Xiner Huang

发表

SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19

K. To, Jian-Piao Cai, J. Chan, 2020, Cellular and Molecular Gastroenterology and Hepatology.

Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity

Jian-Piao Cai, J. Chan, K. Yuen, 2021, Science Advances.

Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation

Jian-Piao Cai, J. Chan, K. Yuen, 2020, The Journal of infectious diseases.

Emerging SARS-CoV-2 variants expand species tropism to rodents

K. To, Jian-Piao Cai, W. Chan, 2021 .

STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells

J. Chan, Jie Zhou, H. Chu, 2021, Emerging microbes & infections.

Targeting ACLY efficiently inhibits SARS-CoV-2 replication

Jian-Piao Cai, J. Chan, H. Chu, 2022, International journal of biological sciences.

Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron

K. To, Jian-Piao Cai, J. Chan, 2021, Nature.

Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters.

Jian-Piao Cai, Kwok-Hung Chan, Cuiting Luo, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2

Jian-Piao Cai, Cuiting Luo, K. Yuen, 2022, Cell Reports Medicine.

Bacillus Calmette-Guérin–induced trained immunity protects against SARS-CoV-2 challenge in K18-hACE2 mice

Jian-Piao Cai, J. Chan, I. Hung, 2022, JCI insight.

Coronaviruses exploit a host cysteine-aspartic protease for replication

Jian-Piao Cai, Cuiting Luo, J. Chan, 2022, Nature.

Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2

J. Chan, K. Yuen, H. Chu, 2022, Emerging microbes & infections.

Novel coronavirus mutations: Vaccine development and challenges

W. Wang, Xiner Huang, Qingqing Chen, 2022, Microbial Pathogenesis.

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

Dong Yang, K. To, Jian-Piao Cai, 2020, Nature Communications.

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study

O. Tsang, K. To, D. Lung, 2020, The Lancet Microbe.

Conditional gene inactivation by combining tetracycline-mediated transcriptional repression and auxin-inducible degron-mediated degradation

R. Poon, Xiner Huang, Nelson Lee, 2019, Cell cycle.

Emerging SARS-CoV-2 variants expand species tropism to murines

K. To, Jian-Piao Cai, W. Chan, 2021, EBioMedicine.

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

Dong Yang, Yuxin Hou, Yue Chai, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-β and IFN inducer

Jian-Piao Cai, J. Chan, K. Yuen, 2020, Journal of Infection.

The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA.1, BA.2, and BA.5

K. To, Jian-Piao Cai, Lin-Lei Chen, 2023, EBioMedicine.

Altered host protease determinants for SARS-CoV-2 Omicron

Jian-Piao Cai, J. Chan, K. Yuen, 2023, Science advances.

Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination

Cuiting Luo, Rui Qiao, H. Chu, 2023, bioRxiv.

Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron

K. To, Jian-Piao Cai, J. Chan, 2022, Nature.

Divergent trajectory of replication and intrinsic pathogenicity of SARS-CoV-2 Omicron post-BA.2/5 subvariants in the upper and lower respiratory tract

K. To, Jian-Piao Cai, Shuofeng Yuan, 2023, EBioMedicine.

Type‐II IFN inhibits SARS‐CoV‐2 replication in human lung epithelial cells and ex vivo human lung tissues through indoleamine 2,3‐dioxygenase‐mediated pathways

Shuofeng Yuan, A. J. Zhang, Yuanchen Liu, 2024, Journal of Medical Virology.