V. Harmat

发表

The Structure of the Complex of Calmodulin with KAR-2

Judit Ovádi, Gábor Náray-Szabó, András Perczel, 2005, Journal of Biological Chemistry.

Achieving Functionality Through Modular Build-Up: Structure and Size Selection of Serine Oligopeptidases.

D. Menyhárd, V. Harmat, A. Kiss-Szemán, 2019, Current protein & peptide science.

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins

Helena Zábranská, I. Pichová, I. Simon, 2006, Nucleic acids research.

Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects

L. Kőhidai, Z. Szász, Tamás Jernei, 2020, Molecules.

Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad

I. Jákli, A. Perczel, N. Hosogi, 2022, Chemical science.

Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation

M. Wilmanns, P. Gál, Z. Nagy, 2022, The Journal of biological chemistry.

Crystal and solution structures of calcium complexes relevant to problematic waste disposal: calcium gluconate and calcium isosaccharinate

S. Brockhauser, I. Pálinkó, V. Bugris, 2018, Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials.

Synthesis and fragmentation of new 2-phosphabicyclo[2.2.2]octene 2-oxides

G. Keglevich, K. Ludányi, V. Harmat, 2002 .

Synthesis, spectral- and theoretical study, x-ray analysis, and antiproliferative activity of 4,5-dihydrobenzoferroceno[1,2-d][1,2,3]selenadiazole and its benzo-fused analogue

A. Csámpai, Tibor Pasinszki, I. Zupkó, 2018 .

Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone.

G. Gógl, V. Harmat, L. Nyitray, 2020, Structure.

Lipophilicity of aminopyridazinone regioisomers.

P. Mátyus, B. Balogh, D. Szabó, 2003, Journal of agricultural and food chemistry.

Thermally Induced Solid-Phase Quasi-Intramolecular Redox Reactions of [Hexakis(urea-O)iron(III)] Permanganate: An Easy Reaction Route to Prepare Potential (Fe,Mn)Ox Catalysts for CO2 Hydrogenation

A. Farkas, Z. Czégény, L. Kótai, 2022, Inorganic chemistry.

Theoretical Aspects of Molecular Recognition

V. Harmat, G. Náray‐Szabó, 2009 .

Comparison of ligand binding and conformational stability of human calmodulin with its homolog from the malaria parasite Plasmodium falciparum

K. Liliom, J. Kardos, T. Juhász, 2020, FASEB bioAdvances.

A True Autoactivating Enzyme

G. Ambrus, P. Gál, Robert B Sim, 2005, Journal of Biological Chemistry.

Crystallization and preliminary crystallographic analysis of dUTPase from the φ11 helper phage of Staphylococcus aureus.

B. Vértessy, G. Róna, I. Zagyva, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Probing calmodulin - peptide interactions of different species with the same target peptide

K. Liliom, T. Juhász, V. Harmat, 2016 .

Simultaneous binding of drugs with different chemical structures to Ca2+-calmodulin: crystallographic and spectroscopic studies.

J. Ovádi, F. Orosz, B. Vértessy, 1998, Biochemistry.

Origin of problems related to Staudinger reduction in carbopeptoid syntheses

A. Perczel, A. Nagy, V. Harmat, 2016, Amino Acids.

1,3-Dipolar Cycloaddition of Isatin-Derived Azomethine Ylides with 2 H-Azirines: Stereoselective Synthesis of 1,3-Diazaspiro[bicyclo[3.1.0]hexane]oxindoles.

L. Puskás, J. Wölfling, V. Harmat, 2019, The Journal of organic chemistry.

Strong influence of intramolecular Si...O proximity on reactivity: Systematic molecular structure, solvolysis, and mechanistic study of cyclic N-trimethylsilyl carboxamide derivatives

G. Pongor, János Eőri, V. Harmat, 2017 .

Novel ring transformations of condensed [1,2,4]triazolo[4,3-b]pyridazine-6(5H)-one-3(2H)-thiones effected by dialkyl-acetylenedicarboxylates

A. Csámpai, O. Barabas, V. Harmat, 2001 .

One-pot transformation of cyclic phosphine oxides to phosphine–boranes by dimethyl sulfide–borane

A. Dobó, G. Keglevich, M. Fekete, 2000 .

Steric hindrance in the synthesis and properties of the dimer of 1‐(2,4,6‐Tri‐tert‐butylphenyl)phosphole 1‐oxide

G. Keglevich, Z. Böcskei, V. Harmat, 1997 .

Structure and mechanism of hydrolysis of diaryl(acylamino)(chloro)-λ4-sulfanes and diaryl(acylamino)sulfonium salts

A. Csámpai, V. Harmat, D. Szabó, 2001 .

Approaches to Pyranuronic β‐Sugar Amino Acid Building Blocks of Peptidosaccharide Foldamers

A. Perczel, V. Harmat, I. Pintér, 2018 .

Structure determination and molecular modelling of an unexpected side product of a cyclopropane lactone formation process

Z. Finta, I. Kövesdi, V. Harmat, 2004 .

Efficient synthesis and resolution of (±)-1-[2-carboxy-6-(trifluoromethyl)phenyl]pyrrole-2-carboxylic acid

Z. Böcskei, G. Tárkányi, V. Harmat, 2000 .

Surprisingly great difference in reactivity depending upon the ring size: Solvolysis and molecular structure study of some N-trimethylsilylated cyclic ureas

G. Pongor, Z. Böcskei, V. Harmat, 2005 .

Configuration controlled crystal and/or gel formation of protected D-Glucosamines supported by promiscuous interaction surfaces and a conformationally heterogeneous solution state.

A. Perczel, D. Menyhárd, V. Harmat, 2020, Chemistry.

Reaction of cyclopropane carboxylic acid derivatives with sulphur tetrafluoride — an example of a diastereoselective ring opening

Z. Finta, V. Harmat, F. Faigl, 2000 .

Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition.

G. Katona, L. Gráf, A. Perczel, 2005, Journal of molecular biology.

Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway*

P. Gál, P. Závodszky, K. Szilágyi, 2013, The Journal of Biological Chemistry.

A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii

L. Polgár, D. Menyhárd, V. Harmat, 2013, The Journal of Biological Chemistry.

Structure and Catalysis of Acylaminoacyl Peptidase

L. Polgár, T. Beke-Somfai, D. Menyhárd, 2010, The Journal of Biological Chemistry.

Characterization of a novel acylaminoacyl peptidase with hexameric structure and endopeptidase activity.

L. Polgár, A. Kiss, V. Harmat, 2009, Biochimica et biophysica acta.

Structure and enzymatic mechanism of a moonlighting dUTPase.

J. Szabó, B. Vértessy, J. Tóth, 2013, Acta crystallographica. Section D, Biological crystallography.

Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase.

L. Polgár, A. Kiss, V. Harmat, 2008, Journal of structural biology.

The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity.

L. Polgár, T. Juhász, B. Sztáray, 2007, Journal of molecular biology.

Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality.

Z. Orgován, D. Menyhárd, V. Harmat, 2015, Acta crystallographica. Section D, Biological crystallography.

Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis.

R. Neutze, G. Katona, L. Gráf, 2006, Biochemistry.

A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies.

Andrea Sántáné Csutor, J. Ovádi, B. Vértessy, 2000, Journal of molecular biology.

C1 Inhibitor Serpin Domain Structure Reveals the Likely Mechanism of Heparin Potentiation and Conformational Disease*

P. Gál, P. Závodszky, J. Dobó, 2007, Journal of Biological Chemistry.

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2*

M. Wilmanns, P. Gál, P. Závodszky, 2012, The Journal of Biological Chemistry.

The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions.

G. Ambrus, P. Gál, P. Závodszky, 2004, Journal of molecular biology.

Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides

Annamária F. Ángyán, Z. Gáspári, P. Gál, 2022, ACS chemical biology.

Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome

Gergely Katona, László Nyitray, W. Y. Wahlgren, 2011, PloS one.

Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules.

K. Kánai, G. Ferenczy, Z. Böcskei, 2008, Journal of medicinal chemistry.

Novel ortho- and peri-fused pyridazine ring systems

P. Mátyus, G. Horváth, V. Harmat, 2003 .

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity1

P. Gál, P. Závodszky, J. Dobó, 2009, The Journal of Immunology.

Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase

B. Vértessy, J. Tóth, V. Harmat, 2010, Nucleic acids research.

Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases

E. Takács, B. Vértessy, J. Tóth, 2010, FEBS letters.

Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid‐protein interactions

B. Vértessy, J. Tóth, E. Kovács, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural Evidence for Non-canonical Binding of Ca2+ to a Canonical EF-hand of a Conventional Myosin*

K. Kohama, J. Debreczeni, L. Farkas, 2005, Journal of Biological Chemistry.

Radiation-damage investigation of a DNA 16-mer.

E. Garman, S. Brockhauser, V. Bugris, 2019, Journal of synchrotron radiation.

Dynamic disorder in the high-temperature polymorph of bis[diamminesilver(I)] sulfate—reasons and consequences of simultaneous ammonia release from two different polymorphs

A. Farkas, L. Kótai, V. Petruševski, 2021, Journal of Coordination Chemistry.

Fragmentation‐related phosphinylations using 2‐aryl‐2‐phosphabicyclo[2.2.2]oct‐ 5‐ene‐ and ‐octa‐5,7‐diene 2‐oxides

Kálmán Simon, György Keglevich, Tímea Imre, 2003 .

Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.

L. Gráf, P. Gál, P. Závodszky, 2008, Molecular immunology.

Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region.

P. Gál, P. Závodszky, J. Dobó, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Effect of a trifluoromethyl group on molecular structure: Competitive mono- and dilithiation of 1-[(trifluoromethyl)phenyl]pyrroles

G. Keserű, Z. Böcskei, V. Harmat, 1999 .

Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions

K. Liliom, T. Juhász, V. Harmat, 2023, The Journal of biological chemistry.

Reveals the Basis of Its Broad Specificity Protease: Structure of Its Catalytic Region MASP-1, a Promiscuous Complement

P. Závodszky, J. Dobó, V. Harmat, 2009 .

Synthesis and Fragmentation of New 2-Phosphabicyclo[2.2.2]octene 2-Oxides.

K. Ludányi, V. Harmat, G. Keglevich, 2003 .

Structural Diversity in Calmodulin - Peptide Interactions.

V. Harmat, Z. Dürvanger, 2019, Current protein & peptide science.