M. Handler

发表

Cytogenetics in pediatric low-grade astrocytomas.

L. Mcgavran, N. Foreman, J. Fleitz, 2002, Medical and pediatric oncology.

Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.

Austin E. Gillen, Eric W Prince, J. Hesselberth, 2020, Cell reports.

Magnetic resonance-guided stereotactic laser ablation therapy for the treatment of pediatric brain tumors: a multiinstitutional retrospective study.

M. Smyth, D. Couture, S. Huckins, 2020, Journal of neurosurgery. Pediatrics.

Chiari I Malformation Associated with Syringomyelia and Scoliosis: A Twenty-Year Review of Surgical and Nonsurgical Treatment in a Pediatric Population

M. O’Brien, M. Handler, M. Erickson, 2002, Spine.

The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.

R. Rauch, M. Dishop, Marcos de Almeida, 2016, Clinical Infectious Diseases.

Insular epilepsy surgery

J. Ojemann, M. Handler, P. Laoprasert, 2017, Epilepsia.

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors.

A. Thorburn, D. Mirsky, V. Amani, 2014, Cancer discovery.

Neoplastic and immune single cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma

J. Hesselberth, M. Sill, R. Wechsler-Reya, 2020, bioRxiv.

Limited utility despite accuracy of the national SEER dataset for the study of craniopharyngioma

B. Beaty, N. Foreman, B. O’neill, 2012, Journal of Neuro-Oncology.

Incidence of seizures on continuous EEG monitoring following traumatic brain injury in children.

K. Chapman, Suhong Tong, B. O’neill, 2015, Journal of neurosurgery. Pediatrics.

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma

M. Remke, Michael D. Taylor, V. Amani, 2014, Oncotarget.

Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas.

A. Donson, N. Foreman, P. Jedlicka, 2012, Journal of neurosurgery. Pediatrics.

Intracranial Ewing sarcoma: four pediatric examples

B. Kleinschmidt-DeMasters, J. Madden, N. Foreman, 2017, Child's Nervous System.

MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma

A. Donson, N. Foreman, M. Handler, 2007, Pediatric blood & cancer.

NF-&kgr;B upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma

Kenneth L. Jones, R. Vibhakar, A. Donson, 2017, Neuro-oncology.

Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.

Eric W Prince, Kenneth L. Jones, S. Karam, 2019, Neuro-oncology.

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

Michael D. Taylor, A. Dubuc, R. Vibhakar, 2012, BMC Cancer.

Surgery for infants with catastrophic epilepsy: an analysis of complications and efficacy

K. Knupp, B. O’neill, M. Handler, 2015, Child's Nervous System.

A proteomic analysis of pediatric seizure cases associated with astrocytic inclusions

L. Hazrati, H. Otsubo, J. Rutka, 2012, Epilepsia.

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

V. Amani, R. Vibhakar, A. Donson, 2016, BMC Cancer.

Frontal and occipital horn ratio is associated with multifocal intraparenchymal hemorrhages in neonatal shunted hydrocephalus.

N. Stence, D. Mirsky, Jonathon J Parker, 2017, Journal of neurosurgery. Pediatrics.

Pediatric versus adult meningioma: comparison of epidemiology, treatments, and outcomes using the Surveillance, Epidemiology, and End Results database

B. Beland, R. Dudley, Arthur K Liu, 2018, Journal of Neuro-Oncology.

Fractionated stereotactic radiosurgery for recurrent ependymoma in children

N. Stence, R. Vibhakar, N. Foreman, 2013, Journal of Neuro-Oncology.

Aortocoronary Saphenous Vein Bypass Grafts: Long-term Patency, Morphology and Blood Flow in Patients with Patent Grafts Early After Surgery

R. Hamby, A. Aintablian, G. Wisoff, 1979, Circulation.

Severe thrombocytopenia as a result of contrast left ventricular angiography.

M. Handler, K. Chadda, P. Wein, 1982, Catheterization and cardiovascular diagnosis.

Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas

C. Hawkins, K. Davies, D. Aisner, 2020, Neuro-oncology advances.

Maintaining Outstanding Outcomes Using Response- and Biology-Based Therapy for Intermediate-Risk Neuroblastoma: A Report From the Children's Oncology Group Study ANBL0531.

A. Naranjo, J. Gastier-Foster, J. Maris, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

B7-H3, a potential therapeutic target, is expressed in diffuse intrinsic pontine glioma

M. Souweidane, C. Hawkins, G. Ibrahim, 2013, Journal of Neuro-Oncology.

Pediatric pineal region masses: a single-center experience over 25 years

N. Foreman, T. Hankinson, M. Handler, 2022, Child's Nervous System.

This information is current as Tumor Types Immunophenotypes across Pediatric Brain Characterization of Distinct

V. Amani, A. Donson, N. Foreman, 2013 .

Patterns of Care for Craniopharyngioma: Survey of Members of the American Association of Neurological Surgeons

N. Foreman, Arthur K Liu, M. Torok, 2014, Pediatric Neurosurgery.

Clinical recurrence and re-resection rates after extensive vs. segmental colectomy in Crohn’s colitis: a retrospective cohort study

I. Dotan, H. Tulchinsky, J. Klausner, 2016, Techniques in Coloproctology.

Pediatric low-grade ganglioglioma: epidemiology, treatments, and outcome analysis on 348 children from the surveillance, epidemiology, and end results database.

R. Dudley, L. Hoffman, Arthur K Liu, 2015, Neurosurgery.

International survey on the management of lumbosacral cutaneous stigmata in infants with suspected occult spinal dysraphism.

K. Svokos, B. O’neill, M. Handler, 2021, Journal of neurosurgery. Pediatrics.

Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma

T. MacDonald, M. Prados, D. Neuberg, 2018, Neuro-oncology.

Hypofractionated Radiotherapy for Children With Diffuse Intrinsic Pontine Gliomas

N. Foreman, Arthur K Liu, T. Hankinson, 2016, Pediatric blood & cancer.

Chordoma Occurs in Young Children With Tuberous Sclerosis.

B. Kleinschmidt-DeMasters, Jean M. Mulcahy Levy, M. Handler, 2017, Journal of neuropathology and experimental neurology.

Headache and Chiari I Malformation in the Pediatric Population

J. Wisoff, J. Weinberg, F. Epstein, 1998, Pediatric Neurosurgery.

IMP3 Protein Expression is an Independent Prognostic Factor in Pediatric Pilocytic and Pilomyxoid Astrocytoma

A. Donson, N. Foreman, M. Handler, 2015 .

Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.

B. Kleinschmidt-DeMasters, A. Donson, N. Foreman, 2013, Journal of neuropathology and experimental neurology.

Minimally invasive technique for insertion of ventriculopleural shunt catheters.

M. Richardson, M. Handler, 2013, Journal of neurosurgery. Pediatrics.

Experience With Electrolyte Levels After Craniotomy for Pediatric Brain Tumors

J. Madden, N. Foreman, M. Handler, 2010, Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses.

Postoperative general medical ward admission following Chiari malformation decompression.

B. O’neill, T. Hankinson, M. Handler, 2022, Journal of neurosurgery. Pediatrics.

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

Michael D. Taylor, A. Dubuc, R. Vibhakar, 2012, BMC Cancer.

Vancomycin Disposition and Penetration into Ventricular Fluid of the Central Nervous System following Intravenous Therapy in Patients with Cerebrospinal Devices

K. Winston, D. Fish, P. Reiter, 2007, Pediatric Neurosurgery.

Parietal Pseudofracture and Spontaneous Intracranial Hemorrhage Suggesting Nonaccidental Trauma: Report of 2 Cases

M. Handler, L. Fenton, A. Sirotnak, 2000, Pediatric Neurosurgery.

Characterization of Distinct Immunophenotypes across Pediatric Brain Tumor Types

V. Amani, A. Donson, N. Foreman, 2013, The Journal of Immunology.

Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

T. Merchant, U. Schüller, G. Armstrong, 2021, Nature Communications.

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

A. Thorburn, K. Davies, D. Aisner, 2017, eLife.

Use of magnetic resonance imaging to detect occult spinal dysraphism in infants.

N. Stence, B. O’neill, T. Hankinson, 2017, Journal of neurosurgery. Pediatrics.

Intracranial Germ Cell Tumors: A Single Institution Experience and Review of the Literature

N. Foreman, M. Handler, A. A. Smith, 2004, Journal of Neuro-Oncology.

Increased Immune Gene Expression and Immune Cell Infiltration in High-Grade Astrocytoma Distinguish Long-Term from Short-Term Survivors

B. Kleinschmidt-DeMasters, S. Schittone, A. Donson, 2012, The Journal of Immunology.

Clinical and molecular characteristics of congenital glioblastoma.

B. Kleinschmidt-DeMasters, A. Donson, N. Foreman, 2012, Neuro-oncology.

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.

B. Kleinschmidt-DeMasters, D. Ashley, Andrea M. Muscat, 2011, Neuro-oncology.

Aurora kinase A as a rational target for therapy in glioblastoma.

Michael H Handler, Andrew M Donson, R. Vibhakar, 2010, Journal of neurosurgery. Pediatrics.

Unique Molecular Characteristics of Pediatric Myxopapillary Ependymoma

B. Kleinschmidt-DeMasters, A. Donson, N. Foreman, 2009, Brain pathology.

Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma

V. Amani, R. Vibhakar, A. Donson, 2015, Cancer Immunology Research.

Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine

A. Pierce, M. Wempe, V. Amani, 2020, Neuro-oncology advances.

Interpretation of magnetic resonance images in diffuse intrinsic pontine glioma: a survey of pediatric neurosurgeons.

N. Foreman, T. Hankinson, M. Handler, 2011, Journal of neurosurgery. Pediatrics.

Identification of FDA-Approved Oncology Drugs with Selective Potency in High-Risk Childhood Ependymoma

Elliot A. Warner, V. Amani, R. Vibhakar, 2018, Molecular Cancer Therapeutics.

Intramedullary spinal cord astrocytomas in children

N. Foreman, J. Fleitz, M. Handler, 2004, Pediatric blood & cancer.

Medulloblastoma Phenotype-associated Genes in Suppressor by Targeting Multiple Cancer MicroRNA 218 Acts as a Tumor Cell

Michael D. Taylor, A. Dubuc, R. Vibhakar, 2013 .

MicroRNA 218 Acts as a Tumor Suppressor by Targeting Multiple Cancer Phenotype-associated Genes in Medulloblastoma*

Michael D. Taylor, A. Dubuc, R. Vibhakar, 2012, The Journal of Biological Chemistry.

Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma.

T. Zhou, T. Merchant, D. Eisenstat, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Pediatric Brainstem Gangliogliomas Show BRAFV600E Mutation in a High Percentage of Cases

D. Aisner, B. Kleinschmidt-DeMasters, Amy A. Smith, 2014, Brain pathology.

CEREBRAL CAVERNOUS MALFORMATIONS: SOMATIC MUTATIONS IN VASCULAR ENDOTHELIAL CELLS

J. Gault, R. Shenkar, I. Awad, 2009, Neurosurgery.

Survey of MicroRNA expression in pediatric brain tumors

Michael H Handler, Andrew M Donson, R. Vibhakar, 2011, Pediatric blood & cancer.

Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

T. Merchant, U. Schüller, G. Armstrong, 2021, Nature Communications.

Comprehensive molecular characterization of pediatric treatment-induced high-grade glioma: A distinct entity despite disparate etiologies with defining molecular characteristics and potential therapeutic targets

Kenneth L. Jones, T. Merchant, U. Schüller, 2019, bioRxiv.

Successful Use of Intracavitary Bleomycin for Low-Grade Astrocytoma Tumor Cyst

J. Strain, N. Foreman, J. Fleitz, 1999, Pediatric Neurosurgery.

Comparison of outcomes following decompressive craniectomy in children with accidental and nonaccidental blunt cranial trauma.

N. Stence, M. Handler, L. Fenton, 2012, Journal of neurosurgery. Pediatrics.

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

B. Kleinschmidt-DeMasters, R. Vibhakar, A. Donson, 2013, Pediatric blood & cancer.

The Utility of MRI in Pediatric Trauma Patients Suspected of Having Cervical Spine Injuries.

N. Stence, D. Mirsky, B. O’neill, 2019, The journal of trauma and acute care surgery.

Prevalence of cervical spine injury in infants with head trauma.

J. Katz, M. Handler, C. Oluigbo, 2010, Journal of neurosurgery. Pediatrics.

A cervical spine mass caused by Onchocerca lupi

M. Dishop, D. Mirsky, R. Dudley, 2015, The Lancet.

A near-fatal complication of endoscopic third ventriculostomy: case report.

R. Abbott, M. Handler, Mark Lee, 1994, Neurosurgery.

Routine perioperative ketorolac administration is not associated with hemorrhage in pediatric neurosurgery patients.

B. O’neill, M. Torok, M. Richardson, 2016, Journal of neurosurgery. Pediatrics.

Identical twin sisters with Rubinstein–Taybi syndrome associated with Chiari malformations and syrinx

G. Bellus, A. Tsai, M. Handler, 2011, American journal of medical genetics. Part A.

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma

V. Amani, A. Donson, N. Foreman, 2014, Acta Neuropathologica.

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

Eric W Prince, M. Remke, Michael D. Taylor, 2015, Oncotarget.

ATYPICAL TERATOID RHABDOID TUMOR (ATRT)

R. Siebert, K. Ligon, C. Roberts, 2012 .

Specific expression of PD‐L1 in RELA‐fusion supratentorial ependymoma: Implications for PD‐1‐targeted therapy

Kenneth L. Jones, V. Amani, A. Donson, 2018, Pediatric blood & cancer.

Immune Gene and Cell Enrichment Is Associated with a Good Prognosis in Ependymoma1

Nicholas K. Foreman, Michael H. Handler, B. Kleinschmidt-DeMasters, 2009, The Journal of Immunology.

Magnetic resonance imaging-guided stereotactic laser ablation therapy for the treatment of pediatric epilepsy: a retrospective multiinstitutional study.

D. Couture, S. Huckins, G. Barnett, 2023, Journal of neurosurgery. Pediatrics.

Atypical pediatric ganglioglioma is common and associated with a less favorable clinical course.

N. Stence, Arthur K Liu, M. Torok, 2016, Journal of neurosurgery. Pediatrics.

Vascular abnormalities in pediatric craniopharyngioma patients treated with radiation therapy

L. Gaspar, N. Foreman, Arthur K Liu, 2009, Pediatric blood & cancer.

Monostotic fibrous dysplasia of the thoracic spine.

M. Handler, C. Overby, B. Rosenblum, 1987, Spine.

Predicting which children are at risk for ependymoma relapse

A. Donson, N. Foreman, M. Handler, 2006, Journal of Neuro-Oncology.

Maximally safe resection followed by hypofractionated re‐irradiation for locally recurrent ependymoma in children

L. Gaspar, N. Foreman, Arthur K Liu, 2009, Pediatric blood & cancer.

Pediatric choroid plexus tumors: epidemiology, treatments, and outcome analysis on 202 children from the SEER database

R. Dudley, Arthur K Liu, M. Torok, 2014, Journal of Neuro-Oncology.

Outcome of hospital discharge on postoperative Day 1 following uncomplicated tethered spinal cord release.

B. O’neill, T. Hankinson, M. Handler, 2016, Journal of neurosurgery. Pediatrics.

Laparoscopic placement of distal ventriculoperitoneal shunt catheters.

M. Handler, B. Callahan, 2008, Journal of neurosurgery. Pediatrics.

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

J. Johnston, Karun K. Rao, V. Amani, 2015, Acta Neuropathologica Communications.

Short-term mortality following surgical procedures for the diagnosis of pediatric brain tumors: outcome analysis in 5533 children from SEER, 2004-2011.

R. Dudley, Arthur K Liu, M. Torok, 2016, Journal of neurosurgery. Pediatrics.

Response to Journal Club: Pediatric Low-Grade Ganglioglioma: Epidemiology, Treatments, and Outcome Analysis of 348 Children From the Surveillance, Epidemiology, and End Results Database.

R. Dudley, L. Hoffman, Arthur K Liu, 2016, Neurosurgery.

Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma

M. Souweidane, J. Johnston, T. Jacques, 2017, Journal of neuropathology and experimental neurology.

Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images

Gerald Grant, Elizabeth Tyler-Kabara, George Jallo, 2020, Scientific Reports.

An 18-year-old man with fenestrated vertebral arteries, recurrent stroke and successful angiographic coiling

B. Tseng, C. Filley, B. Mull, 2007, Journal of the Neurological Sciences.

Separation of conjoined pygopagus twins.

A. Lowenstein, M. Handler, B. Morton, 2003, Plastic and reconstructive surgery.

Diagnostic accuracy of neuroimaging in pediatric optic chiasm/sellar/suprasellar tumors

Kathleen Dorris, Nicholas Stence, Todd C Hankinson, 2019, Pediatric blood & cancer.

Claudin 6 Is a Positive Marker for Atypical Teratoid/Rhabdoid Tumors

B. Kleinschmidt-DeMasters, A. Donson, N. Foreman, 2010, Brain pathology.

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

Eric W Prince, V. Amani, R. Vibhakar, 2016, BMC Cancer.

Astrocytic Inclusions in Epilepsy: Expanding the Spectrum of Filaminopathies

L. Hazrati, H. Otsubo, J. Rutka, 2008, Journal of neuropathology and experimental neurology.

Significance of FDG-PET Hypermetabolism in Children with Intractable Focal Epilepsy

N. Stence, Andrew White, D. Mirsky, 2018, Pediatric Neurosurgery.

MOMS Plus: Single-Institution Review of Outcomes for Extended BMI Criteria for Open Fetal Repair of Myelomeningocele

H. Galan, K. Liechty, M. Handler, 2019, Fetal Diagnosis and Therapy.

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma

J. Johnston, Karun K. Rao, B. Kleinschmidt-DeMasters, 2015, Acta neuropathologica communications.

Modified Hysterotomy Closure Technique for Open Fetal Surgery

T. Crombleholme, H. Galan, K. Liechty, 2017, Fetal Diagnosis and Therapy.

Rasmussen encephalitis tissue transfer program

P. Lockhart, M. Smyth, C. Cepeda, 2016, Epilepsia.

Nonoperative Management of Childhood Calvarial Langerhans-Cell Histiocytosis.

D. Limbrick, J. Ragheb, T. Niazi, 2022, The New England journal of medicine.

174 Epilepsy Surgery in Infants Under 1 Year of Age

K. Knupp, K. Chapman, M. Handler, 2014 .

Long-term survival after intralesional resection and multi-modal therapy of thoracic spine osteosarcoma.

D. Schreiber, B. Greffe, M. Handler, 2003, Medical and pediatric oncology.

Pediatric pineal region masses: a single-center experience over 25 years

N. Foreman, T. Hankinson, M. Handler, 2022, Child's Nervous System.

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo.

M. Nugent, R. Iozzo, M. Handler, 1998, The Journal of clinical investigation.

DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Noah E. Berlow, Elaine C. Huang, T. Lagerweij, 2012 .

Technical evolution of pediatric neurosurgery: the evolution of intraoperative imaging.

M. Alshareef, M. Handler, Shadi Bsat, 2023, Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery.

Single-Cell RNAseq of Childhood Ependymoma Reveals Distinct Neoplastic Cell Subpopulations that Impact Etiology, Molecular Classification and Outcome

Eric W Prince, Kenneth L. Jones, J. Hesselberth, 2020, Social Science Research Network.

A complication in removing a retained ventricular catheter using electrocautery.

M. Handler, 1996, Pediatric Neurosurgery.

Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood

Eric W Prince, V. Amani, R. Vibhakar, 2017, Journal of neuropathology and experimental neurology.