David Y. Chiang

发表

Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation

Na Li, Niels Voigt, Matthias Karck, 2014, Circulation.

Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation

A. Heck, S. Lehnart, X. Wehrens, 2020, Circulation.

Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model

S. Nattel, X. Wehrens, D. Dobrev, 2014, Circulation.

Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases.

X. Wehrens, David Y. Chiang, A. Landstrom, 2014, Cardiovascular research.

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.

M. Ackerman, X. Wehrens, Long-Sheng Song, 2013, Cardiovascular research.

Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs

R. Redon, N. Galjart, F. Charpentier, 2021, Circulation research.

A Contributing Factor to Atrial Fibrillation

X. Wehrens, David Y. Chiang, 2013 .

Chronic exercise: a contributing factor to atrial fibrillation?

X. Wehrens, David Y. Chiang, Na Li, 2013, Journal of the American College of Cardiology.

Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy

Mark E. Anderson, X. Wehrens, Shuyi Cao, 2018, Circulation. Arrhythmia and electrophysiology.

Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression

A. Heck, X. Wehrens, M. Fitzpatrick, 2018, Circulation.

Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases.

Yanbin Zhao, M. Yamagishi, Micah L. Burch, 2020, Cardiovascular research.

with mitral stenosis MicroRNA expression signature in atrial fibrillation

S. Zhong, Yunfu Sun, X. Wehrens, 2015 .

The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2.

A. Karma, K. Moshal, C. Macrae, 2020, The Journal of biological chemistry.

Atrial Standstill in the Pediatric Population

D. Milewicz, E. Jaeggi, Douglas Y Mah, 2022, JACC: Clinical Electrophysiology.

Wounds That Would Not Heal: Pyoderma Gangrenosum.

S. Granter, J. Merola, A. Mostaghimi, 2017, The American journal of medicine.

Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation

X. Wehrens, J. Noebels, D. Dobrev, 2015, Basic Research in Cardiology.

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

R. Redon, K. Strauch, P. Lambiase, 2022, Nature Genetics.

Loss of MicroRNA-106b-25 Cluster Promotes Atrial Fibrillation by Enhancing Ryanodine Receptor Type-2 Expression and Calcium Release

J. Neilson, X. Wehrens, D. Dobrev, 2014, Circulation. Arrhythmia and electrophysiology.

Phosphorylation-Dependent Interactome of Ryanodine Receptor Type 2 in the Heart

A. Scholten, A. Heck, S. Jung, 2021, Proteomes.

Identification of MicroRNA‐mRNA Dysregulations in Paroxysmal Atrial Fibrillation

Min Zhang, X. Wehrens, D. Dobrev, 2015, International journal of cardiology.

A Coregulatory Network of NR2F1 and microRNA-140

David Y. Chiang, F. Pereira, David W. Cuthbertson, 2013, PloS one.

SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity

A. Scholten, X. Wehrens, Qiongling Wang, 2016, Circulation research.

Effects of CaMKII-Mediated Phosphorylation of Ryanodine Receptor Type 2 on Islet Calcium Handling, Insulin Secretion, and Glucose Tolerance

X. Wehrens, V. Yechoor, David Y. Chiang, 2013, PLoS ONE.

Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.

X. Wehrens, D. Dobrev, N. Voigt, 2013, Cardiovascular research.

CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome.

X. Wehrens, Jerald W Curran, P. Mohler, 2012, Heart rhythm.

Regulating the regulator: Insights into the cardiac protein phosphatase 1 interactome.

A. Heck, X. Wehrens, D. Dobrev, 2016, Journal of molecular and cellular cardiology.

Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients.

A. Scholten, X. Wehrens, D. Dobrev, 2015, Journal of the American College of Cardiology.

Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation.

Albert J R Heck, Na Li, Dobromir Dobrev, 2019, Circulation.

Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling

Xun Ai, X. Wehrens, Jiang Chang, 2015, Circulation research.

The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2

A. Karma, K. Moshal, C. Macrae, 2020, The Journal of Biological Chemistry.

LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor) Regulates Cardiac L-Type Calcium Channels by Modulating NEDD (Neural Precursor Cell Expressed Developmentally Downregulated Protein) 4-1 Ubiquitin Ligase

Tae Yun Kim, A. Karma, D. Terentyev, 2019, Circulation: Genomic and Precision Medicine.

Relation of Cardiac Dysfunction to Rhythm Abnormalities in Patients With Duchenne or Becker Muscular Dystrophies.

H. Allen, Jeffrey J. Kim, T. Lotze, 2016, American Journal of Cardiology.

Loss-of-Function SCN5A Mutations Associated With Sinus Node Dysfunction, Atrial Arrhythmias, and Poor Pacemaker Capture

X. Wehrens, Jeffrey J. Kim, David Y. Chiang, 2015, Circulation. Arrhythmia and electrophysiology.

Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.

X. Wehrens, D. Dobrev, N. Voigt, 2014, Cardiovascular research.

LITAF Regulates Cardiac L-type Calcium Channels by Modulating NEDD4-1 Ubiquitin Ligase.

Tae Yun Kim, A. Karma, D. Terentyev, 2019, Circulation. Genomic and precision medicine.