B. Becknell

发表

The diagnosis, evaluation and treatment of acute and recurrent pediatric urinary tract infections

B. Becknell, Megan S Schober, Lindsey Korbel, 2015, Expert review of anti-infective therapy.

Expression and Antimicrobial Function of Beta-Defensin 1 in the Lower Urinary Tract

X. Chen, K. McHugh, S. Justice, 2013, PloS one.

New directions in natural killer cell-based immunotherapy of human cancer

M. Caligiuri, B. Blaser, S. Farag, 2003, Expert opinion on biological therapy.

Uroepithelial thickening improves detection of vesicoureteral reflux in infants with prenatal hydronephrosis.

C. Ching, D. McLeod, B. Becknell, 2016, Journal of pediatric urology.

Uroepithelial Thickening on Sonography Improves Detection of Vesicoureteral Reflux in Children with First Febrile Urinary Tract Infection.

D. McLeod, B. Becknell, Z. Gordon, 2015, The Journal of urology.

Urothelial progenitors in development and repair

B. Becknell, C. Bates, S. Narla, 2021, Pediatric Nephrology.

Roles for urothelium in normal and aberrant urinary tract development

C. Ching, K. McHugh, B. Becknell, 2020, Nature Reviews Urology.

The uroplakin plaque promotes renal structural integrity during congenital and acquired urinary tract obstruction.

C. Ching, K. McHugh, B. Becknell, 2018, American journal of physiology. Renal physiology.

Crucial Roles of the Protein Kinases MK2 and MK3 in a Mouse Model of Glomerulonephritis

S. Agrawal, M. Gaestel, J. Kopp, 2013, PloS one.

The PP2A inhibitor SET regulates natural killer cell IFN-γ production

M. Caligiuri, A. Ferketich, B. Blaser, 2007, The Journal of experimental medicine.

Natural Killer Cells in Innate Immunity and Cancer

M. Caligiuri, B. Becknell, 2008, Journal of immunotherapy.

Hepatoblastoma and prune belly syndrome: a potential association

K. McHugh, A. Schwaderer, M. Ranalli, 2011, Pediatric Nephrology.

Cancer T cell therapy expands

M. Caligiuri, B. Becknell, 2003, Nature Medicine.

Expression and Significance of the HIP/PAP and RegIIIγ Antimicrobial Peptides during Mammalian Urinary Tract Infection

C. Ching, K. McHugh, A. Schwaderer, 2015, PloS one.

Trends in pediatric urolithiasis: patient characteristics, associated diagnoses, and financial burden

A. Schwaderer, B. Becknell, Kirsten Kusumi, 2015, Pediatric Nephrology.

Albuminuria in pediatric neurogenic bladder: Identifying an earlier marker of renal disease.

C. Ching, A. Salvator, D. McLeod, 2019, Urology.

Interplay of RUNX 1 / MTG 8 and DNA Methyltransferase 1 in Acute Myeloid Leukemia

J. Byrd, C. Plass, G. Marcucci, 2005 .

Acute Myeloid Leukemia Interplay of RUNX 1 / MTG 8 and DNA Methyltransferase 1 in Updated

J. Byrd, C. Plass, G. Marcucci, 2005 .

Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

J. Byrd, C. Plass, G. Marcucci, 2005, Cancer research.

Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells.

M. Caligiuri, D. Jarjoura, B. Blaser, 2007, Blood.

Neutrophil-Macrophage Imbalance Drives the Development of Renal Scarring during Experimental Pyelonephritis.

J. Rangel-Moreno, S. Justice, B. Becknell, 2020, Journal of the American Society of Nephrology : JASN.

Interleukin-6/Stat3 signaling has an essential role in the host antimicrobial response to urinary tract infection.

C. Ching, K. McHugh, B. Becknell, 2018, Kidney international.

Differential expression of SHIP1 in CD56bright and CD56dim NK cells provides a molecular basis for distinct functional responses to monokine costimulation.

M. Caligiuri, R. Trotta, W. Ding, 2005, Blood.

A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells.

M. Caligiuri, G. Nuovo, A. Ferketich, 2005, Immunity.

Interleukin-2, interleukin-15, and their roles in human natural killer cells.

M. Caligiuri, B. Becknell, 2005, Advances in immunology.

Insulin and the PI3K/AKT Signaling Pathway Regulate Ribonuclease 7 Expression in the Human Urinary Tract

A. Schwaderer, B. Becknell, J. Spencer, 2017 .

Insulin and the phosphatidylinositol 3-kinase signaling pathway regulate Ribonuclease 7 expression in the human urinary tract.

D. Cohen, S. Tridandapani, A. Schwaderer, 2016, Kidney international.

Urothelial progenitors in development and repair

B. Becknell, C. Bates, S. Narla, 2021, Pediatric Nephrology.

Responsiveness of Naive CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation1

M. Caligiuri, R. Harvey, B. Becknell, 2006, The Journal of Immunology.

Th1 and Th2 Cell Differentiation Polarizing Cytokine Determines the Ratio of Responsiveness of Naive CD4 T Cells to

M. Caligiuri, B. Becknell, R. Harvey, 2006 .

Cell-specific qRT-PCR of renal epithelial cells reveals a novel innate immune signature in murine collecting duct.

G. Schwartz, R. Nelson, A. Schwaderer, 2018, American journal of physiology. Renal physiology.

Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.

C. Ching, K. L. La Perle, L. Solden, 2019, Journal of the American Society of Nephrology : JASN.

Human Alpha Defensin 5 Expression in the Human Kidney and Urinary Tract

C. Bevins, A. Schwaderer, B. Becknell, 2012, PloS one.

Transcriptional control of human T‐BET expression: The role of Sp1

M. Caligiuri, D. Jarjoura, G. Marcucci, 2007, European journal of immunology.

Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity.

M. Caligiuri, D. Kusewitt, A. Ferketich, 2006, Blood.

Inflammation drives renal scarring in experimental pyelonephritis.

C. Ching, K. McHugh, B. Bolon, 2017, American journal of physiology. Renal physiology.

Innate immunity and urinary tract infection

C. Ching, B. Becknell, J. Spencer, 2019, Pediatric Nephrology.

Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.

M. Caligiuri, G. Nuovo, Lai Wei, 2010, Immunity.

Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22.

M. Caligiuri, G. Nuovo, A. Freud, 2009, Blood.

Evidence for discrete stages of human natural killer cell differentiation in vivo

M. Caligiuri, A. Ferketich, A. Freud, 2006, The Journal of experimental medicine.

PRDM1/Blimp-1 Controls Effector Cytokine Production in Human NK Cells

M. Caligiuri, Sheng Wei, K. Wright, 2010, The Journal of Immunology.

Common clinical markers predict end-stage renal disease in children with obstructive uropathy

C. Ching, S. Furth, K. McHugh, 2018, Pediatric Nephrology.

Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function

Logan A. Walker, P. White, G. Schwartz, 2019, Scientific Reports.

Carbonic anhydrase 2 deficiency leads to increased pyelonephritis susceptibility.

G. Schwartz, A. Schwaderer, B. Becknell, 2014, American journal of physiology. Renal physiology.

The PP2A inhibitor SET regulates natural killer cell IFN- (cid:4) production

M. Caligiuri, A. Ferketich, B. Blaser, 2007 .

Urinary antimicrobial peptides: Potential novel biomarkers of obstructive uropathy.

C. Ching, K. McHugh, D. DaJusta, 2018, Journal of pediatric urology.

The Interaction between Enterobacteriaceae and Calcium Oxalate Deposits

A. Wolfe, K. Thomas-White, A. Schwaderer, 2015, PloS one.

Efficient infection of human natural killer cells with an EBV/retroviral hybrid vector.

M. Caligiuri, R. Trotta, W. Ding, 2005, Journal of immunological methods.

Impact of successful pediatric ureteropelvic junction obstruction surgery on urinary HIP/PAP and BD-1 levels.

C. Ching, K. McHugh, D. DaJusta, 2020, Journal of pediatric urology.

Novel role for androgen signaling in pyelonephritis.

C. Ching, B. Becknell, 2018, Kidney international.

Longitudinal kidney injury biomarker trajectories in children with obstructive uropathy

C. Ching, S. Furth, D. McLeod, 2020, Pediatric Nephrology.

A new 'tac' for childhood nephrotic syndrome.

L. Greenbaum, B. Becknell, W. Smoyer, 2012, Kidney international.

The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse.

G. Lesinski, J. Durbin, W. Carson, 2003, The Journal of clinical investigation.

The demographics and costs of inpatient vesicoureteral reflux management in the USA

K. McHugh, B. VanderBrink, A. Schwaderer, 2011, Pediatric Nephrology.

Trans IL-6 signaling does not appear to play a role in renal scarring after urinary tract infection.

C. Ching, B. Becknell, Sudipti Gupta, 2020, Journal of pediatric urology.

Struvite urolithiasis and chronic urinary tract infection in a murine model of urinary diversion.

J. Asplin, K. McHugh, B. Bolon, 2013, Urology.

The innate immune response during urinary tract infection and pyelonephritis

A. Schwaderer, B. Becknell, J. Spencer, 2013, Pediatric Nephrology.

Urine Stasis Predisposes to Urinary Tract Infection by an Opportunistic Uropathogen in the Megabladder (Mgb) Mouse

Michael E. Wilhide, B. Becknell, Birong Li, 2015, PloS one.

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.

M. Caligiuri, Lizhao Wu, G. Leone, 2006, The Journal of clinical investigation.

The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy.

M. Caligiuri, C. Bloomfield, C. Plass, 2005, Blood.

Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.

M. Caligiuri, C. Bloomfield, R. Larson, 2001, Cancer research.

Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420.

Edward J. Lee, M. Caligiuri, C. Bloomfield, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

STAT‐1‐mediated repression of monocyte interleukin‐10 gene expression in vivo

M. Caligiuri, G. Nuovo, B. Ahmer, 2006, European journal of immunology.

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia.

M. Caligiuri, C. Bloomfield, C. Croce, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia.

V. P. Eswarakumar, J. Bertram, S. Sims-Lucas, 2009, American journal of physiology. Renal physiology.

Deletion of Frs2 (cid:1) from the ureteric epithelium causes renal hypoplasia

V. P. Eswarakumar, J. Bertram, S. Sims-Lucas, 2009 .

Leukemia-associated Rho Guanine Nucleotide Exchange Factor, a Dbl Family Protein Found Mutated in Leukemia, Causes Transformation by Activation of RhoA*

M. Caligiuri, K. Wennerberg, C. Der, 2001, The Journal of Biological Chemistry.

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A.

Susan S. Taylor, M. Mann, S. Korsmeyer, 1999, Molecular cell.

Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia

Wei Ding, Guido Marcucci, Christoph Plass, 2005, Nature Genetics.

The antitumor effects of IFNa are abrogated in a STAT 1-deficient mouse

G. Lesinski, J. Durbin, W. Carson, 2018 .

The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse

G. Lesinski, J. Durbin, W. Carson, 2003 .

Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis

N. A. Walton, M. Caligiuri, D. Felsher, 2007, Proceedings of the National Academy of Sciences.

Krt5+ Urothelial Cells are Developmental and Tissue Repair Progenitors in the Kidney.

C. Ching, K. McHugh, B. Becknell, 2019, American journal of physiology. Renal physiology.

Polymorphisms in α-Defensin-Encoding DEFA1A3 Associate with Urinary Tract Infection Risk in Children with Vesicoureteral Reflux.

J. Manak, D. Cohen, N. Shaikh, 2016, Journal of the American Society of Nephrology : JASN.

Differentiating Asymptomatic Bacteriuria From Urinary Tract Infection in the Pediatric Neurogenic Bladder Population: NGAL As a Promising Biomarker.

C. Ching, B. Becknell, J. Preece, 2019, Topics in spinal cord injury rehabilitation.

Urinary Tract Infections.

B. Becknell, Rachel Millner, 2019, Pediatric clinics of North America.

Antimicrobial Peptides: Maintaining Sterility of the Urinary Tract

B. Becknell, J. Spencer, 2016 .

A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies.

M. Caligiuri, Yue-zhong Wu, C. Plass, 2004, Genomics.

Molecular Basis of Renal Adaptation in a Murine Model of Congenital Obstructive Nephropathy

K. McHugh, Michael E. Wilhide, B. Becknell, 2013, PloS one.

The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.

M. Caligiuri, J. Byrd, C. Hofmeister, 2010, Blood.

Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells.

M. Caligiuri, R. Davuluri, G. Marcucci, 2006, Immunity.

IFN-α-Induced Signal Transduction, Gene Expression, and Antitumor Activity of Immune Effector Cells Are Negatively Regulated by Suppressor of Cytokine Signaling Proteins1

G. Lesinski, W. Carson, V. Karpa, 2007, The Journal of Immunology.

Regulated by Suppressor of Cytokine Immune Effector Cells Are Negatively Expression , and Antitumor Activity of-Induced Signal Transduction , Gene

G. Lesinski, W. Carson, V. Karpa, 2007 .

Selective modulator of nuclear receptor PPARγ with reduced adipogenic potential ameliorates experimental nephrotic syndrome

S. Agrawal, B. Kerlin, A. Webb, 2021, bioRxiv.

Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells

G. Lesinski, W. Carson, B. Becknell, 2010, BMC Cancer.

Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells.

J. P. McCoy, M. Caligiuri, W. Linehan, 2004, Blood.

Impact of urinary tract infection on inpatient healthcare for congenital obstructive uropathy.

K. McHugh, B. VanderBrink, Patricia B. Reagan, 2012, Journal of pediatric urology.

Novel X-linked glomerulopathy is associated with a COL4A5 missense mutation in a non-collagenous interruption.

K. McBride, A. Schwaderer, B. Becknell, 2011, Kidney international.

Congenital anomalies of the kidney and urinary tract: defining risk factors of disease progression and determinants of outcomes

D. Matsell, B. Becknell, Laura Walawender, 2023, Pediatric nephrology.

Hemodialysis for Near-Fatal Sodium Phosphate Toxicity in a Child Receiving Sodium Phosphate Enemas

N. O'Brien, B. Becknell, W. Smoyer, 2014, Pediatric emergency care.

Baclofen Toxicity Responsive to Hemodialysis in a Pediatric Patient with Acute Kidney Injury

A. Schwaderer, Samantha W. Gee, B. Becknell, 2015, Journal of Pediatric Intensive Care.

Bacterial differentiation, development, and disease: mechanisms for survival.

K. Mason, S. Justice, A. Harrison, 2014, FEMS microbiology letters.

Analysis of the Ribonuclease A Superfamily of Antimicrobial Peptides in Patients Undergoing Chronic Peritoneal Dialysis

C. Ching, M. Eberl, D. Fraser, 2019, Scientific Reports.

Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract

K. McHugh, B. Becknell, J. Spencer, 2014, Kidney international.

Welcome Letter from the Director

L. Schlesinger, B. Becknell, Student Awards, 2014 .

Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine development

M. Caligiuri, K. Kaibuchi, G. Marcucci, 2003, Cell and Tissue Research.

Renal epithelial miR-205 expression correlates with disease severity in a mouse model of congenital obstructive nephropathy

K. McHugh, Michael E. Wilhide, B. Becknell, 2016, Pediatric Research.

A Review of Ribonuclease 7’s Structure, Regulation, and Contributions to Host Defense

B. Becknell, J. Spencer, 2016, International journal of molecular sciences.

Predicting outcomes in children with congenital anomalies of the kidney and urinary tract

D. Matsell, B. Becknell, M. Catapang, 2023, Pediatric Nephrology.

Hydrological simulation program: Fortran. User's manual for release 10

J. L. Kittle, Anthony S. Donigian, J. C. Imhoff, 1993 .

Repurposing HDAC inhibitors to enhance ribonuclease 4 and 7 expression and reduce urinary tract infection

N. Santoro, B. Becknell, J. Spencer, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses

M. Murtha, A. Schwaderer, B. Becknell, 2018, The Journal of clinical investigation.

Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells.

M. Caligiuri, A. Ferketich, R. Briesewitz, 2009, Blood.

The Responses of the Ribonuclease A Superfamily to Urinary Tract Infection

C. Ching, B. Becknell, J. Spencer, 2019, Front. Immunol..

Prediction of kidney failure in children with chronic kidney disease and obstructive uropathy

Jennifer N. Cooper, C. Ching, D. McLeod, 2020, Pediatric Nephrology.

Uropathogen and host responses in pyelonephritis

B. Becknell, J. Spencer, Juan de Dios Ruiz-Rosado, 2023, Nature Reviews Nephrology.

A novel mouse model for the aggressive variant of NK cell and T cell large granular lymphocyte leukemia.

M. Caligiuri, B. Blaser, H. Mao, 2010, Leukemia research.

Amplifying renal immunity: the role of antimicrobial peptides in pyelonephritis

A. Schwaderer, B. Becknell, J. Spencer, 2015, Nature Reviews Nephrology.

A Novel Human CD34(+) Subset That Constitutively Expresses the High Affinity Interleukin-2 Receptor Traffics to Lymph Nodes and Differentiates into CD56Bright Natural Killer Cells.

M. Caligiuri, G. Nuovo, A. Ferketich, 2004 .

Implications of Bacteriuria in Myelomeningocele Patients at Time of Urodynamic Testing.