A. Wheeldon

发表

1-Phenyl-8-azabicyclo[3.2.1]octane ethers: a novel series of neurokinin (NK1) antagonists.

Alan Wheeldon, Clare London, Piotr Raubo, 2006, Bioorganic & medicinal chemistry letters.

Hoe 140 and pseudo-irreversible antagonism in the rat vas deferens in vitro.

R. A. Coleman, D. McQueen, C. Bountra, 2000, European journal of pharmacology.

Evidence of a role for GTP cyclohydrolase‐1 in visceral pain

C. Mein, C. Knowles, D. Bulmer, 2015, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Characterization of the inhibitory prostanoid receptors on human neutrophils

A. Wheeldon, C. Vardey, 1993, British journal of pharmacology.

CHARACTERIZATION OF THE RECEPTOR MEDIATING THE ANTI‐ANAPHYLACTIC EFFECTS OF β‐ADRENOCEPTOR AGONISTS IN HUMAN LUNG TISSUE in vitro

A. Wheeldon, P. Butchers, C. Vardey, 1980, British journal of pharmacology.

Predicting behaviour and learning problems at school entry: Examining the utility of a parent-, teacher-, and a child-based scale

A. Wheeldon, J. Reddington, J. Reddington, 2009 .

Behavioral and Neurochemical Alterations in Mice Deficient in Anaplastic Lymphoma Kinase Suggest Therapeutic Potential for Psychiatric Indications

Petr Znamenskiy, P. Whiting, J. Bilsland, 2008, Neuropsychopharmacology.

Fused tricyclic pyrrolizinones that exhibit pseudo-irreversible blockade of the NK1 receptor.

S. Boyce, R. DeVita, J. Demartino, 2010, Bioorganic & medicinal chemistry letters.

Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK1 antagonists.

P. Davies, S. Boyce, M. Reibarkh, 2010, Bioorganic & medicinal chemistry letters.

Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists.

S. Boyce, R. DeVita, J. Demartino, 2008, Bioorganic & medicinal chemistry.

Pyrrolidine-carboxamides and oxadiazoles as potent hNK1 antagonists.

R. DeVita, K. Tsao, S. Mills, 2007, Bioorganic & medicinal chemistry letters.

Demonstration of functional neuronal beta3-adrenoceptors within the enteric nervous system.

G. Sanger, M. Schemann, Kevin Lee, 2007, Gastroenterology.

The discovery of potent, selective, and orally bioavailable hNK1 antagonists derived from pyrrolidine.

R. DeVita, H. Burns, R. Hargreaves, 2007, Bioorganic & medicinal chemistry letters.

The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia

M. Trevethick, A. Wheeldon, M. Trevethick, 1997, Neuroscience.

Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist.

M. Bock, R. M. Dipardo, R. Chang, 2005, European journal of pharmacology.

Improving human computer interaction in intelligent tutoring systems

Alan Wheeldon, A. Wheeldon, 2007 .

1-Phenyl-8-azabicyclo[3.2.1]octane ethers: a novel series of neurokinin (NK1) antagonists.

Alan Wheeldon, Clare London, Piotr Raubo, 2006, Bioorganic & medicinal chemistry letters.

Tetrahydroindolizinone NK1 antagonists.

R. DeVita, K. Tsao, G. Morriello, 2010, Bioorganic & medicinal chemistry letters.

NK1 antagonists based on seven membered lactam scaffolds.

Alan Wheeldon, Maria Dominguez, U. Gerhard, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of 8-azabicyclo[3.2.1]octane benzylamine NK1 antagonists.

Alan Wheeldon, K. Tsao, C. Swain, 2006, Bioorganic & medicinal chemistry letters.

Comparison of the phenotype of NK1R−/− mice with pharmacological blockade of the substance P (NK 1 ) receptor in assays for antidepressant and anxiolytic drugs

S. Hunt, R. Porsolt, C. de Felipe, 2001, Behavioural pharmacology.

Pharmacological blockade or genetic deletion of substance P (NK1) receptors attenuates neonatal vocalisation in guinea-pigs and mice

A. Wheeldon, T Harrison, E. Seward, 2000, Neuropharmacology.

Validation of the dual channel weight averager as an instrument of the measurement of clinically relevant pain

S. Thompson, Alan Wheeldon, Nick M. Clayton, 1997 .

Functional characterization of three adenosine receptor types

P. Strong, A. Wheeldon, J. Coates, 1993, British journal of pharmacology.

A COMPARISON OF THE ANTI‐ANAPHYLACTIC ACTIVITIES OF SALBUTAMOL AND DISODIUM CROMOGLYCATE IN THE RAT, THE RAT MAST CELL AND IN HUMAN LUNG TISSUE

J. Fullarton, L. E. Thompson, A. Wheeldon, 1979, British journal of pharmacology.

A rapid method for the quantification of mouse hippocampal neurogenesis in vivo by flow cytometry Validation with conventional and enhanced immunohistochemical methods

J. Bilsland, G. Mcallister, F. Murray, 2006, Journal of Neuroscience Methods.

Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists.

R. DeVita, R. Hargreaves, K. Tsao, 2009, Journal of medicinal chemistry.

Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurones in the locus coeruleus

K. Maubach, G. Seabrook, G. Chicchi, 2002, Neuroscience.

UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms.

G. P. Livi, G. Sanger, A. Abuin, 2009, American journal of physiology. Gastrointestinal and liver physiology.

The substance P antagonist L-760,735 inhibits stress-induced NK1 receptor internalisation in the basolateral amygdala

D. Smith, David W. Smith, A. Wheeldon, 1999, Brain Research.

Calcium antagonists in exercise-induced asthma.

A. Wheeldon, P. Butchers, C. Vardey, 1981, British medical journal.

Generating Explanations using an Automated Planner and Modeling Reasoning Processes, Skills and Knowledge

Jim Reye, Alan Wheeldon, J. Reye, 2007, ExaCt.

Histamine-containing cells from bronchial lavage of macaque monkeys. Time course and inhibition of anaphylactic histamine release.

A. Wheeldon, P. Butchers, C. Vardey, 1980, International archives of allergy and applied immunology.

UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms.

G. P. Livi, G. Sanger, A. Abuin, 2009, American journal of physiology. Gastrointestinal and liver physiology.