V. Taylor

发表

Novel Immunosuppression: R348, a JAK3- and Syk-Inhibitor Attenuates Acute Cardiac Allograft Rejection

E. Masuda, R. Robbins, J. Velotta, 2008, Transplantation.

Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen

V. Markovtsov, C. Low, Y. Hitoshi, 2009, Journal of Cancer Research and Clinical Oncology.

diaphragmced protease activation in the Oxidative stress is required for mechanical

S. Powers, L. Koch, S. Britton, 2015 .

Developmental toxicity associated with receptor tyrosine kinase Ret inhibition in reproductive toxicity testing.

E. Masuda, V. Taylor, E. Grossbard, 2009, Birth defects research. Part A, Clinical and molecular teratology.

Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction

S. Powers, Ira J. Smith, D. Payan, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A Novel Role for p21-Activated Protein

D. Payan, P. Chu, Jorge Pardo, 2004 .

Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma

L. Rönnblom, A. Laurence, D. Zervas, 2022, Drug design, development and therapy.

Identification of the Syk kinase inhibitor R112 by a human mast cell screen.

D. Payan, E. Masuda, Rajinder Singh, 2006, The Journal of allergy and clinical immunology.

JAK1/3 signaling pathways are key initiators of T H 2 differentiation and lung allergic responses

E. Gelfand, A. Joetham, K. Takeda, 2014 .

A Novel JAK3 Inhibitor, R348, Attenuates Chronic Airway Allograft Rejection

E. Masuda, R. Robbins, J. Velotta, 2009, Transplantation.

The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation

T. Renné, M. Kiefmann, H. Reichenspurner, 2016, Transplantation.

R406, an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation

D. Payan, Haoran Zhao, K. Qu, 2006, Journal of Pharmacology and Experimental Therapeutics.

A Novel Role for p21-Activated Protein Kinase 2 in T Cell Activation

Jun Wu, D. Payan, P. Chu, 2004, The Journal of Immunology.

A Novel Role for p 21-Activated Protein Kinase 2 in T Cell Activation

Jun Wu, D. Payan, P. Chu, 2004 .

Design, synthesis of diaminopyrimidine inhibitors targeting IgE- and IgG-mediated activation of Fc receptor signaling.

D. Payan, Haoran Zhao, E. Masuda, 2015, Bioorganic & medicinal chemistry letters.

Significant Reduction of Acute Cardiac Allograft Rejection by Selective Janus Kinase-1/3 Inhibition Using R507 and R545

R. Robbins, T. Streichert, T. Deuse, 2012, Transplantation.

JAK3 Inhibition Significantly Attenuates Psoriasiform Skin Inflammation in CD18 Mutant PL/J Mice

D. Bullard, D. Payan, J. Wicks, 2009, The Journal of Immunology.

Mutant PL / J Mice Psoriasiform Skin Inflammation in CD 18 JAK 3 Inhibition Significantly Attenuates

D. Bullard, D. Payan, J. Wicks, 2009 .

Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate.

D. Payan, E. Masuda, Hui Li, 2022, ACS Medicinal Chemistry Letters.

DDDT_A_354291 2901..2917

L. Rönnblom, A. Laurence, D. Zervas, 2022 .

Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension

M. Kappus, V. Taylor, A. Barbas, 2018, Transplant Infectious Disease.

Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses.

E. Gelfand, A. Joetham, Hui Li, 2014, The Journal of allergy and clinical immunology.

Bicyclic pyrimidine compounds as potent IRAK4 inhibitors.

D. Payan, E. Masuda, Hui Li, 2022, Bioorganic & medicinal chemistry letters.

Discovery of 5-Aryl-2,4-diaminopyrimidine Compounds as Potent and Selective IRAK4 Inhibitors.

D. Payan, E. Masuda, V. Taylor, 2022, ACS medicinal chemistry letters.

OP0133 PRECLINICAL EFFICACY OF R835, A NOVEL IRAK1/4 DUAL INHIBITOR, IN RODENT MODELS OF JOINT INFLAMMATION

V. Markovtsov, E. Masuda, S. Yi, 2020 .

An Orally Bioavailable Inhibitor of FLT3 and Syk Kinases Prevents Tumor Growth in Subcutaneously Implanted Human Tumor Xenografts and Promotes Cell Death of FLT3 Mutant AML Cells.

Y. Hitoshi, V. Taylor, E. Grossbard, 2005 .

JAK3 Inhibition Significantly Attenuates Psoriasiform Skin Inflammation in CD18 Mutant PL/J Mice

D. Bullard, D. Payan, J. Wicks, 2009, Journal of Immunology.

In Vitro and in Vivo Inhibition of JAK2 Signaling by Potent and Selective JAK2 Inhibitor

V. Markovtsov, C. Low, Y. Hitoshi, 2008 .