Tomohiko Taniguchi

发表

A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes.

Yasunari Kanda, Takashi Yoshinaga, Kohei Sawada, 2017, Journal of pharmacological and toxicological methods.

CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia--effects of 7 reference compounds at 10 facilities.

Ikumi Washio, Emi Matsumoto, Shigekazu Shimizu, 2016, Journal of pharmacological and toxicological methods.

CSAHi study: Detection of drug-induced ion channel/receptor responses, QT prolongation, and arrhythmia using multi-electrode arrays in combination with human induced pluripotent stem cell-derived cardiomyocytes.

Masao Oguchi, Hiroyuki Ando, Wataru R. Yamamoto, 2017, Journal of pharmacological and toxicological methods.

Appraisal of state-ofthe-art Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes

Y. Sekino, K. Sawada, Tomoharu Osada, 2015 .

A novel method of selecting human embryonic stem cell-derived cardiomyocyte clusters for assessment of potential to influence QT interval.

N. Kohmura, K. Sawada, T. Yoshinaga, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Probucol and the cholesterol synthesis inhibitors simvastatin and triparanol regulate I ks channel function differently

K. Sawada, T. Yoshinaga, Tomohiko Taniguchi, 2013, Human & experimental toxicology.

Use of Human Embryonic Stem Cell-Derived Cardiomyocyte Clusters to Assess Potential for Chronic Treatment with Compounds to Cause QT Prolongation

K. Sawada, T. Yoshinaga, K. Yamazaki, 2014 .

Beat-to-Beat Variability in Field Potential Duration in Human Embryonic Stem Cell-Derived Cardiomyocyte Clusters for Assessment of Arrhythmogenic Risk, and a Case Study of Its Application

K. Sawada, T. Yoshinaga, K. Yamazaki, 2014 .

Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes.

Yasunari Kanda, Atsuhiro Yamanishi, Etsushi Takahashi, 2018, Journal of pharmacological sciences.

Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes.

Yasunari Kanda, Kohei Sawada, Seiji Hayashi, 2015, Journal of pharmacological and toxicological methods.

Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential

Y. Sekino, K. Sawada, T. Yoshinaga, 2016, PloS one.

Low-density plating is sufficient to induce cardiac hypertrophy and electrical remodeling in highly purified human iPS cell-derived cardiomyocytes.

K. Sawada, M. Uesugi, Tomohiko Taniguchi, 2014, Journal of pharmacological and toxicological methods.

Chronic Probucol Treatment Decreases the Slow Component of the Delayed-Rectifier Potassium Current in CHO Cells Transfected With KCNQ1 and KCNE1: A Novel Mechanism of QT Prolongation

K. Sawada, T. Yoshinaga, Tomohiko Taniguchi, 2012, Journal of cardiovascular pharmacology.