D. Vance

发表

Stepwise Engineering of Heterodimeric Single Domain Camelid VHH Antibodies That Passively Protect Mice from Ricin Toxin*

N. Mantis, C. Shoemaker, J. Tremblay, 2013, The Journal of Biological Chemistry.

Toxin That Passively Protect Mice from Ricin H AntibodiesHSingle Domain Camelid V Stepwise Engineering of Heterodimeric Immunology :

N. Mantis, C. Shoemaker, J. Tremblay, 2013 .

High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine

S. Joshi, D. Volkin, C. R. Middaugh, 2017, Clinical and Vaccine Immunology.

Further Analysis of Multicentre Cystathionine Beta Synthase Deficiency Thrombosis Data and Metabolic Pathways Suggests Potentially Better Treatment via Improved Cysteine Supplementation, Diet, Antioxidant Supplementation, Follow-up and Testing...

D. Vance, J. VanceD, 2017 .

Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies

J. Karanicolas, M. Rudolph, D. Volkin, 2017, Proteins.

Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.

M. Rudolph, N. Mantis, C. Shoemaker, 2014, Journal of molecular biology.

Progress and challenges associated with the development of ricin toxin subunit vaccines

N. Mantis, D. Vance, 2016, Expert review of vaccines.

Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins

M. Rudolph, N. Mantis, D. Vance, 2022, The Journal of biological chemistry.

Structural analysis of toxin-neutralizing, single-domain antibodies that bridge ricin's A-B subunit interface.

M. Rudolph, N. Mantis, K. Sandvig, 2021, Journal of molecular biology.

Intracellular Neutralization of Ricin Toxin by Single Domain Antibodies Targeting the Active Site.

M. Rudolph, N. Mantis, N. Tumer, 2020, Journal of molecular biology.

Serological Analysis Identifies Consequential B Cell Epitopes on the Flexible Linker and C-Terminus of Decorin Binding Protein A (DbpA) from Borrelia burgdorferi

N. Mantis, D. Vance, J. Yates, 2022, mSphere.

Stable and potent polyvalent anthrax toxin inhibitors: raft-inspired domain formation in liposomes that contain PEGylated lipids.

R. Kane, J. Mogridge, P. Rai, 2008, Chemistry.

Enhancement of humoral immunity by the type II heat‐labile enterotoxin LT‐IIb is dependent upon IL‐6 and neutrophils

Christopher J. Greene, N. Mantis, T. D. Connell, 2016, Journal of leukocyte biology.

Biophysical characterization and immunization studies of dominant negative inhibitor (DNI), a candidate anthrax toxin subunit vaccine

Vidyashankara G. Iyer, S. Joshi, D. Volkin, 2013, Human vaccines & immunotherapeutics.

Differential Neutralizing Activities of a Single Domain Camelid Antibody (VHH) Specific for Ricin Toxin’s Binding Subunit (RTB)

N. Mantis, C. Shoemaker, D. Vance, 2014, PloS one.

Combination of two candidate subunit vaccine antigens elicits protective immunity to ricin and anthrax toxin in mice.

N. Mantis, R. Brey, D. Vance, 2015, Vaccine.

High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin

D. Volkin, N. Mantis, C. Shoemaker, 2017, Clinical and Vaccine Immunology.

High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Non-Neutralizing Single Domain Antibodies on Ricin Toxin's Enzymatic and Binding Subunits

D. Volkin, N. Mantis, C. Shoemaker, 2017 .

Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid A adjuvants.

Theodore W Randolph, C Russell Middaugh, Lilia A. Rabia, 2015, Journal of pharmaceutical sciences.

Sub-Domains of Ricin’s B Subunit as Targets of Toxin Neutralizing and Non-Neutralizing Monoclonal Antibodies

N. Mantis, D. Vance, A. Yermakova, 2012, PloS one.

Dermodialysis – Could sweating treatments for chronic renal failure substantially and feasibly improve outcomes in developing and even developed world contexts ?

D. Vance, 2016 .

The design of polyvalent therapeutics.

R. Kane, A. Joshi, P. Rai, 2008, Chemistry.

Preparation and characterization of protein-nanotube conjugates

R. Kane, J. Dordick, A. Joshi, 2009 .

Rest tremor associated with exposure to Monensin.

D. Vance, H. Blumenthal, 1988, Journal of neurology, neurosurgery, and psychiatry.

Comparative Adjuvant Effects of Type II Heat-Labile Enterotoxins in Combination with Two Different Candidate Ricin Toxin Vaccine Antigens

Christopher J. Greene, N. Mantis, T. D. Connell, 2015, Clinical and Vaccine Immunology.

Smoking – its imitative hand-oral behaviour and ingestion thereby of environmental toxins like lead ( Pb )

D. Vance, 2016 .

Polyvalency: a promising strategy for drug design.

R. Kane, A. Joshi, D. Vance, 2008, Biotechnology and bioengineering.

Slaying SARS-CoV-2 One (Single-domain) Antibody at a Time

N. Mantis, D. Vance, T. Czajka, 2020, Trends in Microbiology.

Human B Cell Epitope Map of the Lyme Disease Vaccine Antigen, OspA.

L. Cavacini, Yang Wang, N. Mantis, 2022, ACS infectious diseases.

Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi

L. Cavacini, M. Mbow, Yang Wang, 2022, bioRxiv.

A Collection of Single-Domain Antibodies that Crowd Ricin Toxin’s Active Site

M. Rudolph, D. Volkin, N. Mantis, 2018, Antibodies.

Sites of vulnerability on ricin B chain revealed through epitope mapping of toxin-neutralizing monoclonal antibodies

N. Mantis, D. Vance, Amanda Y Poon, 2020, bioRxiv.

Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin’s binding subunit

N. Mantis, D. Vance, J. Westfall, 2017, PloS one.

A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

N. Mantis, D. Vance, Yinghui Rong, 2017, Toxins.

Fine-Specificity Epitope Analysis Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies

D. Volkin, N. Mantis, D. Weis, 2018, ImmunoHorizons.

Fine Specificity Epitope Analysis by HX-MS Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies

D. Volkin, C. Russell Middaugh, N. Mantis, 2018, bioRxiv.

Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit*

M. Rudolph, N. Mantis, M. Cassidy, 2016, The Journal of Biological Chemistry.

Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit.

N. Mantis, D. Vance, 2012, Toxicon : official journal of the International Society on Toxinology.

The design of polyvalent scaffolds for targeted delivery.

David Vance, Jacob Martin, Sanket Patke, 2009, Advanced drug delivery reviews.

The Flexible Linker of Decorin Binding Protein A from Borrelia burgdorferi is a Target of Antibodies in Lyme disease

N. Mantis, D. Vance, J. Yates, 2022, bioRxiv.

Intracellular Neutralization of Ricin Toxin by Single Domain Antibodies Targeting the Active Site Pocket

M. Rudolph, N. Mantis, N. Tumer, 2019, bioRxiv.

Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.

J. Karanicolas, R. Dunbrack, M. Rudolph, 2018 .

Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity

Roland L. Dunbrack, J. Karanicolas, M. Rudolph, 2018, Protein engineering, design & selection : PEDS.

Neutralization of Typhoid Toxin by Alpaca-Derived, Single-Domain Antibodies Targeting the PltB and CdtB Subunits

N. Mantis, C. Shoemaker, J. Tremblay, 2021, Infection and immunity.

Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.

M. Rudolph, N. Mantis, C. Shoemaker, 2014, Journal of Molecular Biology.

Anti-RTA VHH antibody

J. Karanicolas, R. Dunbrack, M. Rudolph, 2018 .

Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi

L. Cavacini, Yang Wang, N. Mantis, 2023, Proteins.

Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies

J. Karanicolas, D. Volkin, N. Mantis, 2017, Proteins.

Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi

L. Cavacini, M. Mbow, Yang Wang, 2023, mBio.

Structural Elucidation of a Protective B cell Epitope on Outer Surface Protein C (OspC) of 2 the Lyme

N. Mantis, M. Ejemel, D. Vance, 2022 .

Structural analysis of nested neutralizing and non‐neutralizing B cell epitopes on ricin toxin's enzymatic subunit

M. Rudolph, N. Mantis, C. Shoemaker, 2016, Proteins.

A refined human linear B cell epitope map of Outer surface protein C (OspC) from the Lyme disease spirochete, Borreliella burgdorferi

N. Mantis, D. Vance, Michael J Rudolph, 2024, bioRxiv.