S. Pin

发表

Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping.

P. Carroll, W. Isaacs, J. Epstein, 1996, Cancer research.

Application of High-Throughput Automated Patch-Clamp Electrophysiology to Study Voltage-Gated Ion Channel Function in Primary Cortical Cultures

C. B. Puryear, T. Strassmaier, S. Pin, 2020, SLAS discovery : advancing life sciences R & D.

Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer

J. Herman, S. Baylin, W. Isaacs, 1997, Genes, chromosomes & cancer.

In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment of Major Depressive Disorder

D. Deaver, J. Bidlack, D. Arnelle, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss.

W. Isaacs, J. Barrett, J. Schalken, 1996, Cancer research.

Involves Gene Mutation or Allelic Loss during the Progression of Human Prostatic Cancer Infrequently Down-Regulation of the KAI1 Metastasis Suppressor Gene

Jin-Tang Dong, Hiroyoshi Suzuki, S. Pin, 2013 .

The design and implementation of a generic lipopeptide scanning platform to enable the identification of 'locally acting' agonists for the apelin receptor.

F. Zécri, E. Fortier, S. Pin, 2014, Bioorganic & medicinal chemistry letters.

Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery.

J. Macor, R. Schartman, G. Thalody, 2013, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent antagonists containing rigid spirocyclic privileged structures for the CGRP receptor.

J. Macor, G. Dubowchik, S. Pin, 2012, Bioorganic & medicinal chemistry letters.

Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists.

B. Bahr, S. Pin, Sokhom S. Pin, 2008, European journal of pharmacology.

Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R).

K. Browman, J. Macor, G. Dubowchik, 2010, Bioorganic & medicinal chemistry letters.

Discovery of 6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethylamines, a novel class of corticotropin-releasing factor receptor type 1 (CRF1R) antagonists.

J. Macor, D. Zuev, G. Dubowchik, 2010, Bioorganic & medicinal chemistry letters.

An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes.

K. Browman, J. Knipe, G. Dubowchik, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists.

Stella Huang, G. Dubowchik, S. Pin, 2005, Bioorganic & medicinal chemistry letters.

Calcitonin gene-related peptide (CGRP) receptor antagonists: pyridine as a replacement for a core amide group.

J. Macor, G. Dubowchik, Cen Xu, 2012, Bioorganic & medicinal chemistry letters.

Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and effici

Kimberly A. Widmann, J. Macor, R. Schartman, 2008, Journal of medicinal chemistry.

Calcitonin gene-related peptide (CGRP) receptor antagonists: novel aspartates and succinates.

J. Macor, G. Dubowchik, Cen Xu, 2012, Bioorganic & medicinal chemistry letters.

CG island methylation changes near the GSTP1 gene in prostatic intraepithelial neoplasia.

J. Brooks, W. Isaacs, J. Epstein, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer.

W. Isaacs, G. Bova, R. Bookstein, 1996, Genomics.

Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.

K. Browman, G. Dubowchik, S. Pin, 2005, Bioorganic & medicinal chemistry letters.

2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy.

K. Browman, D. Zuev, P. Scola, 2003, Bioorganic & medicinal chemistry letters.

Preparation of imidazoles as potent calcitonin gene-related peptide (CGRP) antagonists.

Kimberly A. Widmann, J. Macor, R. Schartman, 2013, Bioorganic & medicinal chemistry letters.

Azepino-indazoles as calcitonin gene-related peptide (CGRP) receptor antagonists.

Kimberly A. Widmann, Ping Chen, J. Macor, 2020, Bioorganic & medicinal chemistry letters.

Parkinson disease among patients treated for benign prostatic hyperplasia with α1 adrenergic receptor antagonists.

D. Stone, J. Renger, S. Duvvuri, 2021, The Journal of clinical investigation.