K. Uegaki

发表

The role of intra-domain disulfide bonds in heat-induced irreversible denaturation of camelid single domain VHH antibodies.

Y. Hagihara, Yoko Akazawa-Ogawa, K. Uegaki, 2016, Journal of biochemistry.

Identification of the region responsible for fibril formation in the CAD domain of caspase-activated DNase.

Tsutomu Nakamura, N. Yumoto, Y. Hagihara, 2005, Journal of biochemistry.

Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.

Tsutomu Nakamura, K. Uegaki, T. Himiyama, 2019 .

Alteration of molecular assembly of peroxiredoxins from hyperthermophilic archaea

A. Shimamura, Tsutomu Nakamura, K. Uegaki, 2017 .

Segmental Isotope Labeling for Protein NMR Using Peptide Splicing

Toshio Yamazaki, Y. Kyōgoku, Y. Ishino, 1998 .

Crystal Structure of the N-terminal Domain of the Yeast General Corepressor Tup1p and Its Functional Implications*

Tsuyoshi Inoue, Y. Mukai, H. Matsumura, 2012, The Journal of Biological Chemistry.

Heterozygous inactivation of human Ku70/Ku86 heterodimer does not affect cell growth, double-strand break repair, or genome integrity.

H. Koyama, Sairei So, N. Adachi, 2006, DNA repair.

Effects of covalent dimerization on the structure and function of the carboxy-terminal fragment of neuropeptide Y.

S. Yoshikawa, S. Murase, N. Yumoto, 1997, Biochemical and biophysical research communications.

Amino acid intrinsic α‐helical propensities III: Positional dependence at several positions of C terminus

L. Serrano, M. Petukhov, N. Yumoto, 2002, Protein science : a publication of the Protein Society.

Simple one-week method to construct gene-targeting vectors: application to production of human knockout cell lines.

H. Koyama, Sairei So, N. Adachi, 2006, BioTechniques.

Detection of Brain-Derived Neurotrophic Factor (BDNF) with a Sandwich Assay on a Plasmonic Chip

H. Nakazawa, M. Umetsu, M. Kojima, 2014 .

Rapid and Sensitive Detection of Brain-Derived Neurotrophic Factor with a Plasmonic Chip

I. Kumagai, H. Nakazawa, M. Umetsu, 2013 .

Transcriptome analysis of ionic-liquid tolerant Bacillus amyloliquefaciens CMW1 and identification of a novel efflux pump

K. Uegaki, D. Aoki, A. Kurata, 2021, Biotechnology & Biotechnological Equipment.

Improved segmental isotope labeling of proteins and application to a larger protein

Y. Kyōgoku, T. Yamazaki, K. Uegaki, 1999, Journal of biomolecular NMR.

Functional analysis of the N‐terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis

Tsutomu Nakamura, K. Moriyoshi, K. Uegaki, 2022, FEBS open bio.

Crystallization and X-ray diffraction analysis of a catalytic domain of hyperthermophilic chitinase from Pyrococcus furiosus.

K. Hirata, K. Ishikawa, Tsutomu Nakamura, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of a chitin-binding domain of hyperthermophilic chitinase from Pyrococcus furiosus.

A. Nakagawa, K. Ishikawa, Tsuyoshi Inoue, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of thioredoxin peroxidase from the aerobic hyperthermophilic archaeon Aeropyrum pernix K1.

Y. Kai, K. Ishikawa, Tsuyoshi Inoue, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

BDNF Binds Its Pro-Peptide with High Affinity and the Common Val66Met Polymorphism Attenuates the Interaction

T. Hirokawa, M. Kojima, Y. Ishikawa, 2017, International journal of molecular sciences.

Improvement of the enzymatic activity of the hyperthermophilic cellulase from Pyrococcus horikoshii

H. Fukada, K. Ishikawa, Hee-Jin Kang, 2007, Extremophiles.

Application of a water jet system to the pretreatment of cellulose.

Kazuhiko Ishikawa, Tomoki Kato, K. Ishikawa, 2011, Biopolymers.

Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin‐dependent protein kinase II

Y. Shigeri, N. Yumoto, Y. Tatsu, 1998, FEBS letters.

AUSTRALIAN Halobacteria and THEIR RETINAL‐PROTEIN ION PUMPS *

Y. Mukohata, K. Ihara, K. Uegaki, 1991, Photochemistry and photobiology.

Expression, refolding, and purification of active diacetylchitobiose deacetylase from Pyrococcus horikoshii.

T. Ikegami, Tsutomu Nakamura, K. Kawasaki, 2012, Protein expression and purification.

9LBA Antitumor activity of ASP8273, an irreversible mutant selective EGFR-TKI, in NSCLC patients with tumors harboring EGFR activating mutations and T790M resistance mutation

Toshio Shimizu, M. Fukuoka, S. Morita, 2014 .

Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor.

Y. Kyōgoku, S. Nagata, H. Sakahira, 2000, Journal of molecular biology.

Alteration of molecular assembly of peroxiredoxins from hyperthermophilic archaea.

A. Shimamura, Tsutomu Nakamura, K. Uegaki, 2017, Journal of biochemistry.

Characterization of the DNA binding domain of the mouse IRF-2 protein.

T. Taniguchi, M. Shirakawa, Y. Kyōgoku, 1993, Protein engineering.

Expression from engineered Escherichia coli chromosome and crystallographic study of archaeal N,N′‐diacetylchitobiose deacetylase

T. Ikegami, T. Ueda, Tsuyoshi Inoue, 2014, The FEBS journal.

Identification of Novel Proteins in Foam Nests of the Japanese Forest Green Tree Frog, Rhacophorus arboreus

Yoshikazu Haramoto, Yoshihiro Yamamoto, T. Kinumi, 2020, Zoological Science.

Structure of the heterodimeric complex between CAD domains of CAD and ICAD

Toshio Yamazaki, S. Nagata, H. Sakahira, 2000, Nature Structural Biology.

N-Terminal Phosphorylation of HP1α Promotes Its Chromatin Binding

S. Fujiwara, J. Nakayama, D. Hamada, 2011, Molecular and Cellular Biology.

Application of chromosomal gene insertion into Escherichia coli for expression of recombinant proteins.

Tsutomu Nakamura, T. Ohmoto, D. Koma, 2018, Journal of bioscience and bioengineering.

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival

A. Ogura, T. Hirokawa, B. Lu, 2009, Molecular Brain.

Intrinsic nucleic acid-binding activity of Chp1 chromodomain is required for heterochromatic gene silencing.

Y. Nishimura, J. Nakayama, K. Uegaki, 2012, Molecular cell.

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

S. Yamawaki, C. Itami, M. Saarma, 2015, Proceedings of the National Academy of Sciences.

Screening for Stable Mutants with Amino Acid Pairs Substituted for the Disulfide Bond between Residues 14 and 38 of Bovine Pancreatic Trypsin Inhibitor (BPTI)*

Yoshihisa Hagihara, Tadayuki Imanaka, Noboru Yumoto, 2002, The Journal of Biological Chemistry.

Tertiary structure and carbohydrate recognition by the chitin-binding domain of a hyperthermophilic chitinase from Pyrococcus furiosus.

T. Ikegami, K. Ishikawa, Tsutomu Nakamura, 2008, Journal of molecular biology.

Amyloid fibril formation by the CAD domain of caspase‐activated DNase

K. Harata, Hitoshi Yamamoto, Tsutomu Nakamura, 2005, Biopolymers.

Solution structure of the IRF-2 DNA-binding domain: a novel subgroup of the winged helix-turn-helix family.

M. Swindells, T. Taniguchi, J. Furui, 1998, Structure.

Heat-induced Irreversible Denaturation of the Camelid Single Domain VHH Antibody Is Governed by Chemical Modifications

T. Ikegami, Y. Goto, Y. Hagihara, 2014, The Journal of Biological Chemistry.

Chemical Modifications the Camelid Single Domain VHH Antibody Heat-induced Irreversible Denaturation of Protein Structure and Folding :

T. Ikegami, Y. Goto, Y. Hagihara, 2014 .

Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability

Tsutomu Nakamura, Y. Kawata, K. Uegaki, 2011, The FEBS journal.

Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus– the role of conserved residues in the active site

K. Ishikawa, Tsutomu Nakamura, T. Inui, 2010, The FEBS journal.

Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site.

K. Ishikawa, Tsutomu Nakamura, T. Inui, 2010, The FEBS journal.

Structure of peroxiredoxin from the anaerobic hyperthermophilic archaeon Pyrococcus horikoshii.

Tsuyoshi Inoue, Tsutomu Nakamura, H. Matsumura, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

15N labeling method of peptides using a thioredoxin gene fusion expression system: an application to ACTH‐(1–24)

Y. Kyōgoku, M. Shimizu, K. Uegaki, 1996, FEBS letters.

Position dependence of amino acid intrinsic helical propensities II: Non‐charged polar residues: Ser, Thr, Asn, and Gln

L Serrano, Luis Serrano, M. Petukhov, 1999, Protein science : a publication of the Protein Society.

Archaerhodopsins: Novel Bacterial Proton Pumps

Y. Mukohata, K. Uegaki, Y. Sugiyama, 1991 .

Zinc ions inhibit the protein-DNA complex formation between cyanobacterial transcription factor SmtB and its recognition DNA sequences.

H. Hayashi, Y. Kyōgoku, M. Wakamatsu, 2002, Plant & cell physiology.

Stabilization of an Immunoglobulin Fold Domain by an Engineered Disulfide Bond at the Buried Hydrophobic Region*

Y. Hagihara, K. Uegaki, S. Mine, 2007, Journal of Biological Chemistry.

ASP8273, a mutant-selective irreversible EGFR inhibitor in patients (pts) with NSCLC harboring EGFR activating mutations: Preliminary results of first-in-human phase I study in Japan.

Toshio Shimizu, M. Fukuoka, S. Morita, 2015 .

Solution structure of the chitin-binding domain 1 (ChBD1) of a hyperthermophilic chitinase from Pyrococcus furiosus.

T. Ikegami, Takaaki Sato, Tsutomu Nakamura, 2006, Journal of biochemistry.

Sensing of ozone based on its quenching effect on the photoluminescence of CdSe-based core-shell quantum dots

V. Biju, Y. Shigeri, K. Uegaki, 2016, Microchimica Acta.

NMR assignment of the chitin-binding domain of a hyperthermophilic chitinase from Pyrococcus furiosus

T. Ikegami, K. Ishikawa, Tsutomu Nakamura, 2006, Journal of Biomolecular NMR.

2-Hydrazinoquinoline: A Reactive Matrix for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry to Detect Gaseous Carbonyl Compounds

F. Tani, R. Arakawa, T. Kinumi, 2016, European journal of mass spectrometry.

Reversible photoluminescence sensing of gaseous alkylamines using CdSe-based quantum dots

V. Biju, Y. Shigeri, K. Uegaki, 2017 .

Heat‐induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light‐chain REI

H. Kamikubo, M. Kataoka, Tsutomu Nakamura, 2017, The FEBS journal.

Mass Spectrometric Analysis Using Ruthenium (II)-Labeling for Identification of Glycosyl Hydrolase Product

Hitoshi Yamamoto, K. Ishikawa, Tsutomu Nakamura, 2009, Bioscience, biotechnology, and biochemistry.

Characterization and crystal structure of the thermophilic ROK hexokinase from Thermus thermophilus.

Shouhei Mine, Tsutomu Nakamura, Y. Kashima, 2012, Journal of bioscience and bioengineering.

Crystallization and preliminary crystallographic analysis of a putative glucokinase/hexokinase from Thermus thermophilus.

Y. Kashima, Tsutomu Nakamura, T. Oku, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of thioredoxin peroxidase from aerobic hyperthermophilic archaeon Aeropyrum pernix K1

Y. Kai, K. Ishikawa, Tsuyoshi Inoue, 2005, Proteins.

Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.

Tsutomu Nakamura, K. Uegaki, T. Himiyama, 2019, Journal of biochemistry.

Secondary structure and folding topology of the DNA binding domain of interferon regulatory factor 2, as revealed by NMR spectroscopy

T. Taniguchi, M. Shirakawa, Y. Kyōgoku, 1995, FEBS letters.

Archaerhodopsin-2, from Halobacterium sp. aus-2 further reveals essential amino acid residues for light-driven proton pumps.

Y. Mukohata, K. Uegaki, Y. Sugiyama, 1991, Archives of biochemistry and biophysics.

Structure of the catalytic domain of the hyperthermophilic chitinase from Pyrococcus furiosus.

K. Ishikawa, Tsutomu Nakamura, Y. Hagihara, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Intrinsic nucleic acid-binding activity of Chp1 chromodomain is required for heterochromatic gene silencing.

Y. Nishimura, J. Nakayama, K. Uegaki, 2012, Molecular cell.

Peroxiredoxin from Thermococcus kodakaraensis

Tsutomu Nakamura, K. Uegaki, T. Himiyama, 2019 .