Derek Lee

发表

Long non-coding RNA expression profiles predict clinical phenotypes in glioma

Anderson Chun On Tsang, Xiaoqin Zhang, Xiaoqin Zhang, 2012, Neurobiology of Disease.

CELL BIOLOGY AND SIGNALING

V. P. Collins, Michael A. Koldobskiy, R. Spang, 2010 .

Chemoresistance in Glioma

G. Leung, Stella Sun, Derek Lee, 2013 .

Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide

G. Leung, N. Lee, W. Lui, 2012, Journal of Neuro-Oncology.

Comparison between self‐assembling peptide nanofiber scaffold (SAPNS) and fibrin sealant in neurosurgical hemostasis

Xiaoqin Zhang, G. Leung, W. Lui, 2015, Clinical and translational science.

Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer

I. Ng, C. C. Wong, Lai Wei, 2021, Communications Biology.

The folate cycle is a new metabolic weakness of cancer

C. C. Wong, Derek Lee, 2017, Molecular & cellular oncology.

Metabolic management of microenvironment acidity in glioblastoma

C. Chinopoulos, M. Kiebish, T. Seyfried, 2022, Frontiers in Oncology.

Effects of progesterone vs. dexamethasone on brain oedema and inflammatory responses following experimental brain resection

Xiaoqin Zhang, E. Wu, G. Leung, 2014, Brain injury.

Commercial Stevia does not inhibit growth or biofilm formation of Escherichia coli strain MG1655

Derek Lee, A. R. Hossain, Thomas Soroski, 2020 .

Genome‐Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment

C. C. Wong, Aki Pui-Wah Tse, Derek Lee, 2022, Advanced science.

CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma

D. Cescon, P. Khong, I. Ng, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition

Xiaoqin Zhang, G. Leung, Stella Sun, 2017, Journal of Neuro-Oncology.

Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses.

Yan Zhang, C. C. Wong, D. K. Chiu, 2022, Journal of hepatology.

Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species

I. Ng, C. C. Wong, F. H. Tsang, 2021, Hepatology.

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

I. Ng, C. C. Wong, F. H. Tsang, 2019, Nature Communications.

Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer.

I. Ng, C. C. Wong, Lai Wei, 2021, Cell reports.

IDH1 mutation-associated long non-coding RNA expression profile changes in glioma

Xiaoqin Zhang, G. Leung, W. Lui, 2015, Journal of Neuro-Oncology.

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma

S. Lowe, I. Ng, C. C. Wong, 2019, Hepatology.

Inhibition of CMTM4 Sensitizes Cholangiocarcinoma and Hepatocellular Carcinoma to T Cell–Mediated Antitumor Immunity Through PD‐L1

I. Ng, C. C. Wong, D. K. Chiu, 2021, Hepatology communications.

EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY

Tina N. Davis, Forrest M Kievit, Atique U. Ahmed, 2013 .

Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression

I. Ng, C. C. Wong, F. H. Tsang, 2019, Gut.

Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer

I. Ng, C. C. Wong, F. H. Tsang, 2018, Oncogenesis.

Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma

I. Ng, C. C. Wong, F. H. Tsang, 2017, The Journal of clinical investigation.

Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26

I. Ng, C. C. Wong, D. K. Chiu, 2016, Hepatology.

Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway

Huafeng Zhang, Irene Oi-Lin Ng, Derek Lee, 2019, Cell Death & Disease.

Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling

P. Day, K. Man, G. Leung, 2017, Oncotarget.

Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling

P. Day, K. Man, G. Leung, 2017, Oncotarget.

Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

I. Ng, C. C. Wong, D. K. Chiu, 2022, Nature communications.

Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

I. Ng, C. C. Wong, D. K. Chiu, 2022, Nature Communications.

Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways.

P. Day, G. Leung, N. Lee, 2013, Neuro-oncology.

Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response.

G. Leung, Stella Sun, Derek Lee, 2014, Anticancer research.

Polo‐like kinase 4 inhibitor CFI‐400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity

D. Cescon, T. Mak, P. Khong, 2022, Hepatology.

NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma

I. Ng, C. C. Wong, M. Wong, 2016, Clinical Cancer Research.

Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer

I. Ng, C. C. Wong, C. Goh, 2023, Cellular and molecular gastroenterology and hepatology.

MicroRNA-210 and Endoplasmic Reticulum Chaperones in the Regulation of Chemoresistance in Glioblastoma

G. Leung, W. Lui, Stella Sun, 2015, Journal of Cancer.

Title Folate cycle enzyme MTHFD 1 L confers metabolic advantages inhepatocellular carcinoma

I. Ng, C. C. Wong, Derek Lee, 2022 .

NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma

I. Ng, C. C. Wong, M. Wong, 2016, Clinical Cancer Research.