Tobias Kroon

发表

In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects

J. Garmey, A. Klibanov, K. Kelly, 2020, Theranostics.

Feedback modeling of non-esterified fatty acids in obese Zucker rats after nicotinic acid infusions

L. Peletier, C. Ahlström, J. Gabrielsson, 2013, Journal of Pharmacokinetics and Pharmacodynamics.

The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis

J. Boucher, M. Sörhede-Winzell, N. Oakes, 2022, Journal of lipid research.

PPARγ and PPARα synergize to induce robust browning of white fat in vivo

P. Gennemark, D. Nilsson, J. Boucher, 2020, Molecular metabolism.

Dosing profile profoundly influences nicotinic acid’s ability to improve metabolic control in rats

N. Oakes, J. Gabrielsson, Tobias Kroon, 2015, Journal of Lipid Research.

BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice

U. Smith, F. Bosch, A. Hammarstedt, 2019, Molecular metabolism.

Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats[S]

T. Baccega, N. Oakes, J. Gabrielsson, 2016, Journal of Lipid Research.

Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH

J. Boucher, J. Oscarsson, Ulf Smith, 2022, Frontiers in Endocrinology.

Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments

M. Jirstrand, R. Andersson, J. Almquist, 2017, Journal of Pharmacokinetics and Pharmacodynamics.

Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats

J. Boucher, N. Oakes, Tobias Kroon, 2022, Science Translational Medicine.

Optimizing nicotinic acid delivery for durable antilipolysis and improved metabolic control

Tobias Kroon, 2016 .

Feedback modeling of non-esterified fatty acids in obese Zucker rats after nicotinic acid infusions

L. Peletier, C. Ahlström, J. Gabrielsson, 2013, Journal of Pharmacokinetics and Pharmacodynamics.

Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments

M. Jirstrand, R. Andersson, J. Almquist, 2017, Journal of Pharmacokinetics and Pharmacodynamics.

1881-P: The SGLT2 Inhibitor Dapagliflozin Improves Glucose Control and Enhances Liver Fatty Acid Oxidation and Ketone Body Formation in Insulin Resistant Obese Zucker Rats

J. Boucher, M. S. Winzell, Tobias Kroon, 2019, Diabetes.