)cyclopropane: new rearrangements of 2,3-epoxy-3-(trialkyl/arylsilyl)-propan-1-ols

P. Raubo, J. Wicha, B. Achmatowicz, 1995 .

Synthesis of 4H-Pyrazino[1,2-a]pyrimidine-4,9(8H)-diones and Imidazo[1,2-a]pyrazin-8(7H)-ones

P. Raubo, N. Ladwa, 2012 .

Oxidation of an αβ-(epoxyalkyl)trimethylsilane with pyridine oxides in the presence of silylating agents. A facile enantioselective synthesis of glyceraldehyde derivatives

P. Raubo, J. Wicha, 1994 .

An iterative synthesis of optically-active 1,2-diols using α,β-epoxysilanes as key intermediates

P. Raubo, J. Wicha, 1996 .

Synthetic studies on the pederin family of antitumour agents. Syntheses of mycalamide B, theopederin D and pederin

R. Narquizian, L. Farrugia, P. Kocieňski, 2000 .

A synthesis of 18-O-methyl mycalamide B

Justin K Davis, D. Davies, P. Kocieňski, 1996 .

The in vitro biological activities of synthetic 18-O-methyl mycalamide B, 10-epi-18-O-methyl mycalamide B and pederin.

D. Davies, P. Kocieňski, P. Raubo, 1997, Anti-cancer drug design.

Optically active acylsilanes. Synthesis of selected 2,3-O-isopropylidene-1-(trialkyl/arylsilyl)glyceraldehyde derivatives

P. Raubo, J. Wicha, 1995 .

Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRASG12C.

Doyle J Cassar, Nichola L. Davies, J. Breed, 2022, Journal of medicinal chemistry.

Enantioselective Silicon-Mediated Synthesis of Glyceraldehyde Derivatives from Propargyl Alcohol

P. Raubo, J. Wicha, 1993 .

Synthesis of Optically Active 2,3-O-Isopropylidene-1-(trimethylsilyl)glyceraldehyde and Other Derivatives of (.alpha.-Hydroxyacyl)silane

P. Raubo, J. Wicha, 1994 .

Development of oxetane modified building blocks for peptide synthesis.

G. Clarkson, M. Shipman, P. Raubo, 2020, Organic & biomolecular chemistry.

Free Ligand 1D NMR Conformational Signatures to Enhance Structure Based Drug Design of a Mcl-1 inhibitor (AZD5991) and other Synthetic Macrocycles.

Nichola L. Davies, E. Chiarparin, M. Lamb, 2019, Journal of medicinal chemistry.

Impact of oxetane incorporation on the structure and stability of alpha-helical peptides.

R. Notman, M. Shipman, P. Raubo, 2020, Physical chemistry chemical physics : PCCP.

Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α- but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation.

M. Waring, D. M. Andrews, R. Rowlinson, 2014, Chemical Communications.

Discovery of potent, selective small molecule inhibitors of α-subtype of type III phosphatidylinositol-4-kinase (PI4KIIIα).

M. Waring, D. M. Andrews, G. Robb, 2015, Bioorganic & medicinal chemistry letters.

Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration.

Doyle J Cassar, Nichola L. Davies, J. Breed, 2023, Journal of medicinal chemistry.

Enzymatically-stable oxetane-based dipeptide hydrogels.

D. Adams, Emily R. Draper, M. Shipman, 2018, Chemical communications.

Synthesis of four stereoisomeric tetrose derivatives from propargyl alcohol. One-carbon homologation of vinylsilanes via .alpha.,.beta.-epoxy silanes

P. Raubo, J. Wicha, B. Achmatowicz, 1992 .

Achieving improved permeability by hydrogen bond donor modulation in a series of MGAT2 inhibitors

Philip A. MacFaul, Graeme R. Robb, Andrew G. Leach, 2013 .

Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts.

P. Raubo, Anne-Chloé M. A. Nassoy, J. Harrity, 2015, Chemical communications.