Mike Hoare

发表

Ultra scale-down tools for in-process formulation of biopharmaceuticals

H Baldascini, P Blas, Daniel G. Bracewell, 2005 .

Crystallisation for selective protein recovery from fermentation broth. In European Symposium on Biochemical Engineering Science 3. Copenhagen, September

Mike Hoare, A Dorward, C Jacobsen, 2000 .

The use of rapid on-line monitoring from within an expanded bed for the control of separations exhibiting fast breakthrough characterisitcs to maximise productivity

Nigel J. Titchener-Hooker, Mike Hoare, Nicholas Willoughby, 2000 .

A NEW APPROACH TO THE DESIGN AND CONTROL OF PROTEIN-PURIFICATION OPERATIONS

Mike Hoare, Paul G. Richardson, R. Ravenhall, 1988 .

Levereaging rapid data aquisition, scale-down devices & models to improve bioprocesses (Oral presentation)

Nigel J. Titchener-Hooker, Daniel G. Bracewell, Mike Hoare, 2002 .

THE INTEGRATED DESIGN OF RECOMBINANT PROTEIN-PRODUCTION VIA INCLUSION-BODIES

Mike Hoare, Nj Titchenerhooker, Peter Dunnill, 1989 .

RAPID FERMENTATION MONITORING WITH AN OPTICAL BIOSENSOR

Mike Hoare, A Gill, J Harrison, 1995 .

Novel scale-down techniques in bioprocess operations. Applications of miniaturization techniques in development and validation of processes for manufacture of advanced biopharmaceuticals

H Baldascini, Daniel G. Bracewell, Mike Hoare, 2003 .

Innovation in scale-down methodology: integrating ultra scale-down devices, modelling and visualisation

H Baldascini, Daniel G. Bracewell, Mike Hoare, 2003 .

Use of an ultra scale down device to predict degradation of biopharmaceuticals in recovery, purification and formulation operations.

H Baldascini, Daniel G. Bracewell, Mike Hoare, 2003 .

Optical biosensors to quantify product for fermentation monitoring

Mike Hoare, A Gill, Pa Lowe, 1996 .

THE SPECIFICATIONS OF STATIC SEALS FOR CONTAINED OPERATIONS : AN ENGINEERING APPRAISAL

Nigel J. Titchener-Hooker, Mike Hoare, S. P. Vranch, 1993 .

Viable cell recovery by capillary shear from mESC derived embryoid bodies.

Farlan S. Veraitch, Mike Hoare, Ioannis Papantoniou, 2008 .

Evaluation of options for harvest of a recombinant E. Coli fermentation producing a domain antibody using ultra scale‐down techniques and pilot‐scale verification

Mike Hoare, Alex Chatel, Gary Finka, 2016, Biotechnology progress.

The use of a surface active agent in the protection of a fusion protein during bioprocessing

Mike Hoare, Berend Tolner, K. Chester, 2018, Biotechnology and bioengineering.

DISRUPTION OF PROTEIN PRECIPITATES DURING SHEAR IN COUETTE-FLOW AND IN PUMPS

Mike Hoare, T. J. Narendranathan, Peter Dunnill, 1982 .

Bioengineering the Liver: Scale-Up and Cool Chain Delivery of the Liver Cell Biomass for Clinical Targeting in a Bioartificial Liver Support System

Cécile Legallais, Mike Hoare, Humphrey Hodgson, 2013, BioResearch open access.

Enhancing the selective extracellular location of a recombinant E. coli domain antibody by management of fermentation conditions

Mike Hoare, Gary Finka, Mark Uden, 2015, Applied Microbiology and Biotechnology.

Determination of bioactive protein product produced during fermentation using an optical biosensor.

Mike Hoare, I Holwill, A Gill, 1996 .

Studies of the effect of shear on globular proteins: Extension to high shear fields and to pumps

Mike Hoare, T. J. Narendranathan, Peter Dunnill, 1981 .

Rapid analysis of biosensor data using initial rate determination and its application to bioprocess monitoring

Mike Hoare, I Holwill, A Gill, 1996 .

An ultra scale‐down characterization of low shear stress primary recovery stages to enhance selectivity of fusion protein recovery from its molecular variants

Simyee Kong, Mike Hoare, Shaun McNulty, 2013, Biotechnology and bioengineering.

Large‐scale plasmid DNA processing: evidence that cell harvesting and storage methods affect yield of supercoiled plasmid DNA

Simyee Kong, Mike Hoare, Nicholas Willoughby, 2008, Biotechnology and applied biochemistry.

Selective flocculation of cellular contaminants from soluble proteins using polyethyleneimine: A study of several organisms and polymer molecular weights

Mike Hoare, David E. Salt, Peter Dunnill, 1995 .

THE EFFECT OF FLUID-JET MIXING ON PROTEIN PRECIPITATE GROWTH DURING LOW-FREQUENCY CONDITIONING

Nigel J. Titchener-Hooker, Mike Hoare, M. Hoare, 1992 .

The formation of protein precipitates and their centrifugal recovery

Mike Hoare, Peter Dunnill, D. J. Bell, 1983 .

Rapid monitoring of recombinant protein products: a comparison of current technologies.

Mike Hoare, David C James, D. James, 2002, Trends in biotechnology.

Effect of fouling on the capacity and breakthrough characteristics of a packed bed ion exchange chromatography column

Nigel J. Titchener-Hooker, Mike Hoare, M. Hoare, 2006, Bioprocess and biosystems engineering.

Use of focused acoustics for cell disruption to provide ultra scale‐down insights of microbial homogenization and its bioprocess impact—recovery of antibody fragments from rec E. coli

Mike Hoare, Alex Chatel, Alison Tang, 2012, Biotechnology and bioengineering.

Ultra scale‐down studies of the effect of shear on cell quality; Processing of a human cell line for cancer vaccine therapy

Mike Hoare, Ryan McCoy, M. Hoare, 2009, Biotechnology progress.

Development of a high resolution UV spectrophotometer for at-line monitoring of bioprocesses

Mike Hoare, Jonathan Hill, Trevor Smith, 2002 .

Optimization of fractional precipitation for protein purification

Mike Hoare, Peter Dunnill, Paul G. Richardson, 1989 .

Sub‐population analysis of human cancer vaccine cells—ultra scale‐down characterization of response to shear

Mike Hoare, Ryan McCoy, M. Hoare, 2010, Biotechnology and bioengineering.

Mimic of a large‐scale diafiltration process by using ultra scale‐down rotating disc filter

Alan Craig, Mike Hoare, Yuhong Zhou, 2009, Biotechnology progress.

Disruption of baker's yeast in a high-pressure homogenizer. New evidence on mechanism

Mike Hoare, Peter Dunnill, M. Hoare, 1990 .

An ultra scale‐down approach to study the interaction of fermentation, homogenization, and centrifugation for antibody fragment recovery from rec E. coli

Mike Hoare, Shaukat Ali, Qiang Li, 2013, Biotechnology and bioengineering.

Ultra scale‐down approach to correct dispersive and retentive effects in small‐scale columns when predicting larger scale elution profiles

Sunil Chhatre, Daniel G. Bracewell, H Baldascini, 2009, Biotechnology progress.

The release of single cells from embryoid bodies in a capillary flow device

Farlan S. Veraitch, Mike Hoare, Ioannis Papantoniou, 2011 .

Regenerative medicine bioprocessing: the need to learn from the experience of other fields.

Mike Hoare, Chris Mason, C. Mason, 2006, Regenerative medicine.

Monitoring and optimisation of fractional protein precipitation by flow-injection analysis

Mike Hoare, I Holwill, R. Ravenhall, 1996 .

Ultra Scale-Down Characterization of the Impact of Conditioning Methods for Harvested Cell Broths on Clarification by Continuous Centrifugation—Recovery of Domain Antibodies from rec E. coli

Mike Hoare, Alex Chatel, Peter Kumpalume, 2013, Biotechnology and bioengineering.

Protein precipitate recovery in industrial centrifuge

Mike Hoare, M. Boychyn, M. Bulmer, 1998 .