S. Lepetre-Mouelhi

发表

Translation of nanomedicines from lab to industrial scale synthesis: The case of squalene-adenosine nanoparticles.

P. Couvreur, F. Testard, D. Desmaële, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Interaction of self-assembled squalenoyl gemcitabine nanoparticles with phospholipid-cholesterol monolayers mimicking a biomembrane.

P. Couvreur, B. Stella, V. Rosilio, 2011, Langmuir : the ACS journal of surfaces and colloids.

Synthesis and physicochemical characterization of new squalenoyl amphiphilic gadolinium complexes as nanoparticle contrast agents.

P. Couvreur, S. Laurent, L. Vander Elst, 2011, Organic & biomolecular chemistry.

Novel PEGylated Nanoassemblies Made of Self‐Assembled Squalenoyl Nucleoside Analogues

P. Couvreur, H. Hillaireau, J. Nicolas, 2008 .

Squalenoyl nanomedicines as potential therapeutics.

P. Couvreur, L. Cattel, B. Stella, 2006, Nano letters.

Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery

P. Couvreur, A. Klymchenko, S. Yesylevskyy, 2017, Nature Communications.

Squalenoyl Gemcitabine Monophosphate: Synthesis, Characterisation of Nanoassemblies and Biological Evaluation

P. Couvreur, S. Wack, E. Lepeltier, 2011 .

Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: an original drug delivery pathway.

P. Couvreur, V. Nicolas, C. Dubernet, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Micro- and Nanocarriers for pain alleviation.

P. Couvreur, S. Lepetre-Mouelhi, Alexandre da Silva, 2022, Advanced drug delivery reviews.

Transport Mechanisms of Squalenoyl-Adenosine Nanoparticles Across the Blood–Brain Barrier

P. Couvreur, K. Braeckmans, V. Nicolas, 2015 .

Extracellular-protein-enhanced cellular uptake of squalenoyl gemcitabine from nanoassemblies

P. Couvreur, C. Dubernet, D. Desmaële, 2010 .

Squalenoyl nucleoside monophosphate nanoassemblies: new prodrug strategy for the delivery of nucleotide analogues.

P. Couvreur, S. Wack, D. Desmaële, 2010, Bioorganic & medicinal chemistry letters.

Interaction of a new anticancer prodrug, gemcitabine-squalene, with a model membrane: coupled DSC and XRD study.

P. Couvreur, H. Amenitsch, M. Ollivon, 2010, Biochimica et Biophysica Acta.

Freeze-drying of squalenoylated nucleoside analogue nanoparticles.

P. Couvreur, H. Hillaireau, C. Dubernet, 2009, International journal of pharmaceutics.

Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug?

A. IJzerman, P. Couvreur, J. Mougin, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Interaction of an amphiphilic squalenoyl prodrug of gemcitabine with cellular membranes.

P. Couvreur, F. Meneau, S. Wack, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Squalenoylation Favorably Modifies the in Vivo Pharmacokinetics and Biodistribution of Gemcitabine in Mice

A. Paci, G. Vassal, P. Couvreur, 2008, Drug Metabolism and Disposition.

Adenosine and lipids: A forced marriage or a love match?

P. Couvreur, M. Rouquette, S. Lepetre-Mouelhi, 2019, Advanced drug delivery reviews.

Towards a clinical application of freeze-dried squalene-based nanomedicines

F. Testard, J. Michel, M. Rouquette, 2019, Journal of drug targeting.

Liposomal squalenoyl-gemcitabine: formulation, characterization and anticancer activity evaluation.

P. Couvreur, D. Desmaële, L. H. Reddy, 2010, Nanoscale.

Influence of the nanoprecipitation conditions on the supramolecular structure of squalenoyled nanoparticles.

P. Couvreur, H. Amenitsch, V. Rosilio, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Discovery of new hexagonal supramolecular nanostructures formed by squalenoylation of an anticancer nucleoside analogue.

Patrick Couvreur, P. Couvreur, J. Poupaert, 2008, Small.

Squalenoyl Adenosine Nanoparticles provide Neuroprotection after Stroke and Spinal Cord Injury

P. Couvreur, V. Nicolas, N. Hildebrandt, 2014, Nature nanotechnology.

A new painkiller nanomedicine to bypass the blood-brain barrier and the use of morphine

M. Hamon, P. Couvreur, S. Mura, 2019, Science Advances.

Anticancer efficacy of squalenoyl gemcitabine nanomedicine on 60 human tumor cell panel and on experimental tumor.

P. Couvreur, J. Renoir, D. Desmaële, 2009, Molecular pharmaceutics.

Pharmacokinetics, biodistribution and metabolism of squalenoyl adenosine nanoparticles in mice using dual radio-labeling and radio-HPLC analysis

P. Couvreur, A. Gaudin, J. Mougin, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Albumin-driven disassembly of lipidic nanoparticles: the specific case of the squalene-adenosine nanodrug.

P. Couvreur, I. Grillo, F. Wien, 2020, Nanoscale.

Self-assembly of squalene-based nucleolipids: relating the chemical structure of the bioconjugates to the architecture of the nanoparticles.

P. Couvreur, J. Poupaert, F. Meneau, 2013, Langmuir : the ACS journal of surfaces and colloids.

Assessment of Squalene-Adenosine Nanoparticles in Two Rodent Models of Cardiac Ischemia-Reperfusion

P. Couvreur, V. Nicolas, C. Cailleau, 2023, Pharmaceutics.

Self-assembled lipid–prodrug nanoparticles

P. Couvreur, E. Garbayo, M. Blanco-Prieto, 2023, Nature Reviews Bioengineering.

New Enkephalin Nanomedicines for Pain Alleviation, Overcoming the Side Effects of Morphine

P. Couvreur, Jiao Feng, S. Lepetre-Mouelhi, 2021 .

NANO-OBJECTS IN BIOLOGICAL FLUIDS: FROM DETECTION OF ENDOGENOUS VESICLES TO NANOTOXICITY OF EXOGENOUS NANOPARTICLES

P. Couvreur, I. Grillo, F. Wien, 2019 .

A nanomedicine approach for the treatment of long-lasting pain.

C. Cailleau, S. Lepetre-Mouelhi, Julie Mougin, 2024, Journal of controlled release : official journal of the Controlled Release Society.

Nanomedicine and voltage-gated sodium channel blockers in pain management: a game changer or a lost cause?

S. Lepetre-Mouelhi, Adélaïde Le Franc, Alexandre Da Silva, 2024, Drug delivery and translational research.