Jason M. Ridlon

发表

The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View

Fiona Ginty, Mark P. Styczynski, Ilya Shmulevich, 2020, Trends in cancer.

Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells

Matthew E. Hudson, John W. Erdman, S. Devendran, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Bile acids and the gut microbiome

P. Hylemon, J. Bajaj, J. Ridlon, 2014, Current opinion in gastroenterology.

Bile salt biotransformations by human intestinal bacteria Published, JLR Papers in Press, November 18, 2005.

Dae-Joong Kang, P. Hylemon, J. Ridlon, 2006, Journal of Lipid Research.

Consequences of bile salt biotransformations by intestinal bacteria

P. Hylemon, J. Ridlon, Daejoong Kang, 2016, Gut microbes.

Effects of taurocholic acid metabolism by gut bacteria: A controlled feeding trial in adult African American subjects at elevated risk for colorectal cancer

S. Freels, H. Gaskins, P. Wolf, 2020, Contemporary clinical trials communications.

Taurocholic acid metabolism by gut microbes and colon cancer

H. Gaskins, P. Wolf, J. Ridlon, 2016, Gut microbes.

Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesit

Beatriz Peñalver Bernabé, L. Davidson, R. Chapkin, 2023, Trials.

Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium

P. Hylemon, J. Ridlon, Jason M. Ridlon, 2012, Journal of Lipid Research.

Modulation of the Metabiome by Rifaximin in Patients with Cirrhosis and Minimal Hepatic Encephalopathy

Andmorgan R. Fisher, H. Rangwala, P. Hylemon, 2013, PloS one.

A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity

N. Segata, G. Suen, F. Cava, 2020, Nature Communications.

Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes

Karthik Anantharaman, H. Nittono, J. Alves, 2022, bioRxiv.

Cirrhosis, bile acids and gut microbiota

J. Alves, P. Hylemon, J. Bajaj, 2013, Gut microbes.

Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.

H. Nittono, P. Hylemon, J. Bajaj, 2013, Journal of Hepatology.

Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature.

P. Hylemon, J. Ridlon, Phillip B Hylemon, 2005, Journal of clinical gastroenterology.

Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine

J. Rawls, Colin R. Lickwar, J. Ridlon, 2020, Science Advances.

Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome

E. Bayer, Z. Wawrzak, I. Cann, 2022, The Journal of biological chemistry.

Unraveling a complex relationship

J. Alves, P. Hylemon, J. Bajaj, 2013 .

Innovative and Emerging Technologies in GI Physiology and Disease Colonic inflammation and secondary bile acids in alcoholic cirrhosis

H. Nittono, Runping Liu, P. Hylemon, 2014 .

Linkage of gut microbiome with cognition in hepatic encephalopathy.

P. Hylemon, J. Bajaj, J. Ridlon, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Diversity and distribution of sulfur metabolic genes in the human gut microbiome and their association with colorectal cancer

Karthik Anantharaman, H. Gaskins, P. Wolf, 2022, Microbiome.

Diversity and distribution of sulfur metabolism in the human gut microbiome and its association with colorectal cancer

Karthik Anantharaman, H. Gaskins, P. Wolf, 2021, bioRxiv.

Conceptualizing the Vertebrate Sterolbiome

J. Ridlon, Jason M. Ridlon, 2020, Applied and Environmental Microbiology.

Glucocorticoids and gut bacteria: “The GALF Hypothesis” in the metagenomic era

J. Ridlon, Jason M. Ridlon, D. Morris, 2017, Steroids.

Clostridium scindens baiCD and baiH genes encode stereo-specific 7α/7β-hydroxy-3-oxo-Δ4-cholenoic acid oxidoreductases

P. Hylemon, J. Ridlon, Daejoong Kang, 2008 .

ENZYMOLOGY AND MOLECULAR BIOLOGY OF BILE ACID 7alpha- AND 7beta-DEHYDROXYLATION BY THE INTESTINAL BACTERIA CLOSTRIDIUMSCINDENS AND CLOSTRIDIUM HYLEMONAE

J. Ridlon, Jason M. Ridlon, 2008 .

Microbial Hydroxysteroid Dehydrogenases: From Alpha to Omega

J. Ridlon, Jason M. Ridlon, Heidi L. Doden, 2021, Microorganisms.

Completion of the gut microbial epi-bile acid pathway

Karthik Anantharaman, H. Gaskins, P. Wolf, 2020, Gut microbes.

Identification and characterization of a gene encoding NADP(H)-dependent bile acid 12β-hydroxysteroid dehydrogenase from Clostridium paraputrificum ATCC 25780

J. Ridlon, Jason M. Ridlon, Heidi L. Doden, 2020, bioRxiv.

Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria

S. Devendran, Lindsey K. Ly, J. Ridlon, 2018, Applied and Environmental Microbiology.

The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice

C. Trautwein, B. Stecher, M. von Bergen, 2020, Gut microbes.

A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine.

Yue-qin Tang, P. Hylemon, Guangji Wang, 2015, Molecular bioSystems.

Correction: A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine.

Yue-qin Tang, P. Hylemon, Guangji Wang, 2015, Molecular bioSystems.

Gut Microbiota, Cirrhosis, and Alcohol Regulate Bile Acid Metabolism in the Gut

P. Hylemon, J. Bajaj, J. Ridlon, 2015, Digestive Diseases.

Effect of imidacloprid ingestion on immune responses to porcine reproductive and respiratory syndrome virus

Rodney W. Johnson, A. Steelman, Jason M. Ridlon, 2018, Scientific Reports.

Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis

Mitchell D. Miller, I. Wilson, S. Lesley, 2016, Proteins.

Bile acid oxidation by Eggerthella lenta strains C592 and DSM 2243T

Alvaro G. Hernandez, I. Cann, C. Fields, 2018, Gut microbes.

Targeted Synthesis and Characterization of a Gene Cluster Encoding NAD(P)H-Dependent 3α-, 3β-, and 12α-Hydroxysteroid Dehydrogenases from Eggerthella CAG:298, a Gut Metagenomic Sequence

I. Cann, S. Devendran, J. Ridlon, 2018, Applied and Environmental Microbiology.

Infection with Bacteroides Phage BV01 Alters the Host Transcriptome and Bile Acid Metabolism in a Common Human Gut Microbe

P. Degnan, Lindsey K. Ly, J. Ridlon, 2020, Cell reports.

The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics

J. Bajaj, J. Ridlon, Jason M. Ridlon, 2015, Acta pharmaceutica Sinica. B.

Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704.

J. Alves, P. Hylemon, S. Devendran, 2018, Biochimica et biophysica acta. Molecular and cell biology of lipids.

The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

Alvaro G. Hernandez, H. Nittono, G. Chlipala, 2020, Gut microbes.

Bacteria on steroids: the enzymatic mechanism of an NADH-dependent dehydrogenase that regulates the conversion of cortisol to androgen in the gut microbiome

Rafael C. Bernardi, Marcelo C. R. Melo, Z. Luthey-Schulten, 2020, bioRxiv.

Infection with novel Bacteroides phage BV01 alters host transcriptome and bile acid metabolism in a common human gut microbe

P. Degnan, Lindsey K. Ly, J. Ridlon, 2020, bioRxiv.

Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from Bifidobacterium adolescentis strain L2-32

Z. Wawrzak, I. Cann, S. Devendran, 2019, The Journal of Biological Chemistry.

Bile Acids, Gut Microbes, and the Neighborhood Food Environment—a Potential Driver of Colorectal Cancer Health Disparities

H. Gaskins, Doratha A. Byrd, P. Wolf, 2022, mSystems.

Metabolism of hydrogen gases and bile acids in the gut microbiome

P. Hylemon, J. Ridlon, Jason M. Ridlon, 2018, FEBS letters.

Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation.

Masoumeh Sikaroodi, Patrick M Gillevet, Kalyani Daita, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers

Michael B. Mundy, S. Thibodeau, O. Reséndis-Antonio, 2018, Genome Medicine.

Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens

G. Buck, J. Alves, P. Hylemon, 2013, Journal of Lipid Research.

Gut feelings about bacterial steroid-17,20-desmolase

Lindsey K. Ly, J. Ridlon, Jason M. Ridlon, 2021, Molecular and Cellular Endocrinology.

Clostridium scindens ATCC 35704: Integration of Nutritional Requirements, the Complete Genome Sequence, and Global Transcriptional Responses to Bile Acids

Alvaro G. Hernandez, C. Fields, S. Devendran, 2019, Applied and Environmental Microbiology.

Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271.

P. Hylemon, J. Ridlon, Daejoong Kang, 2010, Anaerobe.

A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy

S. Taylor-Robinson, P. Fatouros, C. Schubert, 2012, Metabolic Brain Disease.

Development of methods for the detection and quantification of 7alpha-dehydroxylating clostridia, Desulfovibrio vulgaris, Methanobrevibacter smithii, and Lactobacillus plantarum in human feces.

P. Hylemon, J. Ridlon, Jason M. Ridlon, 2005, Clinica chimica acta; international journal of clinical chemistry.

Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.

H. Nittono, P. Hylemon, J. Bajaj, 2013, Journal of hepatology.

Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation.

P. Hylemon, J. Bajaj, P. Gillevet, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs

K. Swanson, S. Devendran, J. Suchodolski, 2018, British Journal of Nutrition.

Gut Microbiota, Cirrhosis, and Alcohol Regulate Bile Acid Metabolism in the Gut

P. Hylemon, J. Bajaj, Daejoong Kang, 2015, Digestive Diseases.

C URRENT OPINION Bile acids and the gut microbiome

P. Hylemon, J. Bajaj, J. Ridlon, 2014 .

Complete genome sequence of the archetype bile acid 7α-dehydroxylating bacterium, Clostridium scindens VPI12708, isolated from human feces, circa 1980

Alvaro G. Hernandez, J. Alves, S. Daniel, 2023, Microbiology resource announcements.

Feeding mode influences dynamic gut microbiota signatures and affects susceptibility to anti-CD3 mAb-induced intestinal injury in neonatal mice.

S. Swaminathan, P. Chou, Jason M. Ridlon, 2022, American journal of physiology. Gastrointestinal and liver physiology.

Berberine alters gut microbial function through modulation of bile acids

H. Nittono, G. Chlipala, H. Gaskins, 2020, BMC Microbiology.

Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis

Mitchell D. Miller, I. Wilson, S. Lesley, 2016, Proteins: Structure, Function, and Bioinformatics.

The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology

H. Gaskins, J. Ridlon, S. Daniel, 2023, Journal of lipid research.

The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase[S]

S. Devendran, J. Ridlon, Jason M. Ridlon, 2018, Journal of Lipid Research.

Another renaissance for bile acid gastrointestinal microbiology.

Jason M. Ridlon, H. R. Gaskins, 2024, Nature reviews. Gastroenterology & hepatology.

The Cancer Microbiome: Distinguishing Direct and Indirect Effects The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View Requires a Systemic View you.

Heather H Gustafson, B. Webb-Robertson, J. Caporaso, 2021 .