D. Jacques

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Chapter viii calcitonin gene-related peptide (cgrp), amylin and adrenomedullin: anatomical localization and biological functions in the mammalian and human brains

R. Quirion, Y. Dumont, D. Jacques, 2000 .

Taurine and cardiac disease: state of the art and perspectives.

D. Jacques, G. Bkaily, Ashley Jazzar, 2020, Canadian journal of physiology and pharmacology.

Neuropeptide y receptor types in the mammalian brain: Species differences and status in the human central nervous system

R. Quirion, Y. Dumont, D. Jacques, 1997 .

Characterization of neuropeptide Y receptor subtypes in the normal human brain, including the hypothalamus

R. Quirion, A. Fournier, Y. Dumont, 1997, Neuroscience.

BIIE0246, a potent and highly selective non‐peptide neuropeptide Y Y2 receptor antagonist

E. Hamel, R. Quirion, A. Cadieux, 2000, British journal of pharmacology.

Interactions of multiple signaling pathways in neuropeptide Y-mediated bimodal vascular smooth muscle cell growth.

J. Kitlinska, Z. Zukowska, D. Jacques, 2008, Canadian journal of physiology and pharmacology.

Expression of the neuropeptide Y Y1 receptor mRNA in the human brain: an in situ hybridization study

R. Quirion, S. Shen, Y. Dumont, 1996, Neuroreport.

Species differences in the expression and distribution of the neuropeptide Y Y1, Y2, Y4, and Y5 receptors in rodents, guinea pig, and primates brains

R. Quirion, Y. Dumont, D. Jacques, 1998, The Journal of comparative neurology.

Receptors and ionic transporters in nuclear membranes: new targets for therapeutical pharmacological interventions.

D. Jacques, G. Bkaily, Lena Ahmarani, 2012, Canadian journal of physiology and pharmacology.

Presence of tubular and reticular structures in the nucleus of human vascular smooth muscle cells.

D. Jacques, G. Bkaily, Levon Avedanian, 2011, Journal of molecular and cellular cardiology.

Nuclear membrane receptors for ET-1 in cardiovascular function

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Increase of NOX3 in heart failure of hereditary cardiomyopathy.

D. Jacques, G. Bkaily, Wassim Najibeddine, 2019, Canadian journal of physiology and pharmacology.

Difference in the response to angiotensin II between left and right ventricular endocardial endothelial cells.

D. Jacques, G. Bkaily, Johny Al-Khoury, 2017, Canadian journal of physiology and pharmacology.

Vascular smooth muscle remodeling in health and disease.

D. Jacques, G. Bkaily, Ashley Jazzar, 2020, Canadian journal of physiology and pharmacology.

Insulin-Induced Cardiomyocytes Hypertrophy That Is Prevented by Taurine via β-alanine-Sensitive Na+-Taurine Symporter

D. Jacques, G. Bkaily, Ashley Jazzar, 2021, Nutrients.

Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction

R. Lecomte, S. Takai, M. Lepage, 2018, Front. Pharmacol..

ETA receptors are present in human aortic vascular endothelial cells and modulate intracellular calcium.

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2010, Canadian journal of physiology and pharmacology.

Nuclear Membranes ETB Receptors Mediate ET-1–induced Increase of Nuclear Calcium in Human Left Ventricular Endocardial Endothelial Cells

D. Jacques, G. Bkaily, Alexandre Normand, 2015, Journal of cardiovascular pharmacology.

Nuclear membrane R-type calcium channels mediate cytosolic ET-1-induced increase of nuclear calcium in human vascular smooth muscle cells.

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2015, Canadian journal of physiology and pharmacology.

Discrete distribution of the neuropeptide Y Y5 receptor gene in the human brain: an in situ hybridization study.

R. Quirion, S. Shen, D. Jacques, 1998, Brain research. Molecular brain research.

Three types of slow inward currents as distinguished by melittin in 3-day-old embryonic heart.

A. Sculptoreanu, N. Sperelakis, D. Jacques, 1988, Canadian journal of physiology and pharmacology.

Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells.

Sama F. Sleiman, S. Choufani, C. Asselin, 2003, Canadian journal of physiology and pharmacology.

Na(+)-H(+) exchanger inhibitor prevents early death in hereditary cardiomyopathy.

N. Beier, W. Scholz, M. Chahine, 2015, Canadian journal of physiology and pharmacology.

ETA and ETB receptors contribute to neuropeptide Y-induced secretion of endothelin-1 in right but not left human ventricular endocardial endothelial cells

D. Jacques, S. Magder, G. Bkaily, 2016, Neuropeptides.

Differences in neuropeptide Y-induced secretion of endothelin-1 in left and right human endocardial endothelial cells

D. Jacques, S. Magder, G. Bkaily, 2012, Neuropeptides.

Endocardial endothelial cell hypertrophy takes place during the development of hereditary cardiomyopathy

D. Jacques, G. Bkaily, 2019, Molecular and Cellular Biochemistry.

High salt-induced hypertrophy of human vascular smooth muscle cells associated with a decrease in glycocalyx.

D. Jacques, G. Bkaily, Yanick Simon, 2018, Journal of molecular and cellular cardiology.

Angiotensin II induces apoptosis of human right and left ventricular endocardial endothelial cells by activating the AT2 receptor 1.

D. Jacques, G. Bkaily, Chantale Provost, 2019, Canadian journal of physiology and pharmacology.

Angiotensin II induces apoptosis of human right and left ventricular endocardial endothelial cells by activating the AT2 receptor

D. Jacques, G. Bkaily, Chantale Provost, 2019 .

Neuropeptide Y and its receptors in ventricular endocardial endothelial cells.

D. Jacques, S. Magder, G. Bkaily, 2017, Canadian journal of physiology and pharmacology.

Neuropeptide Y (NPY) and NPY receptors in the cardiovascular system: implication in the regulation of intracellular calcium.

D. Jacques, Dima Abdel-Samad, 2007, Canadian journal of physiology and pharmacology.

Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium.

A. Beck‐Sickinger, A. Fournier, G. Pelletier, 2003, Canadian journal of physiology and pharmacology.

NPY and NPY receptors: presence, distribution and roles in the regulation of the endocardial endothelium and cardiac function.

D. Jacques, C. Perreault, S. Sader, 2006, EXS.

Roles of nuclear NPY and NPY receptors in the regulation of the endocardial endothelium and heart function.

D. Jacques, Chantale Provost, C. Perreault, 2006, Canadian journal of physiology and pharmacology.

NPY, ET-1, and Ang II nuclear receptors in human endocardial endothelial cells.

D. Jacques, Chantale Provost, C. Perreault, 2006, Canadian journal of physiology and pharmacology.

Draft Increase of NOX 3 in heart failure of hereditary cardiomyopathy

D. Jacques, G. Bkaily, Wassim Najibeddine, 2019 .

Receptors and Channels of Nuclear Envelope Membranes as a New Target for Drug Action

D. Jacques, G. Bkaily, P. D. Juste, 2004 .

Nuclear membranes GPCRs: implication in cardiovascular health and diseases.

D. Jacques, G. Bkaily, Johny Al-Khoury, 2014, Current vascular pharmacology.

Modulation of intracellular Ca2+ via L-type calcium channels in heart cells by the autoantibody directed against the second extracellular loop of the alpha1-adrenoceptors.

R. Sukarieh, N. El-Bizri, D. Jacques, 2003, Canadian journal of physiology and pharmacology.

Modulation of intracellular Ca 2+ via L-type calcium channels in heart cells by the autoantibody directed against the second extracellular loop of

R. Sukarieh, N. El-Bizri, D. Jacques, 2003 .

Role of insulin on jejunal PepT1 expression and function regulation in diabetic male and female rats.

A. Sibai, A. Bikhazi, D. Jacques, 2010, Canadian journal of physiology and pharmacology.

Nitric oxide relaxes the vascular smooth muscle independently of endothelin-1- and U46619-induced intracellular increase of calcium.

D. Jacques, H. Shbaklo, G. Bkaily, 2000, Journal of cardiovascular pharmacology.

Role of the Slow Sodium Channel in Hereditary Cardiomyopathy

G. Jasmin, D. Jacques, G. Bkaily, 1996 .

Neuropeptide Y induced increase of cytosolic and nuclear Ca2+ in heart and vascular smooth muscle cells.

N. El-Bizri, D. Jacques, H. Shbaklo, 2000, Canadian journal of physiology and pharmacology.

Endothelin-1 regulates cytosolic and nuclear Ca2+ in human endocardial endothelium.

S. Choufani, D. Jacques, D. Charest, 2000, Journal of Cardiovascular Pharmacology.

Physical contact between human vascular endothelial and smooth muscle cells modulates cytosolic and nuclear calcium homeostasis.

D. Jacques, S. Magder, G. Bkaily, 2018, Canadian journal of physiology and pharmacology.

Whole-cell and nuclear NADPH oxidases levels and distribution in human endocardial endothelial, vascular smooth muscle, and vascular endothelial cells.

D. Jacques, G. Bkaily, Lena Ahmarani, 2013, Canadian journal of physiology and pharmacology.

Extracelluar and intracellular tumor necrosis factor alpha modulates cytosolic and nuclear calcium in human cardiovascular cells

D. Jacques, G. Bkaily, M. Chamoun, 2019 .

Hypotension in hereditary cardiomyopathy

D. Jacques, G. Bkaily, J. Al-Khoury, 2022, Pflügers Archiv - European Journal of Physiology.

Apparent affinity and potency of BIBP3226, a non-peptide neuropeptide Y receptor antagonist, on purported neuropeptide Y Y1, Y2 and Y3 receptors.

R. Quirion, A. Cadieux, Y. Dumont, 1995, European journal of pharmacology.

Angiotensin II and its receptors in human endocardial endothelial cells: role in modulating intracellular calcium.

D. Jacques, C. Perreault, S. Sader, 2003, Canadian journal of physiology and pharmacology.

Angiotensin II-induced increase of T-type Ca2+ current and decrease of L-type Ca2+ current in heart cells

A. Sculptoreanu, K. Hazzouri, D. Jacques, 2005, Peptides.

The distribution and density of ET-1 and its receptors are different in human right and left ventricular endocardial endothelial cells

D. Jacques, C. Perreault, Magda Descorbeth, 2005, Peptides.

The use of confocal microscopy in the investigation of cell structure and function in the heart, vascular endothelium and smooth muscle cells

François Belzile, P. Pothier, F. Belzile, 1997, Molecular and Cellular Biochemistry.

Bradykinin induced a positive chronotropic effect via stimulation of T- and L-type calcium currents in heart cells.

R. Sukarieh, N. El-Bizri, D. Jacques, 2003, Canadian journal of physiology and pharmacology.

Morphological and Functional Remodeling of Vascular Endothelium in Cardiovascular Diseases

D. Jacques, G. Bkaily, 2023, International journal of molecular sciences.

Role of endothelin-1 and its receptors, ETA and ETB, in the survival of human vascular endothelial cells.

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2017, Canadian journal of physiology and pharmacology.

High Na+ Salt Diet and Remodeling of Vascular Smooth Muscle and Endothelial Cells

D. Jacques, G. Bkaily, Ashley Jazzar, 2021, Biomedicines.

Endocardial endothelial cell hypertrophy takes place during the development of hereditary cardiomyopathy

D. Jacques, G. Bkaily, 2019, Molecular and Cellular Biochemistry.

Angiotensin II receptors' modulation of calcium homeostasis in human vascular endothelial cells.

M. Kamal, D. Jacques, G. Bkaily, 2017, Canadian journal of physiology and pharmacology.

A new paradigm: calcium independent and caveolae internalization dependent release of nitric oxide by the endothelial nitric oxide synthase.

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2006, Circulation research.

G-protein-coupled receptors, channels, and Na+–H+ exchanger in nuclear membranes of heart, hepatic, vascular endothelial, and smooth muscle cellsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.

S. Choufani, S. Chemtob, D. Jacques, 2006 .

Bradykinin activates R-, T-, and L-type Ca2+ channels and induces a sustained increase of nuclear Ca2+ in aortic vascular smooth muscle cells.

P. Pothier, D. Jaalouk, D. Jacques, 1997, Canadian journal of physiology and pharmacology.

Presence of functional endothelin-1 receptors in nuclear membranes of human aortic vascular smooth muscle cells.

S. Choufani, N. El-Bizri, D. Jacques, 2000, Journal of cardiovascular pharmacology.

Nuclear membrane receptors and channels as targets for drug development in cardiovascular diseases.

D. Jacques, G. Bkaily, L. Avedanian, 2009, Canadian journal of physiology and pharmacology.

Intracellular Free Calcium Measurement Using Confocal Imaging.

D. Jacques, G. Bkaily, Yanick Simon, 2017, Methods in molecular biology.

Extracellular and intracellular tumor necrosis factor alpha modulates cytosolic and nuclear calcium in human cardiovascular cells 1.

D. Jacques, G. Bkaily, M. Chamoun, 2019, Canadian journal of physiology and pharmacology.

Immunofluorescence revealed the presence of NHE-1 in the nuclear membranes of rat cardiomyocytes and isolated nuclei of human, rabbit, and rat aortic and liver tissues.

K. Hazzouri, D. Jacques, F. Gobeil, 2004, Canadian journal of physiology and pharmacology.

A tetrodotoxin‐ and Mn2+‐insensitive Na+ current in Duchenne muscular dystrophy

D. Jacques, G. Bkaily, T. Yamamoto, 1990, Muscle & nerve.

Apamin, a highly potent blocker of the TTX- and Mn2(+)-insensitive fast transient Na+ current in young embryonic heart.

A. Sculptoreanu, N. Sperelakis, D. Jacques, 1991, Journal of molecular and cellular cardiology.

Chapter IX Neuropeptide Y, peptide YY and pancreatic polypeptide receptor proteins and mRNAs in mammalian brains

R. Quirion, H. Herzog, Y. Dumont, 2000 .

Na+-H+ exchanger and proton channel in heart failure associated with Becker and Duchenne muscular dystrophies.

D. Jacques, G. Bkaily, 2017, Canadian journal of physiology and pharmacology.

NHE-1-dependent intracellular sodium overload in hypertrophic hereditary cardiomyopathy: prevention by NHE-1 inhibitor.

N. Beier, W. Scholz, M. Chahine, 2005, Journal of molecular and cellular cardiology.

Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors

K. Hazzouri, N. El-Bizri, D. Jacques, 2005, Peptides.

Membrane Physiopathology in Hereditary Cardiomyopathy

D. Jacques, G. Bkaily, 1994 .

Short-Communication: Short-Term Treatment with Taurine Prevents the Development of Cardiac Hypertrophy and Early Death in Hereditary Cardiomyopathy of the Hamster and Is Sex-Dependent

A. Khalil, D. Jacques, G. Bkaily, 2022, Nutrients.

Endocardial endothelial cell hypertrophy takes place during the development of hereditary cardiomyopathy

D. Jacques, G. Bkaily, 2018, Molecular and Cellular Biochemistry.

Draft 1 Na +-H + EXCHANGER AND PROTON CHANNEL IN HEART FAILURE ASSOCIATED WITH BECKER AND DUCHENNE MUSCULAR DYSTROPHY

D. Jacques, G. Bkaily, 2017 .

ETB receptor dependent alteration in aortic responses to ET-1 in the cardiomyopathic hamster.

M. Chahine, D. Jacques, G. Bkaily, 2006, Canadian journal of physiology and pharmacology.

Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster.

G. Jasmin, M. Chahine, D. Jacques, 2003, Canadian journal of physiology and pharmacology.

Nutrition as a determinant of successful aging: description of the Quebec longitudinal study Nuage and results from cross-sectional pilot studies.

Pierrette Gaudreau, Hélène Payette, Katherine Gray-Donald, 2007, Rejuvenation research.

Taurine indirectly increases [Ca]i by inducing Ca2+ influx through the Na+-Ca2+ exchanger

P. Pothier, D. Jaalouk, E. Cragoe, 1998, Molecular and Cellular Biochemistry.

NPY regulates human endocardial endothelial cell function

D. Jacques, C. Perreault, Dima Abdel-Samad, 2007, Peptides.

Activation of sarcolemma and nuclear membranes ET-1 receptors regulates transcellular calcium levels in heart and vascular smooth muscle cells.

S. Choufani, M. Kamal, D. Jacques, 2003, Canadian journal of physiology and pharmacology.

Calcium Homeostasis, Transporters, and Blockers in Health and Diseases of the Cardiovascular System

D. Jacques, G. Bkaily, 2023, International journal of molecular sciences.

Nitric oxide and reactive oxygen species in the nucleus revisited.

D. Jacques, F. Gobeil, G. Bkaily, 2010, Canadian journal of physiology and pharmacology.

Apamin, a highly potent fetal L-type Ca2+ current blocker in single heart cells.

A. Sculptoreanu, D. Jacques, G. Bkaily, 1992, The American journal of physiology.

Early fetal like slow Na+ current in heart cells of cardiomyopathic hamster

G. Jasmin, Ghassan Bkaily, Danielle Jacques, 1997, Molecular and Cellular Biochemistry.

Increases of T-type Ca2+ current in heart cells of the cardiomyopathic hamster

A. Sculptoreanu, G. Jasmin, D. Jacques, 2004, Molecular and Cellular Biochemistry.

Increases of T-type Ca2+ current in heart cells of the cardiomyopathic hamster.

A. Sculptoreanu, G. Jasmin, D. Jacques, 1997 .

G-protein-coupled receptors, channels, and Na+-H+ exchanger in nuclear membranes of heart, hepatic, vascular endothelial, and smooth muscle cells.

S. Choufani, S. Chemtob, D. Jacques, 2006, Canadian Journal of Physiology and Pharmacology.

Nonpeptidic antagonists of ETA and ETB receptors reverse the ET-1-induced sustained increase of cytosolic and nuclear calcium in human aortic vascular smooth muscle cells.

S. Choufani, D. Jacques, G. Bkaily, 2008, Canadian journal of physiology and pharmacology.

Use of confocal microscopy to investigate cell structure and function.

P. Pothier, D. Jacques, G. Bkaily, 1999, Methods in enzymology.

Endothelin-1 and insulin activate the steady-state voltage dependent R-type Ca2+ channel in aortic smooth muscle cells via a pertussis toxin and cholera toxin sensitive G-protein

P. Pothier, D. Jaalouk, D. Jacques, 1998, Molecular and Cellular Biochemistry.

Atrial natriuretic factor blocks the high-threshold Ca2+ current and increases K+ current in fetal single ventricular cells.

A. Sculptoreanu, D. Jacques, G. Bkaily, 1993, Journal of molecular and cellular cardiology.

Angiotensin II increases Isi and blocks IK in single aortic cell of rabbit

A. Sculptoreanu, N. Sperelakis, M. Chahine, 1988, Pflügers Archiv - European Journal of Physiology.

Effect of diabetes mellitus and insulin on the regulation of the PepT 1 symporter in rat jejunum.

A. Bikhazi, D. Jacques, David E. Smith, 2004, Molecular pharmaceutics.

Flaxseed as an Anticardiotoxicity Agent in Breast Cancer Therapy.

D. Jacques, G. Bkaily, 2020, The Journal of nutrition.

Na(+)-H(+) exchanger inhibitor prevents early death in hereditary cardiomyopathy.

N. Beier, W. Scholz, M. Chahine, 2015, Canadian journal of physiology and pharmacology.

Bay K 8644 induce enhancement of K+ current in both single heart cell and smooth muscle cell

N. Sperelakis, J. Renaud, D. Jacques, 1989, Molecular and Cellular Biochemistry.

L-type calcium channel antagonists and suppression of expression of plasminogen receptors: is the missing link the L-type calcium channel?

D. Jacques, G. Bkaily, 2009, Circulation Research.

High salt-induced morphological and glycocalyx remodeling of human vascular smooth muscle cells is reversible but induces a high sodium salt-like sensitive memory.

D. Jacques, G. Bkaily, Yanick Simon, 2023, Canadian Journal of Physiology and Pharmacology.

ETA receptors are present in human aortic vascular endothelial cells and modulate intracellular calcium.

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2010, Canadian journal of physiology and pharmacology.

A new paradigm: calcium independent and caveolae internalization dependent release of nitric oxide by the endothelial nitric oxide synthase.

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2006, Circulation research.

Dependent Release of Nitric Oxide by the Endothelial Nitric Oxide Synthase A New Paradigm : Calcium Independent and Caveolae Internalization

D. Jacques, G. Bkaily, P. D'Orléans-Juste, 2012 .