H. Fu

发表

Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety.

Yaoquan Liu, W. Crumb, D. Hardy, 2009, Journal of medicinal chemistry.

On the Mechanism of Action of 9-O-Arylalkyloxime Derivatives of 6-O-Mycaminosyltylonolide, a New Class of 16-Membered Macrolide Antibiotics

Daniel N. Wilson, G. Dinos, L. Katz, 2006, Molecular Pharmacology.

Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides.

L. Katz, D. Myles, H. Fu, 2006, Bioorganic & Medicinal Chemistry Letters.

Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts.

L. Katz, S. D. Dong, Shannon L. Ward, 2004, Chemistry & biology.

Residues of 14-3-3 zeta required for activation of exoenzyme S of Pseudomonas aeruginosa.

S. Masters, J. Barbieri, L. Zhang, 1999, Biochemistry.

Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor.

C. Khosla, D. Hopwood, H. Fu, 1994, Chemistry & biology.

Interaction of 14-3-3 with a nonphosphorylated protein ligand, exoenzyme S of Pseudomonas aeruginosa.

S. Masters, Lixin Zhang, J. Barbieri, 1999, Biochemistry.

Preparation of Erythromycin Analogs Having Functional Groups at C-15

K. Bush, G. Ashley, M. Macielag, 2006, The Journal of Antibiotics.

Coupled cell morphology investigation and metabolomics analysis improves rapamycin production in Streptomyces hygroscopicus

X. Jia, Haishan Qi, J. Wen, 2014 .

Attenuated Listeria monocytogenes, a Mycobacterium tuberculosis ESAT-6 antigen expression and delivery vector for inducing an immune response.

D. Tian, X. Jiao, Yuelan Yin, 2012, Research in microbiology.

Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase.

C. Khosla, D. Hopwood, R. Mcdaniel, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A novel Cd(II) complex with 1,3-bis(4-Pyridyl)propane: Synthesis, crystal structure, and interaction with DNA

E. Gao, Mingchang Zhu, H. Fu, 2014, Russian Journal of Coordination Chemistry.

Survival-promoting functions of 14-3-3 proteins.

S. Masters, R. Subramanian, H. Zhang, 2001, Biochemical Society transactions.

Synthesis, crystal structure, solid-state fluorescence, and interaction with DNA of mononuclear La(III) complex: La(Phen)2L2(NO3)

E. Gao, Mingchang Zhu, H. Fu, 2014 .

Structure-based design of selective inhibitors of dihydrofolate reductase: synthesis and antiparasitic activity of 2, 4-diaminopteridine analogues with a bridged diarylamine side chain.

V. Cody, S F Queener, A Rosowsky, 1999, Journal of medicinal chemistry.

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

C. Gustafsson, C. Gustafsson, G. Ashley, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Enhancement of ascomycin production in Streptomyces hygroscopicus var. ascomyceticus by combining resin HP20 addition and metabolic profiling analysis

X. Jia, Haishan Qi, J. Wen, 2014, Journal of Industrial Microbiology & Biotechnology.

Prophylactic and therapeutic efficacy of an attenuated Listeria monocytogenes-based vaccine delivering HPV16 E7 in a mouse model.

Z. Pan, X. Jiao, Maozhi Hu, 2012, International journal of molecular medicine.

Chemistry and biology of macrolide antiparasitic agents.

J. Boothroyd, C. Khosla, W. Roush, 2011, Journal of medicinal chemistry.

Engineered Biosynthesis of Novel Polyketides: Properties of the whiE Aromatase/Cyclase

J. Bailey, C. Khosla, D. Hopwood, 1996, Nature Biotechnology.

Engineered biosynthesis of novel polyketides: regiospecific methylation of an unnatural substrate by the tcmO O-methyltransferase.

J. Bailey, C. Khosla, M. Álvarez, 1996, Biochemistry.

Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display.

E Ruoslahti, Y C Liu, E. Ruoslahti, 1999, Biochemistry.

Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.

C. Khosla, C. Méndez, J. Salas, 1996, Chemistry & biology.

Engineered biosynthesis of novel polyketides: stereochemical course of two reactions catalyzed by a polyketide synthase.

C. Khosla, D. Hopwood, R. Mcdaniel, 1994, Biochemistry.

Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.

D. Cane, C. Khosla, H Fu, 1999, Biochemistry.

Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase.

R. Mcdaniel, H. Fu, M. Betlach, 1999, Chemistry & biology.

Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae

Leonard Katz, L. Katz, Shannon L. Ward, 2004, Applied Microbiology and Biotechnology.

Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases.

R McDaniel, R. Mcdaniel, H Fu, 2000, Chemistry & biology.

An FKBP12 binding assay based upon biotinylated FKBP12.

D. Santi, H. Fu, C. Carreras, 2001, Analytical biochemistry.

Antibiotic activity of polyketide products derived from combinatorial biosynthesis: Implications for directed evolution

Chaitan Khosla, C. Khosla, Hong Fu, 1996, Molecular Diversity.

Prophylactic and therapeutic efficacy of an attenuated Listeria monocytogenes-based vaccine delivering HPV16 E7 in a mouse model.

Z. Pan, X. Jiao, Maozhi Hu, 2012, International journal of molecular medicine.